Search Results - "Ingerman, Elena"

Chemical Inhibition of the Mitochondrial Division Dynamin Reveals Its Role in Bax/Bak-Dependent Mitochondrial Outer Membrane Permeabilization by Cassidy-Stone, Ann, Chipuk, Jerry E., Ingerman, Elena, Song, Cheng, Yoo, Choong, Kuwana, Tomomi, Kurth, Mark J., Shaw, Jared T., Hinshaw, Jenny E., Green, Douglas R., Nunnari, Jodi

“…Mitochondrial fusion and division play important roles in the regulation of apoptosis. Mitochondrial fusion proteins attenuate apoptosis by inhibiting release…”
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Conformational changes in Dnm1 support a contractile mechanism for mitochondrial fission by Hinshaw, Jenny E, Mears, Jason A, Lackner, Laura L, Fang, Shunming, Ingerman, Elena, Nunnari, Jodi

“…Mitochondria go through cycles of fusion and fission. The yeast dynamin-related protein, Dnm1, localizes to sites of membrane fission and fusion. Hinshaw and…”
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A Post-Transcriptional Feedback Mechanism for Noise Suppression and Fate Stabilization by Hansen, Maike M.K., Wen, Winnie Y., Ingerman, Elena, Razooky, Brandon S., Thompson, Cassandra E., Dar, Roy D., Chin, Charles W., Simpson, Michael L., Weinberger, Leor S.

“…Diverse biological systems utilize fluctuations (“noise”) in gene expression to drive lineage-commitment decisions. However, once a commitment is made, noise…”
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Mdv1 Interacts with Assembled Dnm1 to Promote Mitochondrial Division by Naylor, Kari, Ingerman, Elena, Okreglak, Voytek, Marino, Michael, Hinshaw, Jenny E., Nunnari, Jodi

“…The dynamin-related GTPase, Dnm1, self-assembles into punctate structures that are targeted to the outer mitochondrial membrane where they mediate…”
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Arp2/3 complex ATP hydrolysis promotes lamellipodial actin network disassembly but is dispensable for assembly by Ingerman, Elena, Hsiao, Jennifer Ying, Mullins, R Dyche

“…We examined the role of ATP hydrolysis by the Arp2/3 complex in building the leading edge of a cell by studying the effects of hydrolysis defects on the…”
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Dnm1 forms spirals that are structurally tailored to fit mitochondria by Ingerman, Elena, Perkins, Edward M, Marino, Michael, Mears, Jason A, McCaffery, J. Michael, Hinshaw, Jenny E, Nunnari, Jodi

“…Dynamin-related proteins (DRPs) are large self-assembling GTPases whose common function is to regulate membrane dynamics in a variety of cellular processes…”
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A continuous, regenerative coupled GTPase assay for dynamin-related proteins by Ingerman, Elena, Nunnari, Jodi

“…Dynamin-related proteins (DRPs) compose a diverse family of proteins that function, through GTPase stimulated self-assembly, to remodel cellular membranes. The…”
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Article: Chemical Inhibition of the Mitochondrial Division Dynamin Reveals Its Role in Bax/Bak-Dependent Mitochondrial Outer Membrane Permeabilization by Cassidy-Stone, Ann, Chipuk, Jerry E, Ingerman, Elena, Song, Cheng, Yoo, Choong, Kuwana, Tomomi, Kurth, Mark J, Shaw, Jared T, Hinshaw, Jenny E, Green, Douglas R, Nunnari, Jodi

“…Mitochondrial fusion and division play important roles in the regulation of apoptosis. Mitochondrial fusion proteins attenuate apoptosis by inhibiting release…”
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The role of the dynamin-related GTPase, Dnm1, in mitochondrial division by Ingerman, Elena

“…Dynamin-related proteins (DRPs) are large self-assembling GTPases whose common function is to regulate membrane dynamics in a variety of cellular processes…”
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In Vitro Assays for Mitochondrial Fusion and Division by Ingerman, Elena, Meeusen, Shelly, DeVay, Rachel, Nunnari, Jodi

“…This chapter outlines two methods that have proved instrumental in recapitulating events in vitro assay that occur during mitochondrial division and fusion and…”
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