Search Results - "Inns, Stephen"
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Constipation screening in people taking clozapine: A diagnostic accuracy study
Published in Schizophrenia research (01-06-2020)“…Clozapine is the favoured antipsychotic for treatment-refractory schizophrenia but its safe use requires careful adverse-effect management. Clozapine-induced…”
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Effects of Clozapine on the Gut: Cross-Sectional Study of Delayed Gastric Emptying and Small and Large Intestinal Dysmotility
Published in CNS drugs (01-01-2019)“…Background Gastrointestinal hypomotility in people taking clozapine is common, poorly understood and potentially dangerous. It causes distress and sometimes…”
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Comparative Analysis of Body Image Dissatisfaction, Depression, and Health-Related Quality of Life in Adults with Type 1 Diabetes: A Case-Control Study
Published in Nutrients (01-09-2023)“…(1) Objective: This case-control study investigated body image dissatisfaction, depression, and health-related quality of life (HRQoL) in adults with type 1…”
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Controlled infection with cryopreserved human hookworm induces CTLA-4 expression on Tregs and upregulates tryptophan metabolism
Published in Gut microbes (31-12-2024)“…Infecting humans with controlled doses of helminths, such as human hookworm (termed hookworm therapy), is proposed to prevent or treat various intestinal and…”
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New Zealand Society of Gastroenterology guidelines for the management of refractory ulcerative colitis
Published in New Zealand medical journal (16-10-2015)“…Summarises the literature regarding the management of patients with ulcerative colitis who are dependent on corticosteroid for control of symptoms, or…”
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Quality of Life Factors in Adults with Eosinophilic Oesophagitis in New Zealand
Published in Nutrients (10-10-2024)“…Eosinophilic oesophagitis (EoE) is an immune-mediated oesophageal disorder causing dysphagia. Patients with EoE experience reduced QoL due to symptoms;…”
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8 Year Observational Study of Esophageal Dilatation for Benign Oesophageal Stricture
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Eosinophilic oesophagitis : an emerging important cause for undiagnosed dysphagia
Published in New Zealand medical journal (10-03-2006)“…Presents a retrospective case series in which eight patients with eosinophilic oesophagitis are described. Discusses the mode of presentation, history,…”
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Helminths' therapeutic potential to treat intestinal barrier dysfunction
Published in Allergy (Copenhagen) (01-11-2023)“…The intestinal barrier is a dynamic multi-layered structure which can adapt to environmental changes within the intestinal lumen. It has the complex task of…”
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Ethnicity data audit in a secondary care gastroenterology service
Published in New Zealand medical journal (11-11-2022)“…Audits the quality of ethnicity data stored under National Health Index (NHI) in the Hutt Hospital database against a fresh collection of self-identified…”
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A Noninferiority Randomized Clinical Trial of the Use of the Smartphone-Based Health Applications IBDsmart and IBDoc in the Care of Inflammatory Bowel Disease Patients
Published in Inflammatory bowel diseases (18-06-2020)“…Abstract Background Providing timely follow-up care for patients with inflammatory bowel disease in remission is important but often difficult because of…”
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Helminth infection induces a distinct subset of CD101 hi lung tissue-infiltrating eosinophils that are differentially regulated by type 2 cytokines
Published in Immunology and cell biology (01-09-2024)“…Eosinophils play divergent roles in health and disease, contributing to both immunoregulatory and proinflammatory responses. Helminth infection is strongly…”
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Ozanimod Induction and Maintenance Treatment for Ulcerative Colitis
Published in The New England journal of medicine (05-05-2016)“…In a placebo-controlled phase 2 trial involving patients with ulcerative colitis, ozanimod, an oral agonist of sphingosine-1-phosphate receptor subtypes 1 and…”
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The immunoregulatory potential of eosinophil subsets
Published in Immunology and cell biology (01-10-2024)“…Eosinophils have traditionally been viewed as pathological effector cells primarily involved in antiparasitic and allergic immune reactions; however, it is…”
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VITALITY: impact of adalimumab on health and disability outcomes in patients with Crohn's disease, rheumatoid arthritis, or psoriasis treated in clinical practice in New Zealand
Published in Current medical research and opinion (03-10-2019)“…Objective: VITALITY, a 6-month, multicenter, prospective, observational study, assessed the effects of originator adalimumab (HUMIRA) on health and disability…”
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Helminth infection induces a distinct subset of CD101hi lung tissue–infiltrating eosinophils that are differentially regulated by type 2 cytokines
Published in Immunology and cell biology (01-09-2024)“…Eosinophils play divergent roles in health and disease, contributing to both immunoregulatory and proinflammatory responses. Helminth infection is strongly…”
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A Small Intestinal Helminth Infection Alters Colonic Mucus and Shapes the Colonic Mucus Microbiome
Published in International journal of molecular sciences (08-11-2024)“…Infecting humans with controlled doses of small intestinal helminths, such as human hookworm, is proposed as a therapy for the colonic inflammatory disease…”
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Controlled Hookworm Infection for Medication-free Maintenance in Patients with Ulcerative Colitis: A Pilot, Double-blind, Randomized Control Trial
Published in Inflammatory bowel diseases (02-05-2024)“…Human hookworm has been proposed as a treatment for ulcerative colitis (UC). This pilot study assessed the feasibility of a full-scale randomized control trial…”
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