Search Results - "Ineu, Rafael Porto"

Green synthesis of silver nanoparticles using Ilex paraguariensis extracts: antimicrobial activity and acetilcolinesterase modulation in rat brain tissue by Vanin dos Santos Lima, Mirela, Beloni de Melo, Grasieli, Gracher Teixeira, Liandra, Grella Miranda, Cristiane, Hermes de Araújo, Pedro Henrique, Sayer, Claudia, Porto Ineu, Rafael, Leimann, Fernanda Vitória, Hess Gonçalves, Odinei

“…The silver nanoparticles (AgNPs) green synthesis has been investigated by selecting naturally occurred reduction and stabilizing/capping agents. In this work,…”
Get full text

Complex Methylmercury–Cysteine Alters Mercury Accumulation in Different Tissues of Mice by Roos, Daniel Henrique, Puntel, Robson Luiz, Lugokenski, Thiago Henrique, Ineu, Rafael Porto, Bohrer, Denise, Burger, Marilise E., Franco, Jeferson L., Farina, Marcelo, Aschner, Michael, Rocha, João Batista T., De Vargas Barbosa, Nilda B.

“…:  Methylmercury (MeHg) can cause deleterious effects in vertebrate tissues, particularly in the central nervous system. MeHg interacts with sulfhydryl groups…”
Get full text

Encapsulation of clove oil in nanostructured lipid carriers from natural waxes: Preparation, characterization and in vitro evaluation of the cholinesterase enzymes by de Meneses, Alessandra Cristina, Marques, Elisa Balbi Pinto, Leimann, Fernanda Vitória, Gonçalves, Odinei Hess, Ineu, Rafael Porto, de Araújo, Pedro Henrique Hermes, de Oliveira, Débora, Sayer, Claudia

“…[Display omitted] Eugenol is a phenolic compound largely found in the clove essential oil that possesses promising biological activity. However, its low water…”
Get full text

Influence of nanoencapsulated lutein on acetylcholinesterase activity: In vitro determination, kinetic parameters, and in silico docking simulations by Grella Miranda, Cristiane, dos Santos, Priscila Dayane Freitas, do Prado Silva, Jéssica Thaís, Vitória Leimann, Fernanda, Ferreira Borges, Bianca, Miguel Abreu, Rui, Porto Ineu, Rafael, Hess Gonçalves, Odinei

“…•Lutein was encapsulated using GRAS components yielding nanometric particles.•Encapsulated lutein acted as an acetylcholinesterase inhibitor.•In silico docking…”
Get full text

Quality of Natural Waters Surrounding Campo Mourão, State of Paraná, Southern Brazil: Water Resources Under the Influences from Urban and Agricultural Activities by Mendes, Sabrina Altmeyer, Gonçalves, Éderson Vecchietti, Frâncica, Letícia Scala, Correia, Leonardo Borges Coleto, Nicola, João Victor Nunes, Pestana, Ana Caroline Zago, da Silva Medeiros, Flávia Vieira, de Souza, Wyrllen Everson, Ineu, Rafael Porto, Peron, Ana Paula

“…The Campo and Km 119 rivers are sources of irrigation and water supply for the city of Campo Mourão, State of Paraná, Southern Brazil. However, these rivers…”
Get full text

Prospecting for Phytotoxicity and Enzymatic Modulation of Waters from Springs in the Surroundings of Campo Mourão, State of Paraná, Brazil, in Lactuca sativa L by Mendes, Sabrina Altmeyer, Frâncica, Letícia Scala, Gonçalves, Éderson Vecchietti, Coleto, Leonardo Borges, Nicola, João Victor Nunes, Pestana, Ana Caroline Zago, de Souza, Débora Cristina, Bueno, Paulo Agenor Alves, da Silva Medeiros, Flávia Vieira, Ineu, Rafael Porto, de Souza, Wyrllen Everson, Peron, Ana Paula

“…The Rio do Campo and Rio Km 119 rivers are under constant human pressure. Thus, it is necessary to assess the adverse effects caused by waters of these rivers…”
Get full text

Bioactivity screening of pinhão ( Araucaria Angustifolia (Bertol.) Kuntze) seed extracts: the inhibition of cholinesterases and α-amylases, and cytotoxic and anti-inflammatory activities by de Oliveira, Anielle, Moreira, Thaysa Fernandes Moya, Pepinelli, Ana Luisa Silva, Costa, Luis Gustavo Médice Arabel, Leal, Luana Eloísa, da Silva, Tamires Barlati Vieira, Gonçalves, Odinei Hess, Porto Ineu, Rafael, Dias, Maria Inês, Barros, Lillian, Abreu, Rui M V, Ferreira, Isabel C F R, Bracht, Lívia, Leimann, Fernanda Vitória

“…The objective of this work was to determine the potential bioactive properties of extracts from bio-residues of ( (Bertol.) Kuntze) seeds, namely the α-amylase…”
Get more information

Spermine reverses lipopolysaccharide-induced memory deficit in mice by Frühauf, Pâmella Karina Santana, Ineu, Rafael Porto, Tomazi, Lediane, Duarte, Thiago, Mello, Carlos Fernando, Rubin, Maribel Antonello

“…Lipopolysaccharide (LPS) induces neuroinflammation and memory deficit. Since polyamines improve memory in various cognitive tasks, we hypothesized that…”
Get full text

In vitro and in vivo evaluation of enzymatic and antioxidant activity, cytotoxicity and genotoxicity of curcumin-loaded solid dispersions by Silva de Sá, Igor, Peron, Ana Paula, Leimann, Fernanda Vitória, Bressan, Getúlio Nicola, Krum, Bárbara Nunes, Fachinetto, Roselei, Pinela, José, Calhelha, Ricardo Costa, Barreiro, Maria Filomena, Ferreira, Isabel C.F.R., Gonçalves, Odinei Hess, Ineu, Rafael Porto

“…Curcumin, the main bioactive polyphenolic compound in Curcuma longa L. rhizomes has a wide range of bioactive properties. Curcumin presents low solubility in…”
Get full text

Extraction of bioactive compounds from Curcuma longa L. using deep eutectic solvents: In vitro and in vivo biological activities by Oliveira, Grazielle, Marques, Caroline, de Oliveira, Anielle, de Almeida dos Santos, Amanda, do Amaral, Wanderlei, Ineu, Rafael Porto, Leimann, Fernanda Vitória, Peron, Ana Paula, Igarashi-Mafra, Luciana, Mafra, Marcos R.

“…In this work, deep eutectic solvents (DES-based menthol and cholinium chloride) and the ethanol, temperature, and times were selected to extract bioactive…”
Get full text

Chemometric evaluation of enzymatic hydrolysis in the production of fish protein hydrolysates with acetylcholinesterase inhibitory activity by Moreira, Thaysa Fernandes Moya, Pessoa, Luiz Gustavo Antunes, Seixas, Flavio Augusto Vicente, Ineu, Rafael Porto, Gonçalves, Odinei Hess, Leimann, Fernanda Vitória, Ribeiro, Ricardo Pereira

“…•Fish protein hydrolysates (FPH) were obtained from fish bioresidues.•Optimized enzymatic hydrolysis conditions were identified by chemometric approach.•FPH…”
Get full text

Selenothymidine protects against biochemical and behavioral alterations induced by ICV-STZ model of dementia in mice by Thomé, Gustavo Roberto, Oliveira, Vitor Antunes, Chitolina Schetinger, Maria Rosa, Saraiva, Rogério Aquino, Souza, Diego, Dorneles Rodrigues, Oscar Endrigo, Teixeira Rocha, João Batista, Ineu, Rafael Porto, Pereira, Maria Ester

“…The present study evaluated the neuroprotective effects of one selenium-containing AZT derivative compound (S1073) in memory and learning impairment caused by…”
Get full text

Evaluation of berberine nanoparticles as a strategy to modulate acetylcholinesterase activity by Leimann, Fernanda Vitória, de Souza, Luma Borges, de Oliveira, Byanca Pereira Moreira, Rossi, Bruna Franzon, da Silva, Patrícia Sabino, Shiraishi, Carlos Seiti Hurtado, Kaplum, Vanessa, Abreu, Rui Miguel, Pereira, Carla, Barros, Lillian, Peron, Ana Paula, Ineu, Rafael Porto, Oechsler, Bruno Francisco, Sayer, Claudia, de Araújo, Pedro Henrique Hermes, Gonçalves, Odinei Hess

“…[Display omitted] •Intense search for natural-based reversible inhibitors for cholinesterases.•Reversible action of berberine (pure and nanoparticles) on AChE…”
Get full text

Endogenous antioxidant properties of curcuminoids from Curcuma longa L. obtained by a single‐step extraction/nanoencapsulation approach by Santos, Priscila Dayane de Freitas, Coqueiro, Aline, Brum, Evelyne da Silva, Oliveira, Sara Marchesan, Leimann, Fernanda Vitória, Ineu, Rafael Porto, Bona, Evandro, Gonçalves, Odinei Hess

“…Curcuminoids found in turmeric have attracted attention due to their remarkable biological activity. Nanoencapsulation may improve their technological…”
Get full text

Antioxidant Activity of Encapsulated Extracts and Bioactives from Natural Sources by Gonçalves, Odinei H, Moreira, Thaysa F M, de Oliveira, Anielle, Bracht, Lívia, Ineu, Rafael P, Leimann, Fernanda V

“…The low water solubility and low bioavailability of natural bioactive substances such as polyphenols and flavonoids, either in pure form or extracts, are a…”
Get more information

Progesterone-loaded solid lipid nanoparticles for use in the regulation of the estrous cycle in female rats by Fogolari, Odinei, Leimann, Fernanda Vitória, Ineu, Rafael Porto, Rudy, Marcia, Ludwig, André Franco, Salles, Fernando Marques, de Arruda Amorim, João Paulo, Franci, Celso Rodrigues, Sagae, Sara Cristina, Sayer, Claudia, de Araújo, Pedro Henrique Hermes, Gonçalves, Odinei Hess

“…Protocols used for artificial insemination involve the effective synchronization of the estrous cycle by the administration of exogenous hormones including…”
Get full text

Antioxidant effect of zinc chloride against ethanol-induced gastrointestinal lesions in rats by Ineu, Rafael Porto, Oliveira, Cláudia Sirlene, Oliveira, Vitor Antunes, Moraes-Silva, Lucélia, da Luz, Sônia Cristina Almeida, Pereira, Maria Ester

“…•Ethanol consistently induced damage in the rat glandular stomach and intestine.•Zinc content in stomach was raised by treatment with ZnCl2.•Renal and hepatic…”
Get full text

Lactating and non-lactating rats differ in sensitivity to HgCl2: Protective effect of ZnCl2 by Oliveira, Vitor Antunes, Oliveira, Cláudia Sirlene, Ineu, Rafael Porto, Moraes-Silva, Lucélia, de Siqueira, Lucieli Flores, Pereira, Maria Ester

“…This work investigated zinc (Zn) and mercury (Hg) effects on oxidative parameters, markers of toxicity and metal levels in different tissues from non-lactating…”
Get full text

Nanoencapsulation of lutein and its effect on mice's declarative memory by do Prado Silva, Jéssica Thaís, Geiss, Júlia Maria Tonin, Oliveira, Sara Marchesan, Brum, Evelyne da Silva, Sagae, Sara Cristina, Becker, Daniela, Leimann, Fernanda Vitória, Ineu, Rafael Porto, Guerra, Gustavo Petri, Gonçalves, Odinei Hess

“…Lutein is a xanthophyll carotenoid widely known by its biological properties and low toxicity. When located in the brain, lutein may inhibit damage mechanisms,…”
Get full text

Lactating and non-lactating rats differ in sensitivity to HgCl(2): Protective effect of ZnCl(2) by Oliveira, Vitor Antunes, Oliveira, Cláudia Sirlene, Ineu, Rafael Porto, Moraes-Silva, Lucélia, de Siqueira, Lucieli Flores, Pereira, Maria Ester

“…This work investigated zinc (Zn) and mercury (Hg) effects on oxidative parameters, markers of toxicity and metal levels in different tissues from non-lactating…”
Get full text