Search Results - "Inflammation and regeneration"

How COVID-19 induces cytokine storm with high mortality by Hojyo, Shintaro, Uchida, Mona, Tanaka, Kumiko, Hasebe, Rie, Tanaka, Yuki, Murakami, Masaaki, Hirano, Toshio

“…The newly emerging coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was first reported in Wuhan,…”
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The role of interleukin-1 in general pathology by Kaneko, Naoe, Kurata, Mie, Yamamoto, Toshihiro, Morikawa, Shinnosuke, Masumoto, Junya

“…Interleukin-1, an inflammatory cytokine, is considered to have diverse physiological functions and pathological significances and play an important role in…”
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RANKL biology: bone metabolism, the immune system, and beyond by Ono, Takehito, Hayashi, Mikihito, Sasaki, Fumiyuki, Nakashima, Tomoki

“…Receptor activator of NF-κB (RANK) ligand (RANKL) induces the differentiation of monocyte/macrophage-lineage cells into the bone-resorbing cells called…”
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Piezoelectric smart biomaterials for bone and cartilage tissue engineering by Jacob, Jaicy, More, Namdev, Kalia, Kiran, Kapusetti, Govinda

“…Tissues like bone and cartilage are remodeled dynamically for their functional requirements by signaling pathways. The signals are controlled by the cells and…”
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Maintenance of intestinal homeostasis by mucosal barriers by Okumura, Ryu, Takeda, Kiyoshi

“…The intestine is inhabited by a tremendous number of microorganisms, which provide many benefits to nutrition, metabolism and immunity. Mucosal barriers by…”
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The roles and mechanisms of senescence-associated secretory phenotype (SASP): can it be controlled by senolysis? by Ohtani, Naoko

“…Cellular senescence is a state of irreversible cell cycle arrest that can be induced by a variety of potentially oncogenic stimuli, including DNA damage…”
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Macrophage activation syndrome and COVID-19 by Otsuka, Ryo, Seino, Ken-Ichiro

“…An emerging, rapidly spreading coronavirus SARS-CoV-2 is causing a devastating pandemic. As we have not developed curative medicine and effective vaccine, the…”
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Endocannabinoids and related N -acylethanolamines: biological activities and metabolism by Tsuboi, Kazuhito, Uyama, Toru, Okamoto, Yasuo, Ueda, Natsuo

“…The plant contains cannabinoids represented by Δ -tetrahydrocannabinol, which exert psychoactivity and immunomodulation through cannabinoid CB1 and CB2…”
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Accelerating skin regeneration and wound healing by controlled ROS from photodynamic treatment by Khorsandi, Khatereh, Hosseinzadeh, Reza, Esfahani, HomaSadat, Zandsalimi, Kavosh, Shahidi, Fedora Khatibi, Abrahamse, Heidi

“…Cellular metabolisms produce reactive oxygen species (ROS) which are essential for cellular signaling pathways and physiological functions. Nevertheless, ROS…”
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Overview: an iPS cell stock at CiRA by Umekage, Masafumi, Sato, Yoshiko, Takasu, Naoko

“…Induced pluripotent stem cells (iPSCs) can be produced from various somatic cells and have the ability to differentiate into various cells and tissues of the…”
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Mesenchymal stem cell therapies for liver cirrhosis: MSCs as "conducting cells" for improvement of liver fibrosis and regeneration by Tsuchiya, Atsunori, Takeuchi, Suguru, Watanabe, Takayuki, Yoshida, Tomoaki, Nojiri, Shunsuke, Ogawa, Masahiro, Terai, Shuji

“…Mesenchymal stem cells (MSCs) can be cultured relatively easily and can be obtained not only from the bone marrow, but also from medical waste such as adipose…”
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CTGF in kidney fibrosis and glomerulonephritis by Toda, Naohiro, Mukoyama, Masashi, Yanagita, Motoko, Yokoi, Hideki

“…Glomerulonephritis, which causes inflammation in glomeruli, is a common cause of end-stage renal failure. Severe and prolonged inflammation can damage…”
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The impact of senescence-associated T cells on immunosenescence and age-related disorders by Fukushima, Yuji, Minato, Nagahiro, Hattori, Masakazu

“…Immunosenescence is age-associated changes in the immunological functions, including diminished acquired immunity against infection, pro-inflammatory traits,…”
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Bone regeneration in inflammation with aging and cell-based immunomodulatory therapy by Kushioka, Junichi, Chow, Simon Kwoon-Ho, Toya, Masakazu, Tsubosaka, Masanori, Shen, Huaishuang, Gao, Qi, Li, Xueping, Zhang, Ning, Goodman, Stuart B

“…Aging of the global population increases the incidence of osteoporosis and associated fragility fractures, significantly impacting patient quality of life and…”
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Emerging roles of inflammation-mediated endothelial-mesenchymal transition in health and disease by Yoshimatsu, Yasuhiro, Watabe, Tetsuro

“…Endothelial-mesenchymal transition (EndoMT), a cellular differentiation process in which endothelial cells (ECs) lose their properties and differentiate into…”
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PINK1-PARK2-mediated mitophagy in COPD and IPF pathogeneses by Tsubouchi, Kazuya, Araya, Jun, Kuwano, Kazuyoshi

“…Mitochondria regulate not only cell functions through energy generation but also aging-associated cell phenotypes. Impaired mitochondrial structural and…”
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Therapeutic potential of mesenchymal stem cells and their exosomes in severe novel coronavirus disease 2019 (COVID-19) cases by Tsuchiya, Atsunori, Takeuchi, Suguru, Iwasawa, Takahiro, Kumagai, Masaru, Sato, Takeki, Motegi, Satoko, Ishii, Yui, Koseki, Youhei, Tomiyoshi, Kei, Natsui, Kazuki, Takeda, Nobutaka, Yoshida, Yuki, Yamazaki, Fusako, Kojima, Yuichi, Watanabe, Yusuke, Kimura, Naruhiro

“…The novel coronavirus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of coronavirus disease 2019 (COVID-19) and the…”
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Neuroinflammation in Alzheimer's disease: microglial signature and their relevance to disease by Sobue, Akira, Komine, Okiru, Yamanaka, Koji

“…Alzheimer's disease (AD) is the most common form of dementia, pathologically characterized by senile plaques and neurofibrillary tangles (NFTs), resulting in…”
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The application of convolutional neural network to stem cell biology by Kusumoto, Dai, Yuasa, Shinsuke

“…Induced pluripotent stem cells (iPSC) are one the most prominent innovations of medical research in the last few decades. iPSCs can be easily generated from…”
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The etiopathogenesis of atopic dermatitis: barrier disruption, immunological derangement, and pruritus by Rerknimitr, Pawinee, Otsuka, Atsushi, Nakashima, Chisa, Kabashima, Kenji

“…Atopic dermatitis (AD) is a common chronic skin inflammatory disorder characterized by recurrent eczema accompanied by an intractable itch that leads to an…”
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