Search Results - "Inker, Lesley"

Measurement and Estimation of GFR for Use in Clinical Practice: Core Curriculum 2021 by Inker, Lesley A., Titan, Silvia

“…Assessment of glomerular filtration rate (GFR) is fundamental to clinical practice, public health, and research. The kidney has several critical functions; GFR…”
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GFR Estimation: From Physiology to Public Health by Levey, Andrew S., MD, Inker, Lesley A., MD, MS, Coresh, Josef, MD, MS, PhD

“…Estimating glomerular filtration rate (GFR) is essential for clinical practice, research, and public health. Appropriate interpretation of estimated GFR (eGFR)…”
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KDOQI US Commentary on the 2012 KDIGO Clinical Practice Guideline for the Evaluation and Management of CKD by Inker, Lesley A., MD, Astor, Brad C., PhD, Fox, Chester H., MD, Isakova, Tamara, MD, Lash, James P., MD, Peralta, Carmen A., MD, Kurella Tamura, Manjula, MD, Feldman, Harold I., MD, MSCE

“…The National Kidney Foundation–Kidney Disease Outcomes Quality Initiative (NKF-KDOQI) guideline for evaluation, classification, and stratification of chronic…”
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Measured and estimated glomerular filtration rate: current status and future directions by Levey, Andrew S., Coresh, Josef, Tighiouart, Hocine, Greene, Tom, Inker, Lesley A.

“…Evaluation of glomerular filtration rate (GFR) is central to the assessment of kidney function in medical practice, research and public health. Measured GFR…”
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GFR Decline as an End Point for Clinical Trials in CKD: A Scientific Workshop Sponsored by the National Kidney Foundation and the US Food and Drug Administration by Levey, Andrew S., MD, Inker, Lesley A., MD, MS, Matsushita, Kunihiro, MD, PhD, Greene, Tom, PhD, Willis, Kerry, PhD, Lewis, Edmund, MD, de Zeeuw, Dick, MD, PhD, Cheung, Alfred K., MD, Coresh, Josef, MD, PhD

“…The US Food and Drug Administration currently accepts halving of glomerular filtration rate (GFR), assessed as doubling of serum creatinine level, as a…”
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A Unifying Approach for GFR Estimation: Recommendations of the NKF-ASN Task Force on Reassessing the Inclusion of Race in Diagnosing Kidney Disease by Delgado, Cynthia, Baweja, Mukta, Crews, Deidra C., Eneanya, Nwamaka D., Gadegbeku, Crystal A., Inker, Lesley A., Mendu, Mallika L., Miller, W. Greg, Moxey-Mims, Marva M., Roberts, Glenda V., St. Peter, Wendy L., Warfield, Curtis, Powe, Neil R.

“…In response to a national call for re-evaluation of the use of race in clinical algorithms, the National Kidney Foundation (NKF) and the American Society of…”
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Uses of GFR and Albuminuria Level in Acute and Chronic Kidney Disease by Levey, Andrew S., Grams, Morgan E., Inker, Lesley A.

“…Testing for kidney disease is routine in clinical practice. This review focuses on advances in clinical evaluation of the glomerular filtration rate and…”
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Kidney Disease, Race, and GFR Estimation by Levey, Andrew S, Titan, Silvia M, Powe, Neil R, Coresh, Josef, Inker, Lesley A

“…Assessment of GFR is central to clinical practice, research, and public health. Current Kidney Disease Improving Global Outcomes guidelines recommend…”
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Glomerular Filtration Rate and Albuminuria for Detection and Staging of Acute and Chronic Kidney Disease in Adults: A Systematic Review by Levey, Andrew S, Becker, Cassandra, Inker, Lesley A

“…IMPORTANCE: Because early-stage kidney disease is asymptomatic and is associated with both morbidity and mortality, laboratory measurements are required for…”
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Serum Cystatin C for Estimation of GFR by Shlipak, Michael G, Inker, Lesley A, Coresh, Josef

“…An 80-year-old man with type 2 diabetes and hypertension was referred to the nephrology clinic for persistent hyperkalemia. The patient was frail and…”
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Estimation of Glomerular Filtration Rate With vs Without Including Patient Race by Levey, Andrew S, Tighiouart, Hocine, Titan, Silvia M, Inker, Lesley A

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GFR as the “Gold Standard”: Estimated, Measured, and True by Levey, Andrew S., MD, Inker, Lesley A., MD, MS

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GFR Slope as a Surrogate End Point for Kidney Disease Progression in Clinical Trials: A Meta-Analysis of Treatment Effects of Randomized Controlled Trials by Inker, Lesley A, Heerspink, Hiddo J L, Tighiouart, Hocine, Levey, Andrew S, Coresh, Josef, Gansevoort, Ron T, Simon, Andrew L, Ying, Jian, Beck, Gerald J, Wanner, Christoph, Floege, Jürgen, Li, Philip Kam-Tao, Perkovic, Vlado, Vonesh, Edward F, Greene, Tom

“…Surrogate end points are needed to assess whether treatments are effective in the early stages of CKD. GFR decline leads to kidney failure, but regulators have…”
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Chronic Kidney Disease in Older People by Levey, Andrew S, Inker, Lesley A, Coresh, Josef

“…Levey et al examine chronic kidney disease (CKD) in older people. CKD is a global public health problem, affecting more than 10% of the world's population and…”
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Proteinuria Reduction as a Surrogate End Point in Trials of IgA Nephropathy by Thompson, Aliza, Carroll, Kevin, A Inker, Lesley, Floege, Jürgen, Perkovic, Vlado, Boyer-Suavet, Sonia, W Major, Rupert, I Schimpf, Judith, Barratt, Jonathan, Cattran, Daniel C, S Gillespie, Barbara, Kausz, Annamaria, W Mercer, Alex, Reich, Heather N, H Rovin, Brad, West, Melissa, Nachman, Patrick H

“…IgA nephropathy (IgAN) is an important cause of ESKD for which there are no approved therapies. A challenge for evaluating treatments for IgAN is the usual…”
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Estimating Glomerular Filtration Rate from Serum Creatinine and Cystatin C by Inker, Lesley A, Schmid, Christopher H, Tighiouart, Hocine, Eckfeldt, John H, Feldman, Harold I, Greene, Tom, Kusek, John W, Manzi, Jane, Van Lente, Frederick, Zhang, Yaping Lucy, Coresh, Josef, Levey, Andrew S

“…This study presents an equation for estimating the glomerular filtration rate that uses both creatinine and cystatin C. It performs better than equations with…”
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Comparing Bayesian hierarchical meta-regression methods and evaluating the influence of priors for evaluations of surrogate endpoints on heterogeneous collections of clinical trials by Collier, Willem, Haaland, Benjamin, Inker, Lesley A, Heerspink, Hiddo J L, Greene, Tom

“…Surrogate endpoints, such as those of interest in chronic kidney disease (CKD), are often evaluated using Bayesian meta-regression. Trials used for the…”
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Change in Albuminuria and GFR as End Points for Clinical Trials in Early Stages of CKD: A Scientific Workshop Sponsored by the National Kidney Foundation in Collaboration With the US Food and Drug Administration and European Medicines Agency by Levey, Andrew S., Gansevoort, Ron T., Coresh, Josef, Inker, Lesley A., Heerspink, Hiddo L., Grams, Morgan E., Greene, Tom, Tighiouart, Hocine, Matsushita, Kunihiro, Ballew, Shoshana H., Sang, Yingying, Vonesh, Edward, Ying, Jian, Manley, Tom, de Zeeuw, Dick, Eckardt, Kai-Uwe, Levin, Adeera, Perkovic, Vlado, Zhang, Luxia, Willis, Kerry

“…The US Food and Drug Administration (FDA) and European Medicines Agency (EMA) are currently willing to consider a 30% to 40% glomerular filtration rate (GFR)…”
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"Should the definition of CKD be changed to include age-adapted GFR criteria?": Con: the evaluation and management of CKD, not the definition, should be age-adapted by Levey, Andrew S, Inker, Lesley A, Coresh, Josef

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In Search of a Better Equation — Performance and Equity in Estimates of Kidney Function by Diao, James A, Inker, Lesley A, Levey, Andrew S, Tighiouart, Hocine, Powe, Neil R, Manrai, Arjun K

“…Although many experts agree that we should reconsider the use of race in equations for estimated glomerular filtration rate and in medicine more generally,…”
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