Search Results - "Inoue, Takako"

Novel biomarkers for the management of chronic hepatitis B by Inoue, Takako, Tanaka, Yasuhito

“…Hepatitis B virus (HBV) cannot be eliminated completely from infected hepatocytes because of the presence of intrahepatic covalently closed circular DNA…”
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The Role of Hepatitis B Core-Related Antigen by Inoue, Takako, Tanaka, Yasuhito

“…Hepatitis B virus (HBV) cannot be completely eliminated from infected hepatocytes due to the existence of intrahepatic covalently closed circular DNA (cccDNA)…”
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Clinical efficacy of a novel, high-sensitivity HBcrAg assay in the management of chronic hepatitis B and HBV reactivation by Inoue, Takako, Kusumoto, Shigeru, Iio, Etsuko, Ogawa, Shintaro, Suzuki, Takanori, Yagi, Shintaro, Kaneko, Atsushi, Matsuura, Kentaro, Aoyagi, Katsumi, Tanaka, Yasuhito

“…A fully automated, novel high-sensitivity hepatitis B core-related antigen assay (iTACT-HBcrAg) has been developed. We demonstrate the clinical utility of…”
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Novel strategies for the early diagnosis of hepatitis B virus reactivation by Inoue, Takako, Matsui, Takeshi, Tanaka, Yasuhito

“…Hepatitis B virus (HBV) reactivation under systemic chemotherapy or immunosuppressive therapy is a serious complication among HBV‐resolved patients. Some…”
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Novel Biomarkers of Hepatitis B and Hepatocellular Carcinoma: Clinical Significance of HBcrAg and M2BPGi by Baudi, Ian, Inoue, Takako, Tanaka, Yasuhito

“…The hepatitis B virus (HBV) cannot be removed completely from infected hepatocytes, owing to the presence of intrahepatic covalently closed circular DNA…”
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Hepatitis B core-related antigen: A novel and promising surrogate biomarker to guide anti-hepatitis B virus therapy by Inoue, Takako, Watanabe, Takehisa, Tanaka, Yasuhito

“…The current requirement for biomarkers to detect hepatitis B virus (HBV) infection is polarized. One is a fully-automated and highly sensitive measurement…”
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Hepatitis B virus and its sexually transmitted infection - an update by Inoue, Takako, Tanaka, Yasuhito

“…About 5% of the world's population has chronic hepatitis B virus (HBV) infection, and nearly 25% of carriers develop chronic hepatitis, cirrhosis, and…”
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Cross-Protection of Hepatitis B Vaccination among Different Genotypes by Inoue, Takako, Tanaka, Yasuhito

“…Hepatitis B (HB) vaccination is the most effective method for preventing HB virus (HBV) infection. Universal HB vaccination containing recombinant HB surface…”
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Two Concepts of Hepatitis B Core-Related Antigen Assay: A Highly Sensitive and Rapid Assay or an Effective Tool for Widespread Screening by Inoue, Takako, Yagi, Shintaro, Tanaka, Yasuhito

“…Hepatitis B core-related antigen (HBcrAg) reflects the activity of intrahepatic covalently closed circular DNA. HBcrAg can be detected even in chronic…”
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Metastatic site as a predictor of nivolumab efficacy in patients with advanced non-small cell lung cancer: A retrospective multicenter trial by Tamiya, Motohiro, Tamiya, Akihiro, Inoue, Takako, Kimura, Madoka, Kunimasa, Kei, Nakahama, Kenji, Taniguchi, Yoshihiko, Shiroyama, Takayuki, Isa, Shun-Ichi, Nishino, Kazumi, Kumagai, Toru, Suzuki, Hidekazu, Hirashima, Tomonori, Atagi, Shinji, Imamura, Fumio

“…To conduct a retrospective multicenter trial to determine the significance of metastatic site as a predictor of nivolumab efficacy in patients with advanced…”
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Diagnostic Accuracy of Noninvasive Genotyping of EGFR in Lung Cancer Patients by Deep Sequencing of Plasma Cell-Free DNA by Uchida, Junji, Kato, Kikuya, Kukita, Yoji, Kumagai, Toru, Nishino, Kazumi, Daga, Haruko, Nagatomo, Izumi, Inoue, Takako, Kimura, Madoka, Oba, Shigeyuki, Ito, Yuri, Takeda, Koji, Imamura, Fumio

“…Genotyping of EGFR (epidermal growth factor receptor) mutations is indispensable for making therapeutic decisions regarding whether to use EGFR tyrosine kinase…”
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Clinical usefulness of a novel high-sensitivity hepatitis B core-related antigen assay to determine the initiation of treatment for HBV reactivation by Suzuki, Takanori, Inoue, Takako, Matsuura, Kentaro, Kusumoto, Shigeru, Hagiwara, Shinya, Ogawa, Shintaro, Yagi, Shintaro, Kaneko, Atsushi, Fujiwara, Kei, Watanabe, Takehisa, Aoyagi, Katsumi, Urata, Yukitomo, Tamori, Akihiro, Kataoka, Hiromi, Tanaka, Yasuhito

“…Backgrounds A fully automated, novel, high-sensitivity hepatitis B core-related antigen assay (iTACT-HBcrAg) has been developing. The purpose of this study is…”
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Monitoring of treatment responses and clonal evolution of tumor cells by circulating tumor DNA of heterogeneous mutant EGFR genes in lung cancer by Imamura, Fumio, Uchida, Junji, Kukita, Yoji, Kumagai, Toru, Nishino, Kazumi, Inoue, Takako, Kimura, Madoka, Oba, Shigeyuki, Kato, Kikuya

“…Highlights • EGFR ctDNA rapidly responded to an EGFR-TKI as a response predictor. • Transient ctDNA peaks of various EGFR mutants appeared during EGFR-TKI…”
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Hepatitis B Core-Related Antigen and New Therapies for Hepatitis B by Watanabe, Takehisa, Inoue, Takako, Tanaka, Yasuhito

“…The hepatitis B core-related antigen (HBcrAg) is an unprecedented novel HBV biomarker that plays an essential role in reflecting covalently closed circular DNA…”
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High levels of serum Mac-2-binding protein glycosylation isomer (M2BPGi) predict the development of hepatocellular carcinoma in hepatitis B patients treated with nucleot(s)ide analogues by Shinkai, Noboru, Nojima, Masanori, Iio, Etsuko, Matsunami, Kayoko, Toyoda, Hidenori, Murakami, Shuko, Inoue, Takako, Ogawa, Shintaro, Kumada, Takashi, Tanaka, Yasuhito

“…Background Nucleot(s)ide analogues (NA) can reduce the risk of hepatocellular carcinoma (HCC), but not completely prevent its development. Methods Two hundred…”
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Gut dysbiosis associated with clinical prognosis of patients with primary biliary cholangitis by Furukawa, Masanori, Moriya, Kei, Nakayama, Jiro, Inoue, Takako, Momoda, Rie, Kawaratani, Hideto, Namisaki, Tadashi, Sato, Shinya, Douhara, Akitoshi, Kaji, Kosuke, Kitade, Mitsuteru, Shimozato, Naotaka, Sawada, Yasuhiko, Saikawa, Soichiro, Takaya, Hiroaki, Kitagawa, Koh, Akahane, Takemi, Mitoro, Akira, Yamao, Junichi, Tanaka, Yasuhito, Yoshiji, Hitoshi

“…Aim Although some relationships between gut microbiota and liver diseases have been reported, it remains uncertain whether changes in gut microbiota owing to…”
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Dynamics of circulating tumor DNA represented by the activating and resistant mutations in epidermal growth factor receptor tyrosine kinase inhibitor treatment by Uchida, Junji, Imamura, Fumio, Kukita, Yoji, Oba, Shigeyuki, Kumagai, Toru, Nishino, Kazumi, Inoue, Takako, Kimura, Madoka, Kato, Kikuya

“…Circulating tumor DNA (ctDNA) is an emerging field of cancer research. For lung cancer, non‐invasive genotyping of EGFR is the foremost application. The…”
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Efficacy of anti-PD-1/PD-L1 antibodies after discontinuation due to adverse events in non-small cell lung cancer patients (HANSHIN 0316) by Tachihara, Motoko, Negoro, Shunichi, Inoue, Takako, Tamiya, Motohiro, Akazawa, Yuki, Uenami, Takeshi, Urata, Yoshiko, Hattori, Yoshihiro, Hata, Akito, Katakami, Nobuyuki, Yokota, Soichiro

“…Immune checkpoint inhibitors (ICIs) have emerged as promising therapeutic agents in non-small cell lung cancer (NSCLC). However, the duration for which ICIs…”
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Management of hepatitis B virus (HBV) reactivation in patients with resolved HBV infection based on a highly sensitive HB core‐related antigen assay by Hagiwara, Shinya, Kusumoto, Shigeru, Inoue, Takako, Ogawa, Shintaro, Narita, Tomoko, Ito, Asahi, Ri, Masaki, Komatsu, Hirokazu, Suzuki, Takanori, Matsuura, Kentaro, Yagi, Shintaro, Kaneko, Atsushi, Aoyagi, Katsumi, Iida, Shinsuke, Tanaka, Yasuhito

“…Aims To prevent hepatitis B virus (HBV) reactivation‐related hepatitis, we examined the clinical usefulness of a highly sensitive HB core‐related antigen…”
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Manual route modification using an oblique method following automatic virtual bronchoscopic navigation by Inoue, Takako, Kawamura, Takahisa, Kunimasa, Kei, Tamiya, Motohiro, Kuhara, Hanako, Nishino, Kazumi, Odani, Satomi, Imamura, Fumio, Kumagai, Toru, Miyake, Kotaro

“…Virtual automatic bronchoscopic navigation (VBN) systems to determine the route to peripheral pulmonary lesions (PPLs) in lung cancer can improve diagnostic…”
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