Search Results - "Ingalls, Robin"

Complement alone drives efficacy of a chimeric antigonococcal monoclonal antibody by Gulati, Sunita, Beurskens, Frank J, de Kreuk, Bart-Jan, Roza, Marcel, Zheng, Bo, DeOliveira, Rosane B, Shaughnessy, Jutamas, Nowak, Nancy A, Taylor, Ronald P, Botto, Marina, He, Xianbao, Ingalls, Robin R, Woodruff, Trent M, Song, Wen-Chao, Schuurman, Janine, Rice, Peter A, Ram, Sanjay

“…Multidrug-resistant Neisseria gonorrhoeae is a global health problem. Monoclonal antibody (mAb) 2C7 recognizes a gonococcal lipooligosaccharide epitope that is…”
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Inflammation and fibrosis during Chlamydia pneumoniae infection is regulated by IL-1 and the NLRP3/ASC inflammasome by He, Xianbao, Mekasha, Samrawit, Mavrogiorgos, Nikolaos, Fitzgerald, Katherine A, Lien, Egil, Ingalls, Robin R

“…Chlamydia pneumoniae is a common respiratory pathogen associated with atypical pneumonia, and it has been suggested as a trigger or promoter of several chronic…”
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Killing of diverse eye pathogens (Acanthamoeba spp., Fusarium solani, and Chlamydia trachomatis) with alcohols by Aqeel, Yousuf, Rodriguez, Raquel, Chatterjee, Aparajita, Ingalls, Robin R, Samuelson, John

“…Blindness is caused by eye pathogens that include a free-living protist (Acanthamoeba castellanii, A. byersi, and/or other Acanthamoeba spp.), a fungus…”
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Differential expression of toll-like receptors in the human placenta across early gestation by Pudney, Jeffrey, He, Xianbao, Masheeb, Zahrah, Kindelberger, David W, Kuohung, Wendy, Ingalls, Robin R

“…Abstract Toll-like receptors (TLRs) are an essential component of the innate immune system. While a number of studies have described TLR expression in the…”
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Plasmid-Deficient Chlamydia muridarum Fail to Induce Immune Pathology and Protect against Oviduct Disease by O'Connell, Catherine M, Ingalls, Robin R, Andrews, Charles W., Jr, Scurlock, Amy M, Darville, Toni

“…Chlamydia trachomatis is the most prevalent sexually transmitted bacterial infection in the world. In women, genital infection can cause endometritis and…”
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Sexually Transmitted Infections in Pregnancy and Reproductive Health: Proceedings of the STAR Sexually Transmitted Infection Clinical Trial Group Programmatic Meeting by Wynn, Adriane, Bristow, Claire C., Cristillo, Anthony D., Murphy, Sara McCurdy, van den Broek, Nynke, Muzny, Christina, Kallapur, Suhas, Cohen, Craig, Ingalls, Robin R., Wiesenfeld, Harold, Litch, James A., Morris, Sheldon R., Klausner, Jeffrey D.

“…ABSTRACTThe goal of the STAR Sexually Transmitted Infection Clinical Trial Group (STI CTG) Programmatic meeting on Sexually Transmitted Infections (STIs) in…”
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Toll-like receptors by Lien, Egil, Ingalls, Robin R

“…The ability of a host to sense invasion by pathogenic organisms and to respond appropriately to control infection is paramount to survival. In the case of…”
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Distinct roles for dietary lipids and Porphyromonas gingivalis infection on atherosclerosis progression and the gut microbiota by Kramer, Carolyn D., Simas, Alexandra M., He, Xianbao, Ingalls, Robin R., Weinberg, Ellen O., Genco, Caroline Attardo

“…Mounting evidence in humans supports an etiological role for the microbiota in inflammatory atherosclerosis. Atherosclerosis is a progressive disease…”
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Performance of three screening tools to predict COVID-19 positivity in emergency department patients by DiLorenzo, Madeline A, Davis, Megan R, Dugas, Julianne N, Nelson, Kerrie P, Hochberg, Natasha S, Ingalls, Robin R, Mishuris, Rebecca Grochow, Schechter-Perkins, Elissa M

“…COVID-19 symptoms vary widely. This retrospective study assessed which of three clinical screening tools-a nursing triage screen (NTS), an ED review of systems…”
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CD14 cooperates with complement receptor 3 to mediate MyD88-independent phagocytosis of Borrelia burgdorferi by Hawley, Kelly L, Olson, Chris M., Jr, Iglesias-Pedraz, Juan M, Navasa, Nicolás, Cervantes, Jorge L, Caimano, Melissa J, Izadi, Hooman, Ingalls, Robin R, Pal, Utpal, Salazar, Juan C, Radolf, Justin D, Anguita, Juan

“…Phagocytosis of Borrelia burgdorferi, the causative agent of Lyme disease, is a poorly understood process, despite its importance during the host immune…”
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The sst1 resistance locus regulates evasion of type I interferon signaling by Chlamydia pneumoniae as a disease tolerance mechanism by He, Xianbao, Berland, Robert, Mekasha, Samrawit, Christensen, Thomas G, Alroy, Joseph, Kramnik, Igor, Ingalls, Robin R

“…The sst1, "supersusceptibility to tuberculosis," locus has previously been shown to be a genetic determinant of host resistance to infection with the…”
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Activation of NOD receptors by Neisseria gonorrhoeae modulates the innate immune response by Mavrogiorgos, Nikolaos, Mekasha, Samrawit, Yang, Yibin, Kelliher, Michelle A, Ingalls, Robin R

“…NOD1 and NOD2 are members of the NOD-like receptor family of cytosolic pattern recognition receptors that recognize specific fragments of the bacterial cell…”
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Specific Inflammatory Stimuli Lead to Distinct Platelet Responses in Mice and Humans by Beaulieu, Lea M, Clancy, Lauren, Tanriverdi, Kahraman, Benjamin, Emelia J, Kramer, Carolyn D, Weinberg, Ellen O, He, Xianbao, Mekasha, Samrawit, Mick, Eric, Ingalls, Robin R, Genco, Caroline A, Freedman, Jane E

“…Diverse and multi-factorial processes contribute to the progression of cardiovascular disease. These processes affect cells involved in the development of this…”
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Enhanced virulence of Chlamydia muridarum respiratory infections in the absence of TLR2 activation by He, Xianbao, Nair, Anjali, Mekasha, Samrawit, Alroy, Joseph, O'Connell, Catherine M, Ingalls, Robin R

“…Chlamydia trachomatis is a common sexually transmitted pathogen and is associated with infant pneumonia. Data from the female mouse model of genital tract…”
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Mouse Strain-Dependent Differences in Susceptibility to Neisseria gonorrhoeae Infection and Induction of Innate Immune Responses by Packiam, Mathanraj, Veit, Sandra J, Anderson, Deborah J, Ingalls, Robin R, Jerse, Ann E

“…Acute gonorrhea in women is characterized by a mucopurulent exudate that contains polymorphonuclear leukocytes (PMNs) with intracellular gonococci…”
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Plasmid-cured Chlamydia caviae activates TLR2-dependent signaling and retains virulence in the guinea pig model of genital tract infection by Frazer, Lauren C, Darville, Toni, Chandra-Kuntal, Kumar, Andrews, Jr, Charles W, Zurenski, Matthew, Mintus, Margaret, AbdelRahman, Yasser M, Belland, Robert J, Ingalls, Robin R, O'Connell, Catherine M

“…Loss of the conserved "cryptic" plasmid from C. trachomatis and C. muridarum is pleiotropic, resulting in reduced innate inflammatory activation via TLR2,…”
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Weekly SARS-CoV-2 screening of asymptomatic kindergarten to grade 12 students and staff helps inform strategies for safer in-person learning by Doron, Shira, Ingalls, Robin R., Beauchamp, Anne, Boehm, Jesse S., Boucher, Helen W., Chow, Linda H., Corridan, Linda, Goehringer, Katey, Golenbock, Doug, Larsen, Liz, Lussier, David, Testa, Marcia, Ciaranello, Andrea

“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission in K–12 schools was rare during in 2020–2021; few studies included Centers for…”
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Signaling events in pathogen-induced macrophage foam cell formation by Shaik-Dasthagirisaheb, Yazdani B., Mekasha, Samrawit, He, Xianbao, Gibson, Frank C., Ingalls, Robin R.

“…Macrophage foam cell formation is a key event in atherosclerosis. Several triggers induce low-density lipoprotein (LDL) uptake by macrophages to create foam…”
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Innate Immunity at the Mucosal Surface: Role of Toll-Like Receptor 3 and Toll-Like Receptor 9 in Cervical Epithelial Cell Responses to Microbial Pathogens by ANDERSEN, Jorunn M, AL-KHAIRY, Dina, INGALLS, Robin R

“…Toll-like receptors (TLRs) are a family of pattern recognition receptors that recognize distinct molecular patterns shared by a broad range of pathogens,…”
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Species-specific differences in regulation of macrophage inflammation by the C3a–C3a receptor axis by Ray, Tathagat Dutta, Mekasha, Samrawit, Liang, Yanmei, Lu, Bao, Ram, Sanjay, Ingalls, Robin R

“…Complement is an important arm of the innate immune system. Recent studies have shown that products of complement pathway activation can interact directly with…”
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