Search Results - "Inderbinen, Silvia G"

11β-Hydroxysteroid dehydrogenases control access of 7β,27-dihydroxycholesterol to retinoid-related orphan receptor γ[S] by Beck, Katharina R., Inderbinen, Silvia G., Kanagaratnam, Sharavan, Kratschmar, Denise V., Jetten, Anton M., Yamaguchi, Hideaki, Odermatt, Alex

“…Oxysterols previously were considered intermediates of bile acid and steroid hormone biosynthetic pathways. However, recent research has emphasized the roles…”
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Finding New Molecular Targets of Familiar Natural Products Using In Silico Target Prediction by Mayr, Fabian, Möller, Gabriele, Garscha, Ulrike, Fischer, Jana, Rodríguez Castaño, Patricia, Inderbinen, Silvia G, Temml, Veronika, Waltenberger, Birgit, Schwaiger, Stefan, Hartmann, Rolf W, Gege, Christian, Martens, Stefan, Odermatt, Alex, Pandey, Amit V, Werz, Oliver, Adamski, Jerzy, Stuppner, Hermann, Schuster, Daniela

“…Natural products comprise a rich reservoir for innovative drug leads and are a constant source of bioactive compounds. To find pharmacological targets for new…”
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Species-specific differences in the inhibition of 11β-hydroxysteroid dehydrogenase 2 by itraconazole and posaconazole by Inderbinen, Silvia G., Zogg, Michael, Kley, Manuel, Smieško, Martin, Odermatt, Alex

“…11β-hydroxysteroid dehydrogenase 2 (11β-HSD2) converts active 11β-hydroxyglucocorticoids to their inactive 11-keto forms, thereby preventing inappropriate…”
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Activation of retinoic acid-related orphan receptor γ(t) by parabens and benzophenone UV-filters by Inderbinen, Silvia G., Kley, Manuel, Zogg, Michael, Sellner, Manuel, Fischer, André, Kędzierski, Jacek, Boudon, Stéphanie, Jetten, Anton M., Smieško, Martin, Odermatt, Alex

“…Retinoic acid-related orphan receptor γt (RORγt) regulates immune responses and its impaired function contributes to inflammatory and autoimmune diseases and…”
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Tributyltin and triphenyltin induce 11β-hydroxysteroid dehydrogenase 2 expression and activity through activation of retinoid X receptor α by Inderbinen, Silvia G., Engeli, Roger T., Rohrer, Simona R., Di Renzo, Erminio, Aengenheister, Leonie, Buerki-Thurnherr, Tina, Odermatt, Alex

“…[Display omitted] •TBT and TPT induce the transcription of 11β-HSD2 in JEG-3 cells.•Upregulation of 11β-HSD2 results in reduced cortisol-dependent activation…”
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