Search Results - "Inoue, Kazuko"

Bioactivation of diclofenac in human hepatocytes and the proposed human hepatic proteins modified by reactive metabolites by Inoue, Kazuko, Mizuo, Hitoshi, Ishida, Tomomi, Komori, Takafumi, Kusano, Kazutomi

“…To reveal putative bioactivation pathways of diclofenac, in vitro human liver materials such as microsomal fractions and hepatocytes were used to confirm…”
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Oxidative metabolic pathway of lenvatinib mediated by aldehyde oxidase by Inoue, Kazuko, Mizuo, Hitoshi, Kawaguchi, Shinki, Fukuda, Katsuyuki, Kusano, Kazutomi, Yoshimura, Tsutomu

“…Lenvatinib is a multityrosine kinase inhibitor that inhibits vascular endothelial growth factor receptors, and is being developed as an anticancer drug. P450s…”
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Unique metabolic pathway of [(14)C]lenvatinib after oral administration to male cynomolgus monkey by Inoue, Kazuko, Asai, Naoki, Mizuo, Hitoshi, Fukuda, Katsuyuki, Kusano, Kazutomi, Yoshimura, Tsutomu

“…Lenvatinib, a potent inhibitor of multiple tyrosine kinases, including vascular endothelial growth factor receptors 2 and 3, generated unique metabolites after…”
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Integrated cultural practices for whitefly management in organic tomato by Togni, Pedro Henrique Brum, Marouelli, Waldir Aparecido, Inoue‐Nagata, Alice Kazuko, Pires, Carmen Silvia Soares, Sujii, Edison Ryoiti

“…The whitefly Bemisia tabaci (Hemiptera: Aleyrodidae) is a serious pest among the diverse insect fauna of the tomato crop, especially when cultivated in organic…”
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Expression of P-glycoprotein in human placenta: relation to genetic polymorphism of the multidrug resistance (MDR)-1 gene by Tanabe, M, Ieiri, I, Nagata, N, Inoue, K, Ito, S, Kanamori, Y, Takahashi, M, Kurata, Y, Kigawa, J, Higuchi, S, Terakawa, N, Otsubo, K

“…To evaluate whether mutations in the human multidrug resistance (MDR)-1 gene correlate with placental P-glycoprotein (PGP) expression, we sequenced the MDR-1…”
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Thickness and density of adsorbed additive layer on metal surface in lubricant by neutron reflectometry by Hirayama, Tomoko, Torii, Takashi, Konishi, Yohei, Maeda, Masayuki, Matsuoka, Takashi, Inoue, Kazuko, Hino, Masahiro, Yamazaki, Dai, Takeda, Masayasu

“…The thickness and density of the adsorbed additive layer on a metal surface in lubricant were directly measured by neutron reflectometry. First, two kinds of…”
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Restricting weight gain during pregnancy in Japan: A controversial factor in reducing perinatal complications by Tsukamoto, Hiroko, Fukuoka, Hideoki, Inoue, Kazuko, Koyasu, Mieko, Nagai, Yasushi, Takimoto, Hidemi

“…Abstract Objective To evaluate the effectiveness of restricting weight gain during pregnancy to reduce perinatal complications. Study design The study was…”
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Risk factors for term small for gestational age infants in women with low prepregnancy body mass index by Watanabe, Hiroko, Inoue, Kazuko, Doi, Masako, Matsumoto, Momoyo, Ogasawara, Kayoko, Fukuoka, Hideoki, Nagai, Yasushi

“…Aim:  The purpose of our study was to investigate the association between low maternal prepregnancy body mass index (BMI) less than 18.5 kg/m2 and the…”
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Aromatic Substitution Reaction of 2-Chloropyridines Catalyzed by Microsomal Glutathione S-Transferase 1 by INOUE, Kazuko, OHE, Tomoyuki, MORI, Kenichi, SAGARA, Takeshi, ISHII, Yasuyuki, CHIBA, Masato

“…We investigated the substitution reaction of a series of 2-chloropyridine derivatives catalyzed by rat liver microsomal glutathione S -transferase 1. Various…”
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A Trapping Method for Semi-quantitative Assessment of Reactive Metabolite Formation Using [35S]Cysteine and [14C]Cyanide by Inoue, Kazuko, Shibata, Yoshihiro, Takahashi, Hiroyuki, Ohe, Tomoyuki, Chiba, Masato, Ishii, Yasuyuki

“…A trapping approach for semi-quantitative assessment of bioactivation potential has been established for new chemical entities by using [35S]cysteine and…”
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Magnetic-Field-Induced Martensitic Transformation of Off-Stoichiometric Single-Crystal Ni2MnGa by INOUE, Kazuko, YAMAGUCHI, Yasuo, ISHII, Yoshinobu, YAMAUCHI, Hiroki, SHISHIDO, Toetsu

“…The effect of a magnetic field on the martensitic transformation of an off-stoichiometric Heusler type Ni2.16Mn0.78Ga1.06 single crystal has been revealed by…”
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Effect of magnetic field on martensite transformation in a polycrystalline Ni2MnGa by SOONJONG JEONG, INOUE, Kazuko, INOUE, Shozo, KOTERAZAWA, Keiji, TAYA, Minoru, INOUE, Kanryu

“…Shape change (strain) was observed for a polycrystalline thermoelastic ferromagnetic shape memory alloy Ni-9.5at.% Mn-27at.% Ga upon cooling and healing with…”
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Characterization and Experimental Host Range of a Brazilian Tomato Isolate of Tomato severe rugose virus by Barbosa, Júlio César, Barreto, Sarah da Silva, Inoue-Nagata, Alice Kazuko, Rezende, Jorge Alberto Marques

“…We report the complete molecular characterization of the DNA‐A and DNA‐B of a Brazilian tomato isolate of Tomato severe rugose virus (ToSRV) and the…”
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Cucurbit aphid-borne yellows virus from melon plants in Brazil is an interspecific recombinant by Costa, Thiago Marques, Blawid, Rosana, Aranda, Miguel A., Freitas, Débora Maria Sansini, Andrade, Genira Pereira, Inoue-Nagata, Alice Kazuko, Nagata, Tatsuya

“…Melon plants with severe yellowing symptoms from in Brazil were analyzed by high-throughput sequencing. Sequences homologous to the genome of the polerovirus…”
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Effect of ATP on preadipocyte migration and adipocyte differentiation by activating P2Y receptors in 3T3-L1 cells by Omatsu-Kanbe, Mariko, Inoue, Kazuko, Fujii, Yusuke, Yamamoto, Takefumi, Isono, Takahiro, Fujita, Norihisa, Matsuura, Hiroshi

“…The effect of extracellular ATP on adipogenesis was investigated using the mouse 3T3-L1 cell line. Incubation of cells with ATP (1-100 microM) for 5 min…”
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Neutron Diffraction Study of Martensitic Transformation of Off-Stoichiometric Single-Crystal Ni2MnGa by INOUE, Kazuko, YAMAGUCHI, Yasuo, HIRAKA, Haruhiro, SHISHIDO, Toetsu, MAEDA, Hidefumi, TSUNODA, Yorihiko

“…Neutron diffraction was applied to investigate the martensitic transformation of an off-stoichiometric Heusler-type Ni2.16Mn0.78Ga1.06 single crystal…”
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A Temporal Diversity Analysis of Brazilian Begomoviruses in Tomato Reveals a Decrease in Species Richness between 2003 and 2016 by Souza, Tadeu Araujo, Silva, João Marcos Fagundes, Nagata, Tatsuya, Martins, Thaís Pereira, Nakasu, Erich Yukio Tempel, Inoue-Nagata, Alice Kazuko

“…Understanding the molecular evolution and diversity changes of begomoviruses is crucial for predicting future outbreaks of the begomovirus disease in tomato…”
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Tomato fruit blotch virus cytopathology strengthens evolutionary links between plant blunerviruses and insect negeviruses by Kitajima, Elliot Watanabe, Nakasu, Erich Yukio Tempel, Inoue-Nagata, Alice Kazuko, Salaroli, Renato Barbosa, Ramos-González, Pedro Luis

“…ABSTRACT Tomato fruit blotch virus (ToFBV) is a blunervirus that causes blotches on mature tomato (Solanum lycopersicon L.) fruits in Italy and Australia in…”
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Evidence of Spread of Bemisia tabaci (Hemiptera: Aleyrodidae) Mediated by Internal Transportation of Ornamental Plants in Brazil by da Silva Rodrigues, Cristiano, Nakasu, Erich Yukio Tempel, Ortiz, Gustavo Vilela, Pereira, José Luiz, Lucena-Leandro, Vivian dos Santos, Rêgo-Machado, Camila de Moraes, Souza, Tadeu Araújo de, Martins, Thais Pereira, Nagata, Alice Kazuko Inoue

“…Two Bemisia tabaci (Gennadius) species, Middle East-Asia Minor 1 (MEAM1) and Mediterranean (MED), are major pests that are dispersed throughout the world…”
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Characterization of bean necrotic mosaic virus: a member of a novel evolutionary lineage within the Genus Tospovirus by de Oliveira, Athos Silva, Melo, Fernando Lucas, Inoue-Nagata, Alice Kazuko, Nagata, Tatsuya, Kitajima, Elliot Watanabe, Resende, Renato Oliveira

“…Tospoviruses (Genus Tospovirus, Family Bunyaviridae) are phytopathogens responsible for significant worldwide crop losses. They have a tripartite negative and…”
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