Search Results - "Inns, R H"

Efficacy of dimercapto chelating agents for the treatment of poisoning by percutaneously applied dichloro(2-chlorovinyl)arsine in rabbits by Inns, R H, Rice, P

“…The efficacy of three chelating agents, BAL, DMPS and DMSA has been evaluated in rabbits as treatments for systemic dichloro(2-chlorovinyl)arsine [lewisite]…”
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A histochemical study of changes observed in the mouse diaphragm after organophosphate poisoning by Bright, J E, Inns, R H, Tuckwell, N J, Griffiths, G D, Marrs, T C

“…A sublethal dose of sarin (GB, isopropyl methylphosphonofluoridate) was administered to mice. The animals were killed up to 28 d after dosing and frozen…”
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Comparative acute systemic toxicity of sodium arsenite and dichloro(2-chlorovinyl)arsine in rabbits by Inns, R H, Bright, J E, Marrs, T C

“…The acute intravenous toxicity of sodium arsenite and dichloro(2-chlorovinyl)arsine (lewisite) has been compared in rabbits to provide a quantitative and…”
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Evaluation of the efficacy of dimercapto chelating agents for the treatment of systemic organic arsenic poisoning in rabbits by Inns, R H, Rice, P, Bright, J E, Marrs, T C

“…1 The standard drug for the treatment of arsenic poisoning is BAL (dimercaprol). BAL possesses marked side-effects and a low safety ratio, drawbacks which new…”
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The formation of methaemoglobin by 4-aminopropiophenone (PAPP) and 4-(N-hydroxy) aminopropiophenone by Marrs, T C, Inns, R H, Bright, J E, Wood, S G

“…Oral dosing of rats with the cyanide antidote 4-aminopropiophenone (PAPP), brought about peak methaemoglobin levels at 15-40 min, but peak levels were attained…”
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Histochemical demonstration of calcium accumulation in muscle fibres after experimental organophosphate poisoning by Inns, R H, Tuckwell, N J, Bright, J E, Marrs, T C

“…The LD50 of subcutaneously-injected sarin (GB: isopropyl methylphosphonofluoridate) in mice was 172 micrograms kg-1. Mice were treated with sarin at doses…”
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The effect of storage upon cyanide in blood samples by Bright, J E, Inns, R H, Tuckwell, N J, Marrs, T C

“…CDPA blood of human origin was 'spiked' with a solution of potassium cyanide at four different concentrations. When such blood was left in contact with the…”
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The application of cell culture technology in the assessment of ultrawide band electromagnetic field hazards by Lindsay, C.D, Inns, R.H, Holden, S.J

“…As part of a programme addressing the potential health hazard of pulsed radiofrequency radiation (RFR), isolated cells in culture were exposed to pulsed,…”
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The efficacy of bispyridinium derivatives in the treatment of organophosphonate poisoning in the guinea-pig by Inns, R H, Leadbeater, L

“…The efficacy of a number of bispyridinium compounds, including both oxime and non-oxime derivatives, has been determined against poisoning by sarin, soman,…”
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Methaemoglobin production and reduction by methylene blue and the interaction of methylene blue with sodium nitrite in vivo by Marrs, T C, Bright, J E, Inns, R H

“…Methylene blue, at high concentrations, interferes with the estimation of methaemoglobin using the IL 282 CO-oximeter: the dye does not interfere with the…”
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Treatment of poisoning by soman by Leadbeater, L, Inns, R H, Rylands, J M

“…The efficacies of a number of drug treatment combinations in protecting guinea pigs against the lethal and incapacitating effects of soman (and sarin) have…”
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Differences between some biological properties of enantiomers of alkyl S-alkyl methylphosphonothioates by Hall, C R, Inch, T D, Inns, R H, Muir, A W, Sellers, D J, Smith, A P

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Studies of the pharmacokinetics and metabolism of 4-amino-propiophenone (PAPP) in rats, dogs and cynomolgus monkeys by Wood, S G, Fitzpatrick, K, Bright, J E, Inns, R H, Marrs, T C

“…The pharmacokinetics and metabolism of 4-aminopropiophenone (PAPP), a cyanide antidote, have been studied in rats, dogs and cynomolgus monkeys using 14C-PAPP…”
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delayed neuropathic effects of nerve agents and some other organophosphorus compounds by Gordon, J.J, Inns, R.H, Johnson, M.K, Leadbeater, L, Maidment, M.P, Upshall, D.G, Cooper, G.H, Rickard, R.L

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