Search Results - "Iniguez, Miguel A"

Regulation of Cyclooxygenase-2 Expression in Human T Cells by Glucocorticoid Receptor-Mediated Transrepression of Nuclear Factor of Activated T Cells by Cacheiro-Llaguno, Cristina, Hernández-Subirá, Elena, Díaz-Muñoz, Manuel D., Fresno, Manuel, Serrador, Juan M., Íñiguez, Miguel A.

“…Cyclooxygenase (COX) is the key enzyme in prostanoid synthesis from arachidonic acid (AA). Two isoforms, named COX-1 and COX-2, are expressed in mammalian…”
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Involvement of PGE2 and the cAMP signalling pathway in the up-regulation of COX-2 and mPGES-1 expression in LPS-activated macrophages by Díaz-Muñoz, Manuel D, Osma-García, Inés C, Fresno, Manuel, Iñiguez, Miguel A

“…PG (prostaglandin) E2 plays an important role in the modulation of the immune response and the inflammatory process. In the present study, we describe a PGE2…”
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Echolocation behavior of franciscana dolphins ( Pontoporia blainvillei ) in the wild by Melcón, Mariana L., Failla, Mauricio, Iñíguez, Miguel A.

“…Franciscana dolphins are small odontocetes hard to study in the field. In particular, little is known on their echolocation behavior in the wild. In this study…”
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Coordinated up-regulation of cyclooxygenase-2 and microsomal prostaglandin E synthase 1 transcription by nuclear factor kappa B and early growth response-1 in macrophages by Díaz-Muñoz, Manuel D., Osma-García, Inés C., Cacheiro-Llaguno, Cristina, Fresno, Manuel, Íñiguez, Miguel A.

“…Prostaglandin (PG) E2 is a potent lipid mediator that plays an essential role in inflammation, fever and pain. It is produced from arachidonic acid (AA) by a…”
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Inhibition of Hypoxia Inducible Factor-1α by Dihydroxyphenylethanol, a Product from Olive Oil, Blocks Microsomal Prostaglandin-E Synthase-1/Vascular Endothelial Growth Factor Expression and Reduces Tumor Angiogenesis by TERZUOLI, Erika, DONNINI, Sandra, GIACHETTI, Antonio, INIGUEZ, Miguel A, FRESNO, Manuel, MELILLO, Giovanni, ZICHE, Marina

“…Purpose: 2-(3,4-dihydroxyphenil)-ethanol (DPE), a polyphenol present in olive oil, has been found to attenuate the growth of colon cancer cells, an effect…”
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Nitric Oxide and Electrophilic Cyclopentenone Prostaglandins in Redox signaling, Regulation of Cytoskeleton Dynamics and Intercellular Communication by Bago, Ángel, Íñiguez, Miguel A., Serrador, Juan M.

“…Nitric oxide (NO) and electrophilic cyclopentenone prostaglandins (CyPG) are local mediators that modulate cellular response to oxidative stress in different…”
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Inhibition of lipopolysaccharide-induced gene expression by liver X receptor ligands in macrophages involves interference with early growth response factor 1 by Guillem-Llobat, Paloma, Íñiguez, Miguel A

“…Abstract Liver X receptors (LXRs) are nuclear receptors that act as ligand-dependent transcription factors forming permissive heterodimers with retinoid X…”
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Towards understanding the ontogeny of echolocation in franciscana dolphins (Pontoporia blainvillei) by Melcón, Mariana L., Failla, Mauricio, Iñíguez, Miguel A.

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Description and clustering of echolocation signals of Commerson's dolphins (Cephalorhynchus commersonii) in Bahía San Julián, Argentina by Reyes Reyes, M Vanesa, Iñíguez, Miguel A, Hevia, Marta, Hildebrand, John A, Melcón, Mariana L

“…Commerson's dolphins (Cephalorhynchus commersonii) inhabit coastal waters of Southern South America and Kerguelen Islands. Limited information exists about the…”
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Prostanoid signal transduction and gene expression in the endothelium : Role in cardiovascular diseases by ALFRANCA, Arantzazu, INIGUEZ, Miguel A, FRESNO, Manuel, REDONDO, Juan Miguel

“…Endothelial cells play an active role in the maintenance of homeostasis. Endothelial injury can give rise to endothelial dysfunction in which the profile of…”
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Communication sounds of Commerson's dolphins (Cephalorhynchus commersonii) and contextual use of vocalizations by Reyes Reyes, M. Vanesa, Tossenberger, Vanesa P., Iñiguez, Miguel A., Hildebrand, John A., Melcón, Mariana L.

“…Cetaceans produce a variety of vocalizations to communicate; however, little information exists on the acoustic behavior displayed by Commerson's dolphins…”
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Cyclooxygenase-2 deficiency in macrophages leads to defective p110γ PI3K signaling and impairs cell adhesion and migration by Díaz-Muñoz, Manuel D, Osma-García, Inés C, Iñiguez, Miguel A, Fresno, Manuel

“…Cyclooxygenase (Cox)-2 dependent PGs modulate several functions in many pathophysiological processes, including migration of immune cells. In this study, we…”
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Induction of Cyclooxygenase-2 on Activated T Lymphocytes: Regulation of T Cell Activation by Cyclooxygenase-2 Inhibitors by Iniguez, Miguel A, Punzon, Carmen, Fresno, Manuel

“…Cyclooxygenase (COX), known to exist in two isoforms, COX-1 and COX-2, is a key enzyme in prostaglandin synthesis and the target for most nonsteroidal…”
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Inhibitory effects of sigma-2 receptor agonists on T lymphocyte activation by Iñiguez, Miguel A, Punzón, Carmen, Nieto, Raquel, Burgueño, Javier, Vela, José M, Fresno, Manuel

“…Sigma (σ) receptor ligands are essentially known for their effects on the nervous system although recent studies have shown their potential effects modulating…”
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Nitro-oleic acid regulates T cell activation through post-translational modification of calcineurin by Bago, Ángel, Cayuela, M Laura, Gil, Alba, Calvo, Enrique, Vázquez, Jesús, Queiro, Antonio, Schopfer, Francisco J, Radi, Rafael, Serrador, Juan M, Íñiguez, Miguel A

“…Nitro-fatty acids (NO -FAs) are unsaturated fatty acid nitration products that exhibit anti-inflammatory actions in experimental mouse models of autoimmune and…”
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Cyclooxygenase-2 and Prostaglandin E2 Signaling through Prostaglandin Receptor EP-2 Favor the Development of Myocarditis during Acute Trypanosoma cruzi Infection by Guerrero, Néstor A, Camacho, Mercedes, Vila, Luis, Íñiguez, Miguel A, Chillón-Marinas, Carlos, Cuervo, Henar, Poveda, Cristina, Fresno, Manuel, Gironès, Núria

“…Inflammation plays an important role in the pathophysiology of Chagas disease, caused by Trypanosoma cruzi. Prostanoids are regulators of homeostasis and…”
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Expression and function of the nuclear factor of activated T cells in colon carcinoma cells: involvement in the regulation of cyclooxygenase-2 by Duque, Javier, Fresno, Manuel, Iñiguez, Miguel A

“…Increasing evidence shows a crucial role of the Ca2+/ calcineurin-mediated activation of the nuclear factor of activated T cells (NFAT) in the regulation of a…”
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Peroxisome-proliferator-activated receptor alpha agonists inhibit cyclo-oxygenase 2 and vascular endothelial growth factor transcriptional activation in human colorectal carcinoma cells via inhibition of activator protein-1 by Grau, Raquel, Punzón, Carmen, Fresno, Manuel, Iñiguez, Miguel A

“…Recent evidence indicates that PPAR (peroxisome-proliferator-activated receptor) alpha ligands possess anti-inflammatory and antitumoural properties owing to…”
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Up-regulation of cyclooxygenase-2 by interleukin-1β in colon carcinoma cells by Duque, Javier, Díaz-Muñoz, Manuel D., Fresno, Manuel, Iñiguez, Miguel A.

“…Growing evidence shows that Interleukin (IL)-1β and Cyclooxygenase 2 (COX-2) play a crucial role in the pathogenesis of inflammatory diseases and tumor growth,…”
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The hepatitis B virus X protein promotes tumor cell invasion by inducing membrane-type matrix metalloproteinase-1 and cyclooxygenase-2 expression by Lara-Pezzi, Enrique, Gómez-Gaviro, Maria Victoria, Gálvez, Beatriz G, Mira, Emilia, Iñiguez, Miguel A, Fresno, Manuel, Martínez-A, Carlos, Arroyo, Alicia G, López-Cabrera, Manuel

“…Hepatocellular carcinoma is strongly associated with chronic infection by the hepatitis B virus (HBV) and has poor prognosis due to intrahepatic metastasis…”
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