Search Results - "Infectious diseases and therapy"

Effect and Safety of Meropenem–Vaborbactam versus Best-Available Therapy in Patients with Carbapenem-Resistant Enterobacteriaceae Infections: The TANGO II Randomized Clinical Trial by Wunderink, Richard G., Giamarellos-Bourboulis, Evangelos J., Rahav, Galia, Mathers, Amy J., Bassetti, Matteo, Vazquez, Jose, Cornely, Oliver A., Solomkin, Joseph, Bhowmick, Tanaya, Bishara, Jihad, Daikos, George L., Felton, Tim, Furst, Maria Jose Lopez, Kwak, Eun Jeong, Menichetti, Francesco, Oren, Ilana, Alexander, Elizabeth L., Griffith, David, Lomovskaya, Olga, Loutit, Jeffery, Zhang, Shu, Dudley, Michael N., Kaye, Keith S.

“…Introduction Treatment options for carbapenem-resistant Enterobacteriaceae (CRE) infections are limited and CRE infections remain associated with high clinical…”
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In Vitro Bactericidal and Virucidal Efficacy of Povidone-Iodine Gargle/Mouthwash Against Respiratory and Oral Tract Pathogens by Eggers, Maren, Koburger-Janssen, Torsten, Eickmann, Markus, Zorn, Juergen

“…Introduction Recent virus epidemics and rising antibiotic resistance highlight the importance of hygiene measures to prevent and control outbreaks. We…”
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Sixty years of Amphotericin B: An Overview of the Main Antifungal Agent Used to Treat Invasive Fungal Infections by Cavassin, Francelise B., Baú-Carneiro, João Luiz, Vilas-Boas, Rogério R., Queiroz-Telles, Flávio

“…Introduced in the late 1950s, polyenes represent the oldest family of antifungal drugs. The discovery of amphotericin B and its therapeutic uses is considered…”
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Cefiderocol: A Novel Agent for the Management of Multidrug-Resistant Gram-Negative Organisms by Wu, Janet Y., Srinivas, Pavithra, Pogue, Jason M.

“…Cefiderocol, formerly S-649266, is a first in its class, an injectable siderophore cephalosporin that combines a catechol-type siderophore and cephalosporin…”
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Therapeutic Strategies for Emerging Multidrug-Resistant Pseudomonas aeruginosa by Kunz Coyne, Ashlan J., El Ghali, Amer, Holger, Dana, Rebold, Nicholas, Rybak, Michael J.

“…Multidrug-resistant (MDR) and extensively drug-resistant (XDR) Pseudomonas aeruginosa isolates are frequent causes of serious nosocomial infections that may…”
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Povidone-Iodine Demonstrates Rapid In Vitro Virucidal Activity Against SARS-CoV-2, The Virus Causing COVID-19 Disease by Anderson, Danielle E., Sivalingam, Velraj, Kang, Adrian Eng Zheng, Ananthanarayanan, Abhishek, Arumugam, Harsha, Jenkins, Timothy M., Hadjiat, Yacine, Eggers, Maren

“…Introduction As of 22 June 2020, Severe Acute Respiratory Syndrome (SARS)-coronavirus (CoV)-2 has infected more than 8.95 million people worldwide, causing >…”
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Vaccines for SARS-CoV-2: Lessons from Other Coronavirus Strains by Padron-Regalado, Eriko

“…The emergence of the strain of coronavirus SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) and its impact on global health have made imperative…”
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Continuous Evolution: Perspective on the Epidemiology of Carbapenemase Resistance Among Enterobacterales and Other Gram-Negative Bacteria by Hansen, Glen T.

“…The global emergence of carbapenemase-producing bacteria capable of hydrolyzing the once effective carbapenem antibiotics is considered a contemporary public…”
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Climate Change and Cascading Risks from Infectious Disease by Semenza, Jan C., Rocklöv, Joacim, Ebi, Kristie L.

“…Climate change is adversely affecting the burden of infectious disease throughout the world, which is a health security threat. Climate-sensitive infectious…”
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Infections in Cancer Patients with Solid Tumors: A Review by Rolston, Kenneth V. I.

“…Solid tumors are much more common than hematologic malignancies. Although severe and prolonged neutropenia is uncommon, several factors increase the risk of…”
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Infectious Disease Management and Control with Povidone Iodine by Eggers, Maren

“…With reports of vancomycin-resistant enterococci recently emerging in hospital settings, renewed focus is turning to the importance of multifaceted infection…”
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Etiology of Severe Community-Acquired Pneumonia in Adults Based on Metagenomic Next-Generation Sequencing: A Prospective Multicenter Study by Wu, Xiaodong, Li, Yuanyuan, Zhang, Ming, Li, Miaomiao, Zhang, Rong, Lu, Xin, Gao, Wei, Li, Qin, Xia, Yang, Pan, Pinhua, Li, Qiang

“…Background Metagenomic next-generation sequencing (mNGS) of bronchoalveolar lavage fluid (BALF) has the potential to improve the pathogen identification in…”
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Candida auris Candidemia in Critically Ill, Colonized Patients: Cumulative Incidence and Risk Factors by Briano, Federica, Magnasco, Laura, Sepulcri, Chiara, Dettori, Silvia, Dentone, Chiara, Mikulska, Malgorzata, Ball, Lorenzo, Vena, Antonio, Robba, Chiara, Patroniti, Nicolò, Brunetti, Iole, Gratarola, Angelo, D’Angelo, Raffaele, Di Pilato, Vincenzo, Coppo, Erika, Marchese, Anna, Pelosi, Paolo, Giacobbe, Daniele Roberto, Bassetti, Matteo

“…Introduction Candida auris ( C. auris ) is an emerging nosocomial pathogen, and a sharp rise in cases of colonization and infection has been registered in…”
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Coronavirus: Update Related to the Current Outbreak of COVID-19 by Gabutti, Giovanni, d’Anchera, Erica, Sandri, Federica, Savio, Marta, Stefanati, Armando

“…In December 2019, some cases of viral pneumonia were epidemiologically related to a new coronavirus in the province of Hubei, China. Subsequently, there has…”
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Coronavirus: Update Related to the Current Outbreak of COVID-19 by Gabutti, Giovanni, d'Anchera, Erica, Sandri, Federica, Savio, Marta, Stefanati, Armando

“…In December 2019, some cases of viral pneumonia were epidemiologically related to a new coronavirus in the province of Hubei, China. Subsequently, there has…”
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Defining the Epidemiology and Burden of Severe Respiratory Syncytial Virus Infection Among Infants and Children in Western Countries by Bont, Louis, Checchia, Paul A., Fauroux, Brigitte, Figueras-Aloy, Josep, Manzoni, Paolo, Paes, Bosco, Simões, Eric A. F., Carbonell-Estrany, Xavier

“…Introduction The REGAL (RSV [respiratory syncytial virus] Evidence—a Geographical Archive of the Literature) series provides a comprehensive review of the…”
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The Future of Respiratory Syncytial Virus Disease Prevention and Treatment by Domachowske, Joseph B., Anderson, Evan J., Goldstein, Mitchell

“…Respiratory syncytial virus (RSV) is a major cause of respiratory tract infections in infants, young children, and older or immunocompromised adults. Although…”
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Efficacy of Bamlanivimab/Etesevimab and Casirivimab/Imdevimab in Preventing Progression to Severe COVID-19 and Role of Variants of Concern by Falcone, Marco, Tiseo, Giusy, Valoriani, Beatrice, Barbieri, Chiara, Occhineri, Sara, Mazzetti, Paola, Vatteroni, Maria Linda, Suardi, Lorenzo Roberto, Riccardi, Niccolò, Pistello, Mauro, Tacconi, Danilo, Menichetti, Francesco

“…Introduction The aim of this study was to evaluate the risk of hospitalization or death in patients infected by SARS-CoV2 variants of concern (VOCs) receiving…”
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Ceftazidime-Avibactam for the Treatment of Serious Gram-Negative Infections with Limited Treatment Options: A Systematic Literature Review by Soriano, Alex, Carmeli, Yehuda, Omrani, Ali S., Moore, Luke S. P., Tawadrous, Margaret, Irani, Paurus

“…Introduction A systematic literature review was undertaken to evaluate real-world use of ceftazidime-avibactam for infections due to aerobic Gram-negative…”
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Metagenomic Next-Generation Sequencing for the Diagnosis of Pneumocystis jirovecii Pneumonia in Non-HIV-Infected Patients: A Retrospective Study by Jiang, Juan, Bai, Lu, Yang, Wei, Peng, Wenzhong, An, Jian, Wu, Yanhao, Pan, Pinhua, Li, Yuanyuan

“…Introduction This study aimed to evaluate the utility of metagenomic next-generation sequencing (mNGS) for the diagnosis of Pneumocystis jirovecii pneumonia…”
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