Search Results - "Inceler, Nazan"
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Synthesis, biological evaluation and molecular docking studies of trans-indole-3-acrylamide derivatives, a new class of tubulin polymerization inhibitors
Published in Bioorganic & medicinal chemistry (15-06-2014)“…[Display omitted] In this study, we synthesized a series of trans-indole-3-acrylamide derivatives (3a–k) and investigated their activity for inhibition of cell…”
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Synthesis of ester and amide derivatives of 1-phenyl-3-(thiophen-3-yl)-1H-pyrazole-4-carboxylic acid and study of their anticancer activity
Published in Medicinal chemistry research (01-07-2013)“…A series of novel thiophene containing 1,3-diarylpyrazole derivatives were synthesized and the structures were determined by IR, 1 H-NMR, and HRMS analysis…”
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Synthesis, cytotoxicity, and molecular properties prediction of novel 1,3-diarylpyrazole derivatives
Published in Medicinal chemistry research (01-10-2013)“…A novel combinatorial library of ester and amide derivatives of 1,3-diarylpyrazoles was designed and synthesized. Anticancer activities of these compounds were…”
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Design, synthesis and biological evaluation of novel 1,3-diarylpyrazoles as cyclooxygenase inhibitors, antiplatelet and anticancer agents
Published in MedChemComm (01-05-2018)“…With the aim of achieving new compounds possessing both anti-inflammatory and antiplatelet activities, we synthesized (…”
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Design, synthesis and biological evaluation of novel 1,3-diarylpyrazoles as cyclooxygenase inhibitors, antiplatelet and anticancer agentsElectronic supplementary information (ESI) available. See DOI: 10.1039/c8md00022k
Published 25-05-2018“…With the aim of achieving new compounds possessing both anti-inflammatory and antiplatelet activities, we synthesized ( E…”
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Design, synthesis and biological evaluation of novel 1,3-diarylpyrazoles as cyclooxygenase inhibitors, antiplatelet and anticancer agents† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c8md00022k
Published in MedChemComm (06-04-2018)“…( E )-3-[3-(Pyridin-3/4-yl)-1-(phenyl/sulfonylmethylphenyl)-1 H -pyrazol-4-yl]acrylamides were synthesized and their COX-1 and COX-2 inhibitory, antiplatelet…”
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Analgesic and Anti‐Inflammatory Effect of Pyridazinones/Aminoantipyrine Hybrids
Published in The FASEB journal (01-04-2011)“…In this study we have investigated the analgesic and anti‐inflammatory effect of synthesized 6‐subsititue‐3(2H)‐pyridazinone/aminoantipyrine hybrids. Twelve…”
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Novel 1,3-diarylpyrazole acrylamides: synthesis, antiplatelet activity screening, and in silico evaluation studies
Published in Medicinal chemistry research (01-12-2013)“…( E )-3-[3-(pyridin-4-yl)-1-phenyl-1 H -pyrazole-4-yl]acryl amides were evaluated for their antiplatelet activities. Compounds 4o and 4r were found as active…”
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Synthesis of antipyrine/pyridazinone hybrids and investigation of their in vivo analgesic and anti-inflammatory activities
Published in Turkish journal of chemistry (01-01-2012)Get full text
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