Search Results - "International journal for numerical methods in biomedical engineering"

An efficient algorithm for mapping imaging data to 3D unstructured grids in computational biomechanics by Einstein, Daniel R., Kuprat, Andrew P., Jiao, Xiangmin, Carson, James P., Einstein, David M., Jacob, Richard E., Corley, Richard A.

“…SUMMARY Geometries for organ scale and multiscale simulations of organ function are now routinely derived from imaging data. However, medical images may also…”
Get full text

A review of personalized blood glucose prediction strategies for T1DM patients by Oviedo, Silvia, Vehí, Josep, Calm, Remei, Armengol, Joaquim

“…This paper presents a methodological review of models for predicting blood glucose (BG) concentration, risks and BG events. The surveyed models are classified…”
Get full text

Integration of element specific persistent homology and machine learning for protein‐ligand binding affinity prediction by Cang, Zixuan, Wei, Guo‐Wei

“…Protein‐ligand binding is a fundamental biological process that is paramount to many other biological processes, such as signal transduction, metabolic…”
Get full text

Persistent spectral graph by Wang, Rui, Nguyen, Duc Duy, Wei, Guo‐Wei

“…Persistent homology is constrained to purely topological persistence, while multiscale graphs account only for geometric information. This work introduces…”
Get full text

Hybrid finite difference/finite element immersed boundary method by E. Griffith, Boyce, Luo, Xiaoyu

“…The immersed boundary method is an approach to fluid‐structure interaction that uses a Lagrangian description of the structural deformations, stresses, and…”
Get full text

Persistent homology analysis of protein structure, flexibility, and folding by Xia, Kelin, Wei, Guo-Wei

“…SUMMARYProteins are the most important biomolecules for living organisms. The understanding of protein structure, function, dynamics, and transport is one of…”
Get full text

A framework for designing patient‐specific bioprosthetic heart valves using immersogeometric fluid–structure interaction analysis by Xu, Fei, Morganti, Simone, Zakerzadeh, Rana, Kamensky, David, Auricchio, Ferdinando, Reali, Alessandro, Hughes, Thomas J. R., Sacks, Michael S., Hsu, Ming‐Chen

“…Numerous studies have suggested that medical image derived computational mechanics models could be developed to reduce mortality and morbidity due to…”
Get full text

Diagnosis of Alzheimer's disease with Sobolev gradient‐based optimization and 3D convolutional neural network by Goceri, Evgin

“…Alzheimer's disease is a neuropsychiatric, progressive, also an irreversible disease. There is not an effective cure for the disease. However, early diagnosis…”
Get full text

A benchmark study of numerical schemes for one-dimensional arterial blood flow modelling by Boileau, Etienne, Nithiarasu, Perumal, Blanco, Pablo J., Müller, Lucas O., Fossan, Fredrik Eikeland, Hellevik, Leif Rune, Donders, Wouter P., Huberts, Wouter, Willemet, Marie, Alastruey, Jordi

“…Summary Hæmodynamical simulations using one‐dimensional (1D) computational models exhibit many of the features of the systemic circulation under normal and…”
Get full text

A rule‐based method to model myocardial fiber orientation in cardiac biventricular geometries with outflow tracts by Doste, Ruben, Soto‐Iglesias, David, Bernardino, Gabriel, Alcaine, Alejandro, Sebastian, Rafael, Giffard‐Roisin, Sophie, Sermesant, Maxime, Berruezo, Antonio, Sanchez‐Quintana, Damian, Camara, Oscar

“…Rule‐based methods are often used for assigning fiber orientation to cardiac anatomical models. However, existing methods have been developed using data mostly…”
Get full text

A systematic comparison between 1-D and 3-D hemodynamics in compliant arterial models by Xiao, Nan, Alastruey, Jordi, Alberto Figueroa, C.

“…SUMMARYWe present a systematic comparison of computational hemodynamics in arteries between a one‐dimensional (1‐D) and a three‐dimensional (3‐D) formulation…”
Get full text

A mathematical model that integrates cardiac electrophysiology, mechanics, and fluid dynamics: Application to the human left heart by Bucelli, Michele, Zingaro, Alberto, Africa, Pasquale Claudio, Fumagalli, Ivan, Dede', Luca, Quarteroni, Alfio

“…We propose a mathematical and numerical model for the simulation of the heart function that couples cardiac electrophysiology, active and passive mechanics and…”
Get full text

Fully coupled fluid‐electro‐mechanical model of the human heart for supercomputers by Santiago, Alfonso, Aguado‐Sierra, Jazmín, Zavala‐Aké, Miguel, Doste‐Beltran, Ruben, Gómez, Samuel, Arís, Ruth, Cajas, Juan C., Casoni, Eva, Vázquez, Mariano

“…In this work, we present a fully coupled fluid‐electro‐mechanical model of a 50th percentile human heart. The model is implemented on Alya, the BSC…”
Get full text

A guide to uncertainty quantification and sensitivity analysis for cardiovascular applications by Eck, Vinzenz Gregor, Donders, Wouter Paulus, Sturdy, Jacob, Feinberg, Jonathan, Delhaas, Tammo, Hellevik, Leif Rune, Huberts, Wouter

“…Summary As we shift from population‐based medicine towards a more precise patient‐specific regime guided by predictions of verified and well‐established…”
Get full text

Automated generation of 0D and 1D reduced‐order models of patient‐specific blood flow by Pfaller, Martin R., Pham, Jonathan, Verma, Aekaansh, Pegolotti, Luca, Wilson, Nathan M., Parker, David W., Yang, Weiguang, Marsden, Alison L.

“…Three‐dimensional (3D) cardiovascular fluid dynamics simulations typically require hours to days of computing time on a high‐performance computing cluster…”
Get full text

Polygonal surface processing and mesh generation tools for the numerical simulation of the cardiac function by Fedele, Marco, Quarteroni, Alfio

“…In order to simulate the cardiac function for a patient‐specific geometry, the generation of the computational mesh is crucially important. In practice, the…”
Get full text

Non‐Newtonian blood rheology impacts left atrial stasis in patient‐specific simulations by Gonzalo, Alejandro, García‐Villalba, Manuel, Rossini, Lorenzo, Durán, Eduardo, Vigneault, Davis, Martínez‐Legazpi, Pablo, Flores, Oscar, Bermejo, Javier, McVeigh, Elliot, Kahn, Andrew M., del Alamo, Juan C.

“…The lack of mechanically effective contraction of the left atrium (LA) during atrial fibrillation (AF) disturbs blood flow, increasing the risk of thrombosis…”
Get full text

Impact of baseline coronary flow and its distribution on fractional flow reserve prediction by Müller, Lucas O., Fossan, Fredrik E., Bråten, Anders T., Jørgensen, Arve, Wiseth, Rune, Hellevik, Leif R.

“…Model‐based prediction of fractional flow reserve (FFR) in the context of stable coronary artery disease (CAD) diagnosis requires a number of modelling…”
Get full text

DG‐GL: Differential geometry‐based geometric learning of molecular datasets by Nguyen, Duc Duy, Wei, Guo‐Wei

“…Motivation: Despite its great success in various physical modeling, differential geometry (DG) has rarely been devised as a versatile tool for analyzing large,…”
Get full text

Stabilized second-order convex splitting schemes for Cahn-Hilliard models with application to diffuse-interface tumor-growth models by Wu, X., van Zwieten, G. J., van der Zee, K. G.

“…SUMMARYWe present unconditionally energy‐stable second‐order time‐accurate schemes for diffuse‐interface (phase‐field) models; in particular, we consider the…”
Get full text