Search Results - "Ingalls, R."
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Biomass supply chain design and analysis: Basis, overview, modeling, challenges, and future
Published in Renewable & sustainable energy reviews (01-08-2013)“…Biofuels are identified as the potential solution for depleting fossil fuel reserves, increasing oil prices, and providing a clean, renewable energy source…”
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Complement alone drives efficacy of a chimeric antigonococcal monoclonal antibody
Published in PLoS biology (19-06-2019)“…Multidrug-resistant Neisseria gonorrhoeae is a global health problem. Monoclonal antibody (mAb) 2C7 recognizes a gonococcal lipooligosaccharide epitope that is…”
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3
Differential expression of toll-like receptors in the human placenta across early gestation
Published in Placenta (Eastbourne) (01-10-2016)“…Abstract Toll-like receptors (TLRs) are an essential component of the innate immune system. While a number of studies have described TLR expression in the…”
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Cutting edge: recognition of Gram-positive bacterial cell wall components by the innate immune system occurs via Toll-like receptor 2
Published in The Journal of immunology (1950) (01-07-1999)“…Invasive infection with Gram-positive and Gram-negative bacteria often results in septic shock and death. The basis for the earliest steps in innate immune…”
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Toll-like receptors
Published in Critical care medicine (01-01-2002)“…The ability of a host to sense invasion by pathogenic organisms and to respond appropriately to control infection is paramount to survival. In the case of…”
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Killing of diverse eye pathogens (Acanthamoeba spp., Fusarium solani, and Chlamydia trachomatis) with alcohols
Published in PLoS neglected tropical diseases (01-02-2017)“…Blindness is caused by eye pathogens that include a free-living protist (Acanthamoeba castellanii, A. byersi, and/or other Acanthamoeba spp.), a fungus…”
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Toll-like Receptor 2 Functions as a Pattern Recognition Receptor for Diverse Bacterial Products
Published in The Journal of biological chemistry (19-11-1999)“…Toll-like receptors (TLRs) 2 and 4 are signal transducers for lipopolysaccharide, the major proinflammatory constituent in the outer membrane of Gram-negative…”
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Toll-like receptor 4 imparts ligand-specific recognition of bacterial lipopolysaccharide
Published in The Journal of clinical investigation (15-02-2000)“…Lipopolysaccharide (LPS) is the main inducer of shock and death in Gram-negative sepsis. Recent evidence suggests that LPS-induced signal transduction begins…”
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Distinct roles for dietary lipids and Porphyromonas gingivalis infection on atherosclerosis progression and the gut microbiota
Published in Anaerobe (01-06-2017)“…Mounting evidence in humans supports an etiological role for the microbiota in inflammatory atherosclerosis. Atherosclerosis is a progressive disease…”
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Innate Immunity at the Mucosal Surface: Role of Toll-Like Receptor 3 and Toll-Like Receptor 9 in Cervical Epithelial Cell Responses to Microbial Pathogens
Published in Biology of reproduction (01-05-2006)“…Toll-like receptors (TLRs) are a family of pattern recognition receptors that recognize distinct molecular patterns shared by a broad range of pathogens,…”
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CD14 cooperates with complement receptor 3 to mediate MyD88-independent phagocytosis of Borrelia burgdorferi
Published in Proceedings of the National Academy of Sciences - PNAS (24-01-2012)“…Phagocytosis of Borrelia burgdorferi, the causative agent of Lyme disease, is a poorly understood process, despite its importance during the host immune…”
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Divergent Response to LPS and Bacteria in CD14-Deficient Murine Macrophages
Published in The Journal of immunology (1950) (15-10-2000)“…Gram-negative bacteria and the LPS constituent of their outer membranes stimulate the release of inflammatory mediators believed to be responsible for the…”
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Mouse Strain-Dependent Differences in Susceptibility to Neisseria gonorrhoeae Infection and Induction of Innate Immune Responses
Published in Infection and Immunity (01-01-2010)“…Acute gonorrhea in women is characterized by a mucopurulent exudate that contains polymorphonuclear leukocytes (PMNs) with intracellular gonococci…”
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Weekly SARS-CoV-2 screening of asymptomatic kindergarten to grade 12 students and staff helps inform strategies for safer in-person learning
Published in Cell reports. Medicine (16-11-2021)“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission in K–12 schools was rare during in 2020–2021; few studies included Centers for…”
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Response to Neisseria gonorrhoeae by Cervicovaginal Epithelial Cells Occurs in the Absence of Toll-Like Receptor 4-Mediated Signaling
Published in The Journal of immunology (1950) (01-03-2002)“…Toll-like receptors (TLRs) have recently been identified as fundamental components of the innate immune response to bacterial pathogens. We investigated the…”
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Strongyloides stercoralis Transmission by Kidney Transplantation in Two Recipients From a Common Donor
Published in American journal of transplantation (01-09-2013)“…Strongyloides stercoralis hyperinfection in an immunocompromised host has a high mortality rate but may initially present with nonspecific pulmonary and…”
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Chlamydia trachomatis Infection, when Treated during Pregnancy, Is Not Associated with Preterm Birth in an Urban Safety-Net Hospital
Published in Infectious diseases in obstetrics and gynecology (2020)“…Preterm birth is a major public health problem, occurring in more than half a million births per year in the United States. A number of maternal conditions…”
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CD11c/CD18, a transmembrane signaling receptor for lipopolysaccharide
Published in The Journal of experimental medicine (01-04-1995)“…CD11c/CD18 is a member of the leukocyte integrin family, heterodimeric adhesion molecules that interact with a diverse repertoire of ligands, including…”
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Fournier’s gangrene as an initial manifestation of acute promyelocytic leukemia: A case report and review of the literature
Published in SAGE open medical case reports (2019)“…Fournier’s gangrene is classically associated with diabetes mellitus and alcohol use disorder. While it is associated with chemotherapy, there are few case…”
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The sst1 resistance locus regulates evasion of type I interferon signaling by Chlamydia pneumoniae as a disease tolerance mechanism
Published in PLoS pathogens (01-08-2013)“…The sst1, "supersusceptibility to tuberculosis," locus has previously been shown to be a genetic determinant of host resistance to infection with the…”
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