Search Results - "Innis, Bruce L"

A Newcastle disease virus expressing a stabilized spike protein of SARS-CoV-2 induces protective immune responses by Sun, Weina, Liu, Yonghong, Amanat, Fatima, González-Domínguez, Irene, McCroskery, Stephen, Slamanig, Stefan, Coughlan, Lynda, Rosado, Victoria, Lemus, Nicholas, Jangra, Sonia, Rathnasinghe, Raveen, Schotsaert, Michael, Martinez, Jose L., Sano, Kaori, Mena, Ignacio, Innis, Bruce L., Wirachwong, Ponthip, Thai, Duong Huu, Oliveira, Ricardo Das Neves, Scharf, Rami, Hjorth, Richard, Raghunandan, Rama, Krammer, Florian, García-Sastre, Adolfo, Palese, Peter

“…Rapid development of COVID-19 vaccines has helped mitigating SARS-CoV-2 spread, but more equitable allocation of vaccines is necessary to limit the global…”
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Vital sign predictors of severe influenza among children in an emergent care setting by Rao, Suchitra, Moss, Angela, Lamb, Molly, Innis, Bruce L, Asturias, Edwin J

“…Background Decisions regarding the evaluation of children with influenza infection rely on the likelihood of severe disease. The role of early vital signs as…”
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A Randomized Trial of Candidate Inactivated Quadrivalent Influenza Vaccine versus Trivalent Influenza Vaccines in Children Aged 3—17 Years by Domachowske, Joseph B., Pankow-Culot, Heidemarie, Bautista, Milagros, Feng, Yang, Claeys, Carine, Peeters, Mathieu, Innis, Bruce L., Jain, Varsha

“…Background. Two antigenically distinct influenza B lineages have cocirculated since 2001, yet trivalent influenza vaccines (TIVs) contain 1 influenza B…”
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Immunogenicity, reactogenicity, and safety of inactivated quadrivalent influenza vaccine candidate versus inactivated trivalent influenza vaccine in healthy adults aged ≥18 years: A phase III, randomized trial by Tinoco, Juan Carlos, Pavia-Ruz, Noris, Cruz-Valdez, Aurelio, Aranza Doniz, Carlos, Chandrasekaran, Vijayalakshmi, Dewé, Walthère, Liu, Aixue, Innis, Bruce L, Jain, Varsha K

“…Highlights • Immunogenicity of QIV was non-inferior versus TIV for shared strains in adults. • Immunogenicity of QIV was superior to TIV for the…”
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Protection against varicella with two doses of combined measles-mumps-rubella-varicella vaccine versus one dose of monovalent varicella vaccine: a multicentre, observer-blind, randomised, controlled trial by Prymula, Roman, Prof, Bergsaker, Marianne Riise, MD, Esposito, Susanna, MD, Gothefors, Leif, Prof, Man, Sorin, MD, Snegova, Nadezhda, MD, Štefkovičova, Mária, MD, Usonis, Vytautas, Prof, Wysocki, Jacek, Prof, Douha, Martine, MSc, Vassilev, Ventzislav, PhD, Nicholson, Ouzama, Dr, Innis, Bruce L, MD, Willems, Paul, MD

“…Summary Background Rates of varicella have decreased substantially in countries implementing routine varicella vaccination. Immunisation is possible with…”
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A Newcastle Disease Virus (NDV) Expressing a Membrane-Anchored Spike as a Cost-Effective Inactivated SARS-CoV-2 Vaccine by Sun, Weina, McCroskery, Stephen, Liu, Wen-Chun, Leist, Sarah R, Liu, Yonghong, Albrecht, Randy A, Slamanig, Stefan, Oliva, Justine, Amanat, Fatima, Schäfer, Alexandra, Dinnon, 3rd, Kenneth H, Innis, Bruce L, García-Sastre, Adolfo, Krammer, Florian, Baric, Ralph S, Palese, Peter

“…A successful severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine must not only be safe and protective, but must also meet the demand on a…”
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Safety and Efficacy of a Recombinant Hepatitis E Vaccine by Shrestha, Sanjaya Kumar, Shrestha, Mrigendra Prasad, Scott, Robert McNair, Joshi, Durga Man, Mammen, Mammen P, Thapa, Gyan Bahadur, Thapa, Narbada, Myint, Khin Saw Aye, Fourneau, Marc, Kuschner, Robert A, David, Marie Pierre, Seriwatana, Jitvimol, Vaughn, David W, Safary, Assad, Endy, Timothy P, Innis, Bruce L

“…Seroprevalence studies suggest that one third of the world's population has been infected with hepatitis E virus (HEV). Infection, especially during pregnancy,…”
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A phase II, randomized, safety and immunogenicity study of a re-derived, live-attenuated dengue virus vaccine in healthy adults by Thomas, Stephen J, Eckels, Kenneth H, Carletti, Isabelle, De La Barrera, Rafael, Dessy, Francis, Fernandez, Stefan, Putnak, Robert, Toussaint, Jean-Francois, Sun, Wellington, Bauer, Kristen, Gibbons, Robert V, Innis, Bruce L

“…Two formulations of a new live tetravalent dengue virus (DENV) vaccine produced using re-derived master seeds from a precursor vaccine and that same precursor…”
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Immunogenicity, reactogenicity and safety of an inactivated quadrivalent influenza vaccine candidate versus inactivated trivalent influenza vaccine: a phase III, randomized trial in adults aged ≥18 years by Kieninger, Dorothee, Sheldon, Eric, Lin, Wen-Yuan, Yu, Chong-Jen, Bayas, Jose M, Gabor, Julian J, Esen, Meral, Fernandez Roure, Jose Luis, Narejos Perez, Silvia, Alvarez Sanchez, Carmen, Feng, Yang, Claeys, Carine, Peeters, Mathieu, Innis, Bruce L, Jain, Varsha

“…Two antigenically distinct influenza B lineages have co-circulated since the 1980s, yet inactivated trivalent influenza vaccines (TIVs) include strains of…”
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A review of the value of quadrivalent influenza vaccines and their potential contribution to influenza control by Ray, Riju, Dos Santos, Gaël, Buck, Philip O., Claeys, Carine, Matias, Gonçalo, Innis, Bruce L., Bekkat-Berkani, Rafik

“…The contribution of influenza B to the seasonal influenza burden varies from year-to-year. Although 2 antigenically distinct influenza B virus lineages have…”
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Immunogenicity and Safety of an Inactivated Quadrivalent Influenza Vaccine Candidate: A Phase III Randomized Controlled Trial in Children by Langley, Joanne M., Martinez, Alfonso Carmona, Chatterjee, Archana, Halperin, Scott A., McNeil, Shelly, Reisinger, Keith S., Aggarwal, Naresh, Huang, Li-Min, Peng, Ching-Tien, Garcia-Sicilia, José, de la Cueva, Ignacio Salamanca, Cabañas, Fernando, Treviño-Garza, Consuelo, Rodríguez-Weber, Miguel Angel, de la O, Manuel, Chandrasekaran, Vijayalakshmi, Dewé, Walthère, Liu, Aixue, Innis, Bruce L., Jain, Varsha K.

“…Background. Mismatch between circulating influenza B viruses (Yamagata and Victoria lineages) and vaccine strains occurs frequently. Methods. In a randomized…”
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Chimeric Hemagglutinin-Based Live-Attenuated Vaccines Confer Durable Protective Immunity against Influenza A Viruses in a Preclinical Ferret Model by Liu, Wen-Chun, Nachbagauer, Raffael, Stadlbauer, Daniel, Strohmeier, Shirin, Solórzano, Alicia, Berlanda-Scorza, Francesco, Innis, Bruce L, García-Sastre, Adolfo, Palese, Peter, Krammer, Florian, Albrecht, Randy A

“…Epidemic or pandemic influenza can annually cause significant morbidity and mortality in humans. We developed novel chimeric hemagglutinin (cHA)-based…”
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Efficacy of Inactivated Split-Virus Influenza Vaccine against Culture-Confirmed Influenza in Healthy Adults: A Prospective, Randomized, Placebo-Controlled Trial by Beran, Jiri, Vesikari, Timo, Wertzova, Veronika, Karvonen, Aino, Honegr, Karel, Lindblad, Niklas, Van Belle, Pascale, Peeters, Mathieu, Innis, Bruce L., Devaster, Jeanne-Marie

“…BackgroundA new trivalent inactivated split-virus influenza vaccine (TIV) was recently introduced in the United States. We assessed the efficacy of TIV against…”
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Dengue Viremia Titer, Antibody Response Pattern, and Virus Serotype Correlate with Disease Severity by Vaughn, David W., Green, Sharone, Kalayanarooj, Siripen, Innis, Bruce L., Nimmannitya, Suchitra, Suntayakorn, Saroj, Endy, Timothy P., Raengsakulrach, Boonyos, Rothman, Alan L., Ennis, Francis A., Nisalak, Ananda

“…Viremia titers in serial plasma samples from 168 children with acute dengue virus infection who were enrolled in a prospective study at 2 hospitals in Thailand…”
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Influenza A(H7N9) Pandemic Preparedness: Assessment of the Breadth of Heterologous Antibody Responses to Emerging Viruses from Multiple Pre-Pandemic Vaccines and Population Immunity by Levine, Min Z, Holiday, Crystal, Bai, Yaohui, Zhong, Weimin, Liu, Feng, Jefferson, Stacie, Gross, F. Liaini, Tzeng, Wen-pin, Fries, Louis, Smith, Gale, Boutet, Philippe, Friel, Damien, Innis, Bruce L, Mallett, Corey P, Davis, C. Todd, Wentworth, David E, York, Ian A, Stevens, James, Katz, Jacqueline M, Tumpey, Terrence

“…Influenza A(H7N9) viruses remain as a high pandemic threat. The continued evolution of the A(H7N9) viruses poses major challenges in pandemic preparedness…”
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AS03-adjuvanted H7N9 inactivated split virion vaccines induce cross-reactive and protective responses in ferrets by Stadlbauer, Daniel, Waal, Leon de, Beaulieu, Edith, Strohmeier, Shirin, Kroeze, Edwin J. B. Veldhuis, Boutet, Philippe, Osterhaus, Albert D. M. E., Krammer, Florian, Innis, Bruce L., Nachbagauer, Raffael, Stittelaar, Koert J., Mallett, Corey P.

“…Human infections with avian H7N9 subtype influenza viruses are a major public health concern and vaccines against H7N9 are urgently needed for pandemic…”
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Assessment of an optimized manufacturing process for inactivated quadrivalent influenza vaccine: a phase III, randomized, double-blind, safety and immunogenicity study in children and adults by Claeys, Carine, Drame, Mamadou, García-Sicilia, José, Zaman, Khalequ, Carmona, Alfonso, Tran, Phu My, Miranda, Mariano, Martinón-Torres, Federico, Thollot, Franck, Horn, Michael, Schwarz, Tino F, Behre, Ulrich, Merino, José M, Sadowska-Krawczenko, Iwona, Szymański, Henryk, Schu, Peter, Neumeier, Elisabeth, Li, Ping, Jain, Varsha K, Innis, Bruce L

“…GSK has modified the licensed monovalent bulk manufacturing process for its split-virion inactivated quadrivalent influenza vaccine (IIV4) to harmonize the…”
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Cell-mediated immune responses to different formulations of a live-attenuated tetravalent dengue vaccine candidate in subjects living in dengue endemic and non-endemic regions by Moris, Philippe, Bauer, Kristen M., Currier, Jeffrey R., Friberg, Heather, Eckels, Kenneth H., Esquilin, Ines O., Gibbons, Robert V., Innis, Bruce L., Jarman, Richard G., Simasathien, Sriluck, Sun, Peifang, Thomas, Stephen J., Watanaveeradej, Veerachai

“…Three phase II randomized trials evaluated the safety/immunogenicity of two formulations of live-attenuated tetravalent dengue virus (TDEN) vaccine in…”
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Phase I trial of 16 formulations of a tetravalent live-attenuated dengue vaccine by Edelman, Robert, Wasserman, Steven S, Bodison, Sacared A, Putnak, Robert J, Eckels, Kenneth H, Tang, Douglas, Kanesa-Thasan, Niranjan, Vaughn, David W, Innis, Bruce L, Sun, Wellington

“…Laboratory-attenuated strains of each of the four dengue serotypes previously tested as monovalent vaccines in volunteers were combined and tested for…”
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Phase 2 clinical trial of three formulations of tetravalent live-attenuated dengue vaccine in flavivirus-naïve adults by Sun, Wellington, Cunningham, Dennis, Wasserman, Steven S., Perry, Judith, Putnak, J. Robert, Eckels, Kenneth H., Vaughn, David W., Thomas, Stephen J., Kanesa-Thasan, Niranjan, Innis, Bruce L., Edelman, Robert

“…Sixteen dose formulations of our live-attenuated tetravalent dengue virus vaccines (TDV) were previously evaluated for safety and immunogenicity. Two of the…”
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