Search Results - "Indolfi, Laura"

The role of scaffold microarchitecture in engineering endothelial cell immunomodulation by Indolfi, Laura, Baker, Aaron B, Edelman, Elazer R

“…Abstract The implantation of matrix-embedded endothelial cells (MEECs) has been reported to have great therapeutic potential in controlling the vascular…”
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Heparanase Regulates Thrombosis in Vascular Injury and Stent-Induced Flow Disturbance by Baker, Aaron B., PhD, Gibson, William J., BS, Kolachalama, Vijaya B., PhD, Golomb, Mordechai, MD, Indolfi, Laura, PhD, Spruell, Christopher, Zcharia, Eyal, PhD, Vlodavsky, Israel, PhD, Edelman, Elazer R., MD, PhD

“…Objectives The purpose of this study was to examine the role of heparanase in controlling thrombosis following vascular injury or endovascular stenting…”
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Coating process and early stage adhesion evaluation of poly(2-hydroxy-ethyl-methacrylate) hydrogel coating of 316L steel surface for stent applications by Indolfi, Laura, Causa, Filippo, Netti, Paolo Antonio

“…In this study, a spray-coating method has been set up with the aim to control the coating of poly(2-hydroxy-ethyl-methacrylate) (pHEMA), an hydrophilic…”
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Microsphere-integrated drug-eluting stents: PLGA microsphere integration in hydrogel coating for local and prolonged delivery of hydrophilic antirestenosis agents by Indolfi, Laura, Causa, Filippo, Giovino, Concetta, Ungaro, Francesca, Quaglia, Fabiana, Netti, Paolo Antonio

“…The development of a novel generation of drug‐eluting stent (DES) relies upon the idea to obtain very flexible platforms able to overcome some issues…”
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Tubular bridges for bronchial epithelial cell migration and communication by Zani, Brett G, Indolfi, Laura, Edelman, Elazer R

“…Biological processes from embryogenesis to tumorigenesis rely on the coordinated coalescence of cells and synchronized cell-to-cell communication…”
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Bioactivated collagen-based scaffolds embedding protein-releasing biodegradable microspheres: tuning of protein release kinetics by Biondi, Marco, Indolfi, Laura, Ungaro, Francesca, Quaglia, Fabiana, La Rotonda, Maria Immacolata, Netti, Paolo A.

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Phase I study of PTM-101 as neoadjuvant therapy for borderline resectable or locally advanced pancreatic ductal adenocarcinoma: A trial in progress by Pilgrim, Charles, Smith, Marty, Ban, Jun, Ellis, Sam, Zalcberg, John Raymond, Markman, Ben, Lashof-Sullivan, Margaret, Indolfi, Laura

“…TPS775 Background: While there have been tremendous advances in cancer treatment, critical challenges remain including limited ability of drugs to successfully…”
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Novel targeted and sustained drug delivery therapy for localized pancreatic cancer: Validation in porcine models and minimally invasive surgical feasibility in human cadavers by Lashof-Sullivan, Margaret, Kim, Michael Paul, Tzeng, Ching-Wei David, Indolfi, Laura

“…Abstract only e16747 Background: As systemic therapy improves, control of localized pancreatic adenocarcinoma (PDAC) remains a major challenge. Up to 40% of…”
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Abstract B26: Targeted and sustained drug delivery therapy for localized pancreatic cancer: In vivo validation in porcine models by Lashof-Sullivan, Margaret, McSweeney, Amanda L., Ting, David T., Kim, Michael P., Tzeng, Ching-Wei D., Indolfi, Laura

“…Abstract As systemic therapy improves, local control of nonmetastatic pancreatic adenocarcinoma (PDAC) remains a major challenge. Up to 40% of patients present…”
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Abstract 2393: Development of a novel implantable drug-eluting product for the local treatment of pancreatic adenocarcinoma by Lashof-Sullivan, Margaret, Sloan, Leslie S., Kim, Michael P., Indolfi, Laura, Tzeng, Ching-Wei D.

“…Abstract Background Local control of non-metastatic pancreatic ductal adenocarcinoma (PDAC) remains a major challenge. Therapies with reduced systemic toxicity…”
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Abstract CT106: First-in-human phase 1 study of paclitaxel-eluting PTM-101 film in subjects with borderline resectable or locally advanced pancreatic cancers by Pilgrim, Charles, Smith, Marty, Ban, Ee-Jun, Ellis, Samantha, Zalcberg, John, Markman, Benjamin, Lashof-Sullivan, Margaret, Indolfi, Laura

“…Abstract Background Unlike many other types of cancer, improvements in the treatment of pancreatic cancer have been very limited, in part due to the inability…”
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A tunable delivery platform to provide local chemotherapy for pancreatic ductal adenocarcinoma by Indolfi, Laura, Ligorio, Matteo, Ting, David T, Xega, Kristina, Tzafriri, Abraham R, Bersani, Francesca, Aceto, Nicola, Thapar, Vishal, Fuchs, Bryan C, Deshpande, Vikram, Baker, Aaron B, Ferrone, Cristina R, Haber, Daniel A, Langer, Robert, Clark, Jeffrey W, Edelman, Elazer R

“…Abstract Pancreatic ductal adenocarcinoma (PDAC) is one of the most devastating and painful cancers. It is often highly resistant to therapy owing to inherent…”
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Microsphere-integrated collagen scaffolds for tissue engineering: Effect of microsphere formulation and scaffold properties on protein release kinetics by Ungaro, Francesca, Biondi, Marco, d'Angelo, Ivana, Indolfi, Laura, Quaglia, Fabiana, Netti, Paolo Antonio, La Rotonda, Maria Immacolata

“…A promising approach to control the time and space distribution of signalling molecules inside tissue engineering scaffolds consists in entrapping…”
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Abstract 4584: A novel drug-eluting platform for localized treatment of pancreatic cancer by Ligorio, Matteo, Indolfi, Laura, Ting, David T., Xega, Kristina, Aceto, Nicola, Bersani, Francesca, Ferrone, Cristina R., Haber, Daniel A., Langer, Robert, Edelman, Elazer R., Clark, Jeffrey W.

“…Abstract INTRODUCTION. The majority of patients with pancreatic ductal adenocarcinoma (PDAC) succumb to the disease within 12-24 months from their diagnosis…”
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Abstract 75: Heparanase Mediates Arteriothrombosis Following Vascular Injury or Endovascular Stenting by Baker, Aaron, Gibson, William, Kolachalama, Vijaya, Golomb, Mordechai, Indolfi, Laura, Spruell, Christopher, Zcharia, Eyal, Vlodavsky, Israel, Edelman, Elazer

“…Abstract only Background: Heparanase cleaves heparan sulfate proteoglycans (HSPGs), key components of the extracellular matrix and critical endothelial…”
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Bioactivated collagen-based scaffolds embedding protein-releasing biodegradable microspheres: tuning of protein release kinetics by Biondi, Marco, Indolfi, Laura, Ungaro, Francesca, Quaglia, Fabiana, La Rotonda, Maria Immacolata, Netti, Paolo A.

“…In tissue engineering, the recapitulation of natural sequences of signaling molecules, such as growth factors, as occurring in the native extracellular matrix…”
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Abstract 5481: Heparanase Regulates the Thrombotic Potential of Vascular Injury and Stent Placement by Baker, Aaron, Gibson, William, Kolachalama, Vijaya B, Golumb, Mordachai, Indolfi, Laura, Edelman, Elazer R

“…Abstract only Background: Heparanase cleaves heparan sulfate proteoglycans (HSPGs), key components of the extracellular matrix and critical endothelial…”
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Matrix-embedded endothelial cells are protected from the uremic milieu by Chitalia, Vipul C., Murikipudi, Sylaja, Indolfi, Laura, Rabadi, Laith, Valdez, Rachel, Franses, Joseph W., Edelman, Elazer R.

“…Background. Endothelial cells (ECs) embedded in 3D matrices [matrix-embedded endothelial cells (MEECs)] of denatured collagen implanted around vascular access…”
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