Search Results - "Inkster, James A. H."

Mitochondrial transplantation enhances murine lung viability and recovery after ischemia-reperfusion injury by Moskowitzova, Kamila, Orfany, Arzoo, Liu, Kaifeng, Ramirez-Barbieri, Giovanna, Thedsanamoorthy, Jerusha K, Yao, Rouan, Guariento, Alvise, Doulamis, Ilias P, Blitzer, David, Shin, Borami, Snay, Erin R, Inkster, James A H, Iken, Khadija, Packard, Alan B, Cowan, Douglas B, Visner, Gary A, Del Nido, Pedro J, McCully, James D

“…The most common cause of acute lung injury is ischemia-reperfusion injury (IRI), during which mitochondrial damage occurs. We have previously demonstrated that…”
Get more information

Magnetic Droplet Microfluidics as a Platform for the Concentration of [18F]Fluoride and Radiosynthesis of Sulfonyl [18F]Fluoride by Fiel, Somewhere A, Yang, Hua, Schaffer, Paul, Weng, Samuel, Inkster, James A. H, Wong, Michael C. K, Li, Paul C. H

“…The radioisotope 18F is often considered the best choice for positron emission tomography (PET) owing to its desirable chemical and radiochemical properties…”
Get full text

The Non-Anhydrous, Minimally Basic Synthesis of the Dopamine D2 Agonist [18F]MCL-524 by Inkster, James A. H., Sromek, Anna W., Akurathi, Vamsidhar, Neumeyer, John L., Packard, Alan B.

“…The dopamine D2 agonist MCL-524 is selective for the D2 receptor in the high-affinity state (D2high), and, therefore, the PET analogue, [18F]MCL-524, may…”
Get full text

Mitochondrial transplantation prolongs cold ischemia time in murine heart transplantation by Moskowitzova, Kamila, Shin, Borami, Liu, Kaifeng, Ramirez-Barbieri, Giovanna, Guariento, Alvise, Blitzer, David, Thedsanamoorthy, Jerusha K., Yao, Rouan, Snay, Erin R., Inkster, James A.H., Orfany, Arzoo, Zurakowski, David, Cowan, Douglas B., Packard, Alan B., Visner, Gary A., del Nido, Pedro J., McCully, James D.

“…Cold ischemia time (CIT) causes ischemia‒reperfusion injury to the mitochondria and detrimentally effects myocardial function and tissue viability…”
Get full text

Preclinical validations of [18F]FPyPEGCBT-c(RGDfK): a 18F-labelled RGD peptide prepared by ligation of 2-cyanobenzothiazole and 1,2-aminothiol to image angiogenesis by Colin, Didier J., Inkster, James A. H., Germain, Stéphane, Seimbille, Yann

“…Background α V β 3 , α V β 5 and α 5 β 1 integrins are known to be involved in carcinogenesis and are overexpressed in many types of tumours compared to…”
Get full text

Sulfonyl Fluoride-Based Prosthetic Compounds as Potential 18F Labelling Agents by Inkster, James A. H., Liu, Kate, Ait-Mohand, Samia, Schaffer, Paul, Guérin, Brigitte, Ruth, Thomas J., Storr, Tim

“…Nucleophilic incorporation of [18F]F− under aqueous conditions holds several advantages in radiopharmaceutical development, especially with the advent of…”
Get full text

The Non-Anhydrous, Minimally Basic Synthesis of the Dopamine D 2 Agonist [18F]MCL-524 by Inkster, James A H, Sromek, Anna W, Akurathi, Vamsidhar, Neumeyer, John L, Packard, Alan B

“…The dopamine D agonist MCL-524 is selective for the D receptor in the high-affinity state (D ), and, therefore, the PET analogue, [ F]MCL-524, may facilitate…”
Get full text

Labeling of an Antisense Oligonucleotide with [18F]FPy5yne by Inkster, James A. H., Adam, Michael J., Storr, Tim, Ruth, Thomas J.

“…Functional imaging of gene expression in vivo with short-lived positron emitter 18 F remains an unrealized goal, in part because the long reaction times and…”
Get full text

Radiosynthesis and bioconjugation of [18F]FPy5yne, a prosthetic group for the 18F labeling of bioactive peptides by Inkster, James A. H., Guérin, Brigitte, Ruth, Thomas J., Adam, Michael J.

“…A new 18F‐based prosthetic group has been prepared for the labeling of azide‐modified peptides for use in PET imaging. 2‐[18F]fluoro‐3‐(hex‐5‐ynyloxy)pyridine…”
Get full text

A novel 2-cyanobenzothiazole-based (18)F prosthetic group for conjugation to 1,2-aminothiol-bearing targeting vectors by Inkster, James A H, Colin, Didier J, Seimbille, Yann

“…In a bid to find an efficient means to radiolabel biomolecules under mild conditions for PET imaging, a bifunctional (18)F prosthetic molecule has been…”
Get more information

Sulfonyl Fluoride‐Based Prosthetic Compounds as Potential 18 F Labelling Agents by Inkster, James A. H., Liu, Kate, Ait‐Mohand, Samia, Schaffer, Paul, Guérin, Brigitte, Ruth, Thomas J., Storr, Tim

“…Nucleophilic incorporation of [ 18 F]F − under aqueous conditions holds several advantages in radiopharmaceutical development, especially with the advent of…”
Get full text

Preclinical validations of [ 18 F]FPyPEGCBT- c (RGDfK): a 18 F-labelled RGD peptide prepared by ligation of 2-cyanobenzothiazole and 1,2-aminothiol to image angiogenesis by Colin, Didier J, Inkster, James A H, Germain, Stéphane, Seimbille, Yann

“…α β , α β and α β integrins are known to be involved in carcinogenesis and are overexpressed in many types of tumours compared to healthy tissues; thereby they…”
Get full text

Sulfonyl Fluoride-Based Prosthetic Compounds as Potential super(18)F Labelling Agents by Inkster, James AH, Liu, Kate, Ait-Mohand, Samia, Schaffer, Paul, Guerin, Brigitte, Ruth, Thomas J, Storr, Tim

“…Nucleophilic incorporation of [ super(18)F]F super(-) under aqueous conditions holds several advantages in radiopharmaceutical development, especially with the…”
Get full text

Radiosynthesis and bioconjugation of [ 18 F]FPy5yne, a prosthetic group for the 18 F labeling of bioactive peptides by Inkster, James A. H., Guérin, Brigitte, Ruth, Thomas J., Adam, Michael J.

“…A new 18 F‐based prosthetic group has been prepared for the labeling of azide‐modified peptides for use in PET imaging. 2‐[ 18…”
Get full text