Search Results - "Inoue, Keizo"

Cathepsin G-induced malignant progression of MCF-7 cells involves suppression of PAF signaling through induced expression of PAFAH1B2 by Tanigawa, Kazunari, Kiriya, Mitsuo, Hayashi, Yasuhiro, Shinden, Yoshiaki, Kijima, Yuko, Natsugoe, Shoji, Sumimoto, Takahiro, Morimoto-Kamata, Riyo, Yui, Satoru, Hama, Kotaro, Yokoyama, Kazuaki, Nakamura, Yasuhiro, Suzuki, Koichi, Nojiri, Hisao, Inoue, Keizo, Karasawa, Ken

“…Breast cancer is primarily classified into ductal and lobular types, as well as into noninvasive and invasive cancer. Invasive cancer involves lymphatic and…”
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Acyl Chain Preference in Foam Cell Formation from Mouse Peritoneal Macrophages by Fujiwara, Yuko, Hama, Kotaro, Tsukahara, Makoto, Izumi-Tsuzuki, Ryosuke, Nagai, Toru, Ohe-Yamada, Mihoko, Inoue, Keizo, Yokoyama, Kazuaki

“…Macrophage foam cells play critical roles in the initiation and development of atherosclerosis by synthesizing and accumulating cholesteryl ester (CE) in lipid…”
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Autotaxin Has Lysophospholipase D Activity Leading to Tumor Cell Growth and Motility by Lysophosphatidic Acid Production by Umezu-Goto, Makiko, Kishi, Yasuhiro, Taira, Akitsu, Hama, Kotaro, Dohmae, Naoshi, Takio, Koji, Yamori, Takao, Mills, Gordon B., Inoue, Keizo, Aoki, Junken, Arai, Hiroyuki

“…Autotaxin (ATX) is a tumor cell motility-stimulating factor, originally isolated from melanoma cell supernatants. ATX had been proposed to mediate its effects…”
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Molecular Cloning and Characterization of a Novel Human G-protein-coupled Receptor, EDG7, for Lysophosphatidic Acid by Bandoh, Koji, Aoki, Junken, Hosono, Hiroyuki, Kobayashi, Susumu, Kobayashi, Tetsuyuki, Murakami-Murofushi, Kimiko, Tsujimoto, Masafumi, Arai, Hiroyuki, Inoue, Keizo

“…Lysophosphatidic acid (LPA), together with sphingosine 1-phosphate, is a bioactive lipid mediator that acts on G-protein-coupled receptors to evoke multiple…”
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Plasma platelet activating factor-acetylhydrolase (PAF-AH) by Karasawa, Ken, Harada, Ayako, Satoh, Noriko, Inoue, Keizo, Setaka, Morio

“…The platelet-activating factor-acetylhydrolase (PAF-AH) is an enzyme which catalyzes the hydrolysis of acetyl ester at the sn-2 position of PAF. The family of…”
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Lysenin, a Novel Sphingomyelin-specific Binding Protein by Yamaji, A, Sekizawa, Y, Emoto, K, Sakuraba, H, Inoue, K, Kobayashi, H, Umeda, M

“…Lysenin, a novel 41-kDa protein purified from coelomic fluid of the earthworm Eisenia foetida , induced erythrocyte lysis. Preincubation of lysenin with…”
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Platelet-Activating Factor Acetylhydrolase (PAF-AH) by Arai, Hiroyuki, Koizumi, Hiroyuki, Aoki, Junken, Inoue, Keizo

“…Platelet-activating factor (PAF) is one of the most potent lipid messengers involved in a variety of physiological events. The acetyl group at the sn-2…”
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Expression Cloning of a Novel Scavenger Receptor from Human Endothelial Cells by Adachi, Hideki, Tsujimoto, Masafumi, Arai, Hiroyuki, Inoue, Keizo

“…Scavenger receptors mediate the endocytosis of chemically modified lipoproteins, such as acetylated low density lipoprotein (Ac-LDL) and oxidized LDL (Ox-LDL),…”
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Identification of a PDZ-Domain-Containing Protein That Interacts with the Scavenger Receptor Class B Type I by Ikemoto, Mamoru, Arai, Hiroyuki, Feng, Dongdong, Tanaka, Kazumi, Aoki, Junken, Dohmae, Naoshi, Takio, Koji, Adachi, Hideki, Tsujimoto, Masafumi, Inoue, Keizo

“…The scavenger receptor class B type I (SR-BI) mediates the selective uptake of cholesteryl esters from high-density lipoprotein (HDL) and cholesterol secretion…”
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Targeted Disruption of Intracellular Type I Platelet Activating Factor-acetylhydrolase Catalytic Subunits Causes Severe Impairment in Spermatogenesis by Koizumi, Hiroyuki, Yamaguchi, Noritaka, Hattori, Mitsuharu, Ishikawa, Tomo-O, Aoki, Junken, Taketo, Makoto M, Inoue, Keizo, Arai, Hiroyuki

“…Intracellular type I platelet activating factor-acetylhydrolase is a phospholipase that consists of a dimer of two homologous catalytic subunits α1 and α2 as…”
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SREC-II, a New Member of the Scavenger Receptor Type F Family, Trans-interacts with SREC-I through Its Extracellular Domain by Ishii, Junko, Adachi, Hideki, Aoki, Junken, Koizumi, Hiroyuki, Tomita, Susumu, Suzuki, Toshiharu, Tsujimoto, Masafumi, Inoue, Keizo, Arai, Hiroyuki

“…The scavenger receptor expressed by endothelial cells (SREC) with an extremely large cytoplasmic domain, was originally identified in a human endothelial cell…”
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Cell Adhesion to Phosphatidylserine Mediated by a Product of Growth Arrest-specific Gene 6 by Nakano, Toru, Ishimoto, Yoshikazu, Kishino, Junji, Umeda, Masato, Inoue, Keizo, Nagata, Kyoko, Ohashi, Kazumasa, Mizuno, Kensaku, Arita, Hitoshi

“…Gas6, a product of a growth arrest-specific gene 6, potentiates proliferation of vascular smooth muscle cells and prevents cell death of vascular smooth muscle…”
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Exposure of Phosphatidylethanolamine on the Surface of Apoptotic Cells by Emoto, Kazuo, Toyama-Sorimachi, Noriko, Karasuyama, Hajime, Inoue, Keizo, Umeda, Masato

“…In the early stages of apoptosis, phosphatidylserine (PS) is translocated from the inner side of the plasma membrane to the outer layer, which allows…”
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Redistribution of Phosphatidylethanolamine at the Cleavage Furrow of Dividing Cells during Cytokinesis by Emoto, Kazuo, Kobayashi, Toshihide, Yamaji, Akiko, Aizawa, Hiroyuki, Yahara, Ichiro, Inoue, Keizo, Umeda, Masato

“…Ro09-0198 is a tetracyclic polypeptide of 19 amino acids that recognizes strictly the structure of phosphatidylethanolamine (PE) and forms a tight equimolar…”
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Supernatant Protein Factor, Which Stimulates the Conversion of Squalene to Lanosterol, is a Cytosolic Squalene Transfer Protein and Enhances Cholesterol Biosynthesis by Shibata, Norihito, Arita, Makoto, Misaki, Yuko, Dohmae, Naoshi, Takio, Koji, Ono, Teruo, Inoue, Keizo, Arai, Hiroyuki

“…Squalene epoxidase, a membrane-associated enzyme that converts squalene to squalene 2,3-oxide, plays an important role in the maintenance of cholesterol…”
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Expression of phosphatidylserine-specific phospholipase A(1) mRNA in human THP-1-derived macrophages by Hosono, Hiroyuki, Homma, Masato, Ogasawara, Yoko, Makide, Kumiko, Aoki, Junken, Niwata, Hideaki, Watanabe, Machiko, Inoue, Keizo, Ohkohchi, Nobuhiro, Kohda, Yukinao

“…The expression of phosphatidylserine-specific phospholipase A(1) (PS-PLA(1)) is most upregulated in the genes of peripheral blood cells from chronic rejection…”
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alpha-Tocopherol transfer protein stimulates the secretion of alpha-tocopherol from a cultured liver cell line through a brefeldin A-insensitive pathway by Arita, M, Nomura, K, Arai, H, Inoue, K

“…Vitamin E (alpha-tocopherol) is a fat-soluble antioxidant that is transported by plasma lipoproteins in the body. alpha-Tocopherol taken up by the liver with…”
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Protection against Oxidative Stress-induced Cell Death by Intracellular Platelet-activating Factor-Acetylhydrolase II by Matsuzawa, Atsushi, Hattori, Kenji, Aoki, Junken, Arai, Hiroyuki, Inoue, Keizo

“…Platelet-activating factor-acetylhydrolase (PAF-AH), which removes the acetyl group at the sn-2 position of PAF, is distributed widely in tissues and plasma…”
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SRB1, a Class B Scavenger Receptor, Recognizes both Negatively Charged Liposomes and Apoptotic Cells by Fukasawa, Masayoshi, Adachi, Hideki, Hirota, Kotaro, Tsujimoto, Masafumi, Arai, Hiroyuki, Inoue, Keizo

“…Scavenger receptors mediate the recognition of a wide range of negatively charged macromolecules such as acetylated low-density lipoproteins (AcLDL). We…”
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Structure of a microbial homologue of mammalian platelet-activating factor acetylhydrolases: Streptomyces exfoliatus lipase at 1.9 å resolution by Wei, Yunyi, Swenson, Lora, Castro, Clementina, Derewenda, Urszula, Minor, Wladek, Arai, Hiroyuki, Aoki, Junken, Inoue, Keizo, Servin-Gonzalez, Luis, Derewenda, Zygmunt S

“…Background: Neutral lipases are ubiquitous and diverse enzymes. The molecular architecture of the structurally characterized lipases is similar, often despite…”
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