Search Results - "Indrová, M"

Immunotherapy augments the effect of 5-azacytidine on HPV16-associated tumours with different MHC class I-expression status by SIMOVA, J, POLLAKOVA, V, INDROVA, M, MIKYSKOVA, R, BIEBLOVA, J, STEPANEK, I, BUBENIK, J, REINIS, M

“…Background: Epigenetic mechanisms have important roles in the tumour escape from immune responses, such as in MHC class I downregulation or altered expression…”
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Loss of tumorigenicity of murine colon carcinoma MC38/0 cell line after transduction with a retroviral vector carrying murine IL-12 genes by Pajtasz-Piasecka, E, Szyda, A, Rossowska, J, Krawczenko, A, Indrová, M, Grabarczyk, P, Wysocki, P, Mackiewicz, A, Duś, D

“…Cells of transplantable MC38 colon carcinoma of C57BL/6 mice were adapted to growth in vitro as the MC38/0 cell line. Along the establishing process, MC38/0…”
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Therapy of HPV 16-associated carcinoma with dendritic cell-based vaccines: in vitro priming of the effector cell responses by DC pulsed with tumour lysates and synthetic RAHYNIVTF peptide by Indrová, M, Bubeník, J, Símová, J, Vonka, V, Nemecková, S, Mendoza, L, Reinis, M

“…Murine carcinoma induced by MK 16 cells expressing HPV 16 E6/E7 oncogenes was utilized to examine the therapeutic effect of dendritic cell-based tumour…”
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Immunotherapeutic efficacy of vaccines generated by fusion of dendritic cells and HPV16-associated tumour cells by Simova, J, Bubenik, J, Bieblova, J, Indrova, M, Jandlova, T

“…Utilization of vaccines generated by fusion of dendritic cells and tumour cells is a promising approach to tumour immunotherapy. We have examined the…”
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Immunogenicity of dendritic cell-based HPV16 E6/E7 peptide vaccines: CTL activation and protective effects by Indrová, M, Reinis, M, Bubeník, J, Jandlová, T, Bieblová, J, Vonka, V, Velek, J

“…We have investigated the capacity of cellular vaccines based on dendritic cells loaded with human HPV16 E6/E7 oncoprotein-derived peptides to induce immune…”
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Local IFN-gamma therapy of HPV16-associated tumours by Mikysková, R, Bieblová, J, Símová, J, Indrová, M, Jandlová, T, Vonka, V, Smahel, M, Bubeník, J, Mendoza, L

“…We have examined whether peritumoral administration of IFN-gamma can inhibit growth of HPV16-associated, MHC class I- tumour MK16/1/IIIABC (MK16) transplanted…”
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Chemoimmunotherapy of cancer: potentiated effectiveness of granulocyte-macrophage colony-stimulating factor and ifosfamide derivative CBM-4A by Indrová, M, Bubeník, J, Símová, J, Bieblová, J, Jandlová, T, Smahel, M, Vonka, V, Glazman-Kusnierczyk, H, Pajtasz-Piasecka, E, Radzikowski, C, Mikysková, R

“…The effectiveness of combined chemoimmunotherapy with ifosfamide derivative CBM-4A and granulocyte-macrophage colony-stimulating factor (GM-CSF) was…”
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Use of cryopreserved lymphocytes for assessment of the immunological effects of interferon therapy in renal cell carcinoma patients by Sobota, Vesna, Bubenı́k, Jan, Indrová, Marie, Vlk, Vladimı́r, Jakoubková, Jaroslava

“…Experiments were designed to assess whether cryopreserved PBL could be used to monitor the immunological effects of IFN-α therapy in renal cell carcinoma (RCC)…”
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Freezing and thawing of murine bone marrow-derived dendritic cells does not alter their immunophenotype and antigen presentation characteristics by Mendoza, L, Bubeník, J, Indrová, M, Bieblová, J, Vonka, V, Símová, J

“…The aim of this paper was to assess whether the BMDC after freezing and thawing are capable to retain the immunophenotype and antigen-presenting capacity. BMDC…”
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Peritumoral administration of antigen-unstimulated bone marrow-derived dendritic cells inhibits tumour growth by Mendoza, L, Indrová, M, Hájková, R, Reinis, M, Smahel, M, Vonka, V, Bubeník, J, Jandlová, T

“…Murine BM cells from B6 mice were grown in vitro in medium supplemented with GM-CSF and IL-4 to differentiate DC from DC precursors. After 10 days of culture,…”
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Irradiated IL-2 gene-modified plasmacytoma vaccines are more efficient than live vaccines by Símová, J, Bubeník, J, Jandlová, T, Indrová, M

“…The effect of irradiation on the therapeutic efficacy of IL-2 gene-modified plasmacytoma cells used as a vaccine in the immunotherapy of parental murine…”
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Adjuvant cytokine treatment of minimal residual disease after surgical therapy in mice carrying HPV16-associated tumours: cytolytic activity of spleen cells from tumour regressors by Indrová, M, Mikysková, R, Jandlová, T, Vonka, V, Bubeník, J, Bieblová, J

“…It has been found previously that IL-2, IFNgamma and GM-CSF were capable of reducing the recurrence rate of HPV 16-associated tumours in mice with SMRTD. We…”
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Tumour-inhibitory effects of dendritic cells administered at the site of HPV 16-induced neoplasms by Mendoza, L, Bubeník, J, Símová, J, Korb, J, Bieblová, J, Vonka, V, Indrová, M, Mikysková, R, Jandlová, T

“…Experiments were designed to examine whether administration of APC at the site of HPV 16-associated tumours can inhibit tumour growth and whether the efficacy…”
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CD80 and IL-2 signals cooperate in the regression of tumors transplanted in congenitally athymic mice by Sobota, V, Indrová, M, Rössner, P, Bubeník, J, Jandlová, T

“…Interleukin-2 and CD80 transfectants of a methylcholanthrene-induced murine sarcoma Mc12 (Mc12-IL-2 and Mc12-CD80 cells) with similar tumorigenicity in…”
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Bone marrow dendritic cell-based anticancer vaccines by Indrová, M, Mendoza, L, Reinis, M, Vonka, V, Smahel, M, Nĕmecková, S, Jandlová, T, Bubeník, J

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Interleukin 2 gene therapy of surgical minimal residual tumour disease: characterization of cytolytic effector cells from tumour progressors and regressors by Hájková, R, Indrová, M, Jandlová, T, Bubeník, J, Reinis, M

“…Experiments were designed to characterize cytolytic effector cells from mice with SMRTD treated with IL-2 gene therapy. Mice were inoculated with syngeneic…”
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IL-2 gene-modified tumour vaccines: monitoring of IL-2 levels in serum and peritoneal cavity of vaccinated mice by Indrová, M, Pajtasz-Piasecka, E, Jandlová, T, Símová, J, Bubeník, J, Radzikowski, C

“…IL-2 kinetics was assessed in mice vaccinated with irradiated syngeneic tumour vaccines carrying an inserted IL-2 gene and producing constitutively IL-2. For…”
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Effects of 5-azacytidine and trichostatin A on dendritic cell maturation by Stepanek, I, Indrova, M, Bieblova, J, Fucikova, J, Spisek, R, Bubenik, J, Reinis, M

“…Maturation of dendritic cells (DC) towards functional antigen-presenting cells is a complex process, the regulation of which may also involve epigenetic…”
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Cross-reactivity of murine and hamster IL-2 mitogenic signal by Sobotková, E., Indrová, M., Šímová, J., Bubeník, J., Vonka, V.

“…In an effort to develop a model system for studying immune reactions against human papillomavirus (HPV)-transformed cells we have recently transformed Syrian…”
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Granulocyte-macrophage colony-stimulating factor-producing tumour vaccines by Rössner, P, Bubeník, J, Sobota, V, Indrová, M, Hájková, R, Mendoza, L, Jandlová, T, Símová, J

“…Murine sarcoma MC12 cells were transfected with the gene coding for murine granulocyte-macrophage colony-stimulating factor (GM-CSF). Tumorigenicity of a…”
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