Search Results - "Inda, Márcia A."

Estrogen Receptor Pathway Activity Score to Predict Clinical Response or Resistance to Neoadjuvant Endocrine Therapy in Primary Breast Cancer by Inda, Márcia A, Blok, Erik J, Kuppen, Peter J K, Charehbili, Ayoub, den Biezen-Timmermans, Eveline C, van Brussel, Anne, Fruytier, Sevgi E, Meershoek-Klein Kranenbarg, Elma, Kloet, Susan, van der Burg, Bart, Martens, John W M, Sims, Andrew H, Turnbull, Arran K, Dixon, J Michael, Verhaegh, Wim, Kroep, Judith R, van de Velde, Cornelis J H, van de Stolpe, Anja

“…Endocrine therapy is important for management of patients with estrogen receptor (ER)-positive breast cancer; however, positive ER staining does not reliably…”
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Impact of hormonal biomarkers on response to hormonal therapy in advanced and recurrent endometrial cancer by van Weelden, Willem Jan, Lalisang, Roy I., Bulten, Johan, Lindemann, Kristina, van Beekhuizen, Heleen J., Trum, Hans, Boll, Dorry, Werner, Henrica M.J., van Lonkhuijzen, Luc R.C.W., Yigit, Refika, Forsse, David, Witteveen, Petronella O., Galaal, Khadra, van Ginkel, Alexandra, Bignotti, Eliana, Weinberger, Vit, Sweegers, Sanne, Kroep, Judith R., Cabrera, Silvia, Snijders, Marc P.L.M., Inda, Márcia A., Eriksson, Ane Gerda Z., Krakstad, Camilla, Romano, Andrea, van de Stolpe, Anja, Pijnenborg, Johanna M.A.

“…Approximately 20% of women with endometrial cancer have advanced-stage disease or suffer from a recurrence. For these women, prognosis is poor, and palliative…”
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Oestrogen receptor pathway activity is associated with outcome in endometrial cancer by van Weelden, Willem Jan, van der Putten, Louis J. M., Inda, Márcia A., van Brussel, Anne, Snijders, Marc P. L. M., Schriever, Lisanne M. M., Bulten, Johan, Massuger, Leon F. A. G., van de Stolpe, Anja, Pijnenborg, Johanna M. A.

“…Background Oestrogen receptor (ER) expression is a prognostic biomarker in endometrial cancer (EC). However, expression does not provide information about the…”
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Selection of Personalized Patient Therapy through the Use of Knowledge-Based Computational Models That Identify Tumor-Driving Signal Transduction Pathways by VERHAEGH, Wim, VAN OOIJEN, Henk, VAN DE STOLPE, Anja, INDA, Márcia A, HATZIS, Pantelis, VERSTEEG, Rogier, SMID, Marcel, MARTENS, John, FOEKENS, John, VAN DE WIEL, Paul, CLEVERS, Hans

“…Increasing knowledge about signal transduction pathways as drivers of cancer growth has elicited the development of "targeted drugs," which inhibit aberrant…”
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ER and PI3K Pathway Activity in Primary ER Positive Breast Cancer Is Associated with Progression-Free Survival of Metastatic Patients under First-Line Tamoxifen by Sieuwerts, Anieta M, Inda, Márcia A, Smid, Marcel, van Ooijen, Henk, van de Stolpe, Anja, Martens, John W M, Verhaegh, Wim F J

“…Estrogen receptor positive (ER+) breast cancer patients are eligible for hormonal treatment, but only around half respond. A test with higher specificity for…”
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SigWinR; the SigWin-detector updated and ported to R by de Leeuw, Wim C, Rauwerda, Han, Inda, Márcia A, Bruning, Oskar, Breit, Timo M

“…Our SigWin-detector discovers significantly enriched windows of (genomic) elements in any sequence of values (genes or other genomic elements in a DNA…”
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Heterogeneity in Signaling Pathway Activity within Primary and between Primary and Metastatic Breast Cancer by Inda, Márcia A, van Swinderen, Paul, van Brussel, Anne, Moelans, Cathy B, Verhaegh, Wim, van Zon, Hans, den Biezen, Eveline, Bikker, Jan Willem, van Diest, Paul J, van de Stolpe, Anja

“…Targeted therapy aims to block tumor-driving signaling pathways and is generally based on analysis of one primary tumor (PT) biopsy. Tumor heterogeneity within…”
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SigWin-detector: a Grid-enabled workflow for discovering enriched windows of genomic features related to DNA sequences by Inda, Márcia A, van Batenburg, Marinus F, Roos, Marco, Belloum, Adam S Z, Vasunin, Dmitry, Wibisono, Adianto, van Kampen, Antoine H C, Breit, Timo M

“…Chromosome location is often used as a scaffold to organize genomic information in both the living cell and molecular biological research. Thus,…”
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Collaborative e-Science Experiments and Scientific Workflows by Belloum, A., Inda, M. A., Vasunin, D., Korkhov, V., Zhiming Zhao, Rauwerda, H., Breit, T. M., Bubak, M., Hertzberger, L. O.

“…Recent advances in Internet and grid technologies have greatly enhanced scientific experiments' life cycle. In addition to compute- and data-intensive tasks,…”
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Abstract 2656: Estrogen receptor pathway activity in endometrial carcinomas and its relation to tumor grade and recurrence by Putten, Louis J. van der, Brussel, Anne van, Weelden, Willem Jan van, Inda, Márcia A. de, Massuger, Leon F., Ooijen, Henk van, Stolpe, Anja van de, Pijnenborg, Johanna M.

“…Abstract Background Immunohistochemical (IHC) loss of expression of the estrogen (ER) and progesterone receptor (PR) from endometrial carcinomas is associated…”
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Abstract 5291: Prognosis within different breast cancer subtypes using functional activity of signaling pathways by van Ooijen, Henk, Inda, Márcia A., Hoffmann, Ralf, van de Wiel, Paul, van de Stolpe, Anja, Verhaegh, Wim

“…Abstract Introduction Gene signatures to assess prognosis of breast cancer patients are generally restricted to ER-positive/luminal breast cancers, and provide…”
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Abstract 3938: Predicting first line tamoxifen response of recurrent ER+ breast cancer patients based on transcriptional activity of signaling pathways by Sieuwerts, Anieta M., Smid, Marcel, Inda, Márcia A., Foekens, John A., van de Stolpe, Anja, Martens, John W.M., Verhaegh, Wim F.J.

“…Abstract Introduction Generally, estrogen receptor positive (ER+) breast cancer patients are eligible for hormonal treatment, but roughly half of them respond,…”
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Multiple Histogram Method and Static Monte Carlo Sampling by Inda, Márcia A., Frenkel, Daan

“…We describe an approach to use multiple‐histogram methods in combination with static, biased Monte Carlo simulations. To illustrate this, we computed the…”
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Cover Picture: Macromol. Theory Simul. 1/2004 by Inda, Márcia A., Frenkel, Daan

“…Cover: Histograms of the x ‐coordinate of the end‐to‐end vector of an athermal polymer subject to an external force. Above: raw data – Rosenbluth sampling…”
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Abstract 3690: Measuring functional signal transduction pathway activity on breast cancer tissue samples to determine intra-tumor heterogeneity and heterogeneity between primary and metastatic tumors by Stolpe, Anja Van De, Brussel, Anne van, Moelans, Cathy, Inda, Marcia A., Verhaegh, Wim, Biezen, Eveline den, Diest, Paul van

“…Abstract Background Treatment with targeted drugs is increasingly used in breast cancer aiming to block the tumor driving pathway(s). Drug choice is often…”
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A simple and efficient parallel FFT algorithm using the BSP model by Inda, Márcia A., Bisseling, Rob H.

“…We present a new parallel radix-4 FFT algorithm based on the BSP model. Our parallel algorithm uses the group-cyclic distribution family, which makes it simple…”
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Interactive Workflows in a Virtual Laboratory for e-Bioscience: The SigWin-Detector Tool for Gene Expression Analysis by Inda, Marcia A., Belloum, Adam S.Z., Roos, Marco, Vasunin, Dmitry, Laat, Cees De, Hertzberger, L.O., Breit, Timo M.

“…Explorative research is a vital part of biological sciences. Biologists frequently have to examine and compare multiple (large) sets of biological data in an…”
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Network formation as a cluster-cluster diffusion-limited aggregation process, 2. Modelling the polyethylene crosslinking process using Monte Carlo and graph techniques by Samios, Dimitrios, Schifino, José, Inda, Márcia A., Thompson, Mark

“…A Monte Carlo simulation of the network formation of polyethylene radicals has been carried out using the reaction modelling scheme and a graph exploration…”
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