Search Results - "Ingles, Natasha N"
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Targeting YES1 Disrupts Mitotic Fidelity and Potentiates the Response to Taxanes in Triple-Negative Breast Cancer
Published in Cancer research (Chicago, Ill.) (04-11-2024)“…Clinical trials examining broad-spectrum Src family kinase (SFK) inhibitors revealed significant dose-limiting toxicities, preventing advancement for solid…”
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The transcriptional repressor BCL11A promotes breast cancer metastasis
Published in The Journal of biological chemistry (14-08-2020)“…The phenotypes of each breast cancer subtype are defined by their transcriptomes. However, the transcription factors that regulate differential patterns of…”
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Abstract 172: BCL11A regulation of extracellular matrix genes may be necessary for invasion of triple-negative breast cancer
Published in Cancer research (Chicago, Ill.) (01-07-2019)“…Abstract Triple-negative breast cancer (TNBC) represents 15% of all breast cancers, yet conveys the poorest patient prognoses due to the lack of targeted…”
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Abstract 32: BCL11A is necessary for the expression of extracellular matrix genes and metastatic progression of triple-negative breast cancer
Published in Cancer research (Chicago, Ill.) (01-07-2018)“…Abstract Cancer stem cells (CSC) contribute to the high incidence of metastatic recurrence in triple-negative breast cancer (TNBC) and elucidating the…”
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