Search Results - "Iniguez, Abdon"
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Predictive nonlinear modeling of malignant myelopoiesis and tyrosine kinase inhibitor therapy
Published in eLife (28-04-2023)“…Chronic myeloid leukemia (CML) is a blood cancer characterized by dysregulated production of maturing myeloid cells driven by the product of the Philadelphia…”
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Journal Article -
2
Spatial pattern formation in microtubule post-translational modifications and the tight localization of motor-driven cargo
Published in Journal of mathematical biology (01-04-2017)“…Microtubule (MT) “age” can be interpreted as nucleotide state, lattice defects, or post-translational modification (PTM) such as acetylation and…”
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Journal Article -
3
Timing of CD8 T cell effector responses in viral infections
Published in Royal Society open science (01-02-2016)“…CD8 T cell or cytotoxic T lymphocyte (CTL) responses are an important branch of the immune system in the fight against viral infections. The dynamics of…”
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Journal Article -
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Post-Translational Modification in Microtubule Arrays Exhibits Spatial Patterns that can act as a Signal to Tightly Localize Motor-Driven Cargo
Published in Biophysical journal (16-02-2016)Get full text
Journal Article -
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Mathematical Modeling of Malignant Myelopoiesis: Optimal Experimental Design and Targeted Therapy
Published 01-01-2019“…Chronic myeloid leukemia (CML) is a blood cancer in which there is dysregulation of maturing myeloid cells (granulocytes) driven by a chromosomal mutation…”
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Dissertation -
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Optimal experimental design for mathematical models of haematopoiesis
Published in Journal of the Royal Society interface (01-01-2021)“…The haematopoietic system has a highly regulated and complex structure in which cells are organized to successfully create and maintain new blood cells. It is…”
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Journal Article -
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Optimal Experimental Design for Mathematical Models of Hematopoiesis
Published 20-04-2020“…The hematopoietic system has a highly regulated and complex structure in which cells are organized to successfully create and maintain new blood cells…”
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Journal Article