Search Results - "Ingato, Dominique"
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Good things come in small packages: Overcoming challenges to harness extracellular vesicles for therapeutic delivery
Published in Journal of controlled release (10-11-2016)“…Extracellular vesicles (EVs) hold great promise as potential therapeutic carriers. EVs are biologically active, intrinsically transporting cargo between cells…”
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Journal Article -
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Stimuli-disassembling gold nanoclusters for diagnosis of early stage oral cancer by optical coherence tomography
Published in Nano convergence (26-01-2018)“…A key design consideration in developing contrast agents is obtaining distinct, multiple signal changes in diseased tissue. Plasmonic gold nanoparticles (Au…”
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Journal Article -
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Cancer Cell-Derived, Drug-Loaded Nanovesicles Induced by Sulfhydryl-Blocking for Effective and Safe Cancer Therapy
Published in ACS nano (25-09-2018)“…Extracellular vesicles (EVs) pose great promise as therapeutic carriers due to their ideal size range and intrinsic biocompatibility. Limited scalability, poor…”
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Journal Article -
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Aqueous-Soluble, Acid-Transforming Chitosan for Efficient and Stimuli-Responsive Gene Silencing
Published in Biomacromolecules (14-05-2018)“…Despite its promises for biomedical applications, the lack of solubility in a physiological solution, the limited molecular interactions with nucleic acids due…”
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Journal Article -
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Viral/Nonviral Chimeric Nanoparticles To Synergistically Suppress Leukemia Proliferation via Simultaneous Gene Transduction and Silencing
Published in ACS nano (27-09-2016)“…Single modal cancer therapy that targets one pathological pathway often turns out to be inefficient. For example, relapse of chronic myelogenous leukemia (CML)…”
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Cell‐Free, Dendritic Cell‐Mimicking Extracellular Blebs for Molecularly Controlled Vaccination
Published in Advanced therapeutics (01-01-2023)“…Dendritic cells (DCs) are prime targets for vaccination and immunotherapy. However, limited control over antigen presentation at a desired maturation status in…”
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Journal Article -
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Chemically-Induced Extracellular Blebs for Versatile Cancer Therapy
Published 01-01-2018“…Extracellular vesicles (EVs) have recently gained momentum in the field of therapeutic delivery due to their promise as therapeutic carriers. Biomolecules are…”
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Dissertation -
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Chemotherapeutic-loaded extracellular nano-vesicles produced via sulfhydryl blocking
Published in Journal of extracellular vesicles (01-01-2018)“…Background: Extracellular vesicles (EVs) have great potential as therapeutic carriers as they are expected to exhibit high levels of biocompatibility and to…”
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Journal Article