Search Results - "Incardona, John"

Molecular Mechanisms of Crude Oil Developmental Toxicity in Fish by Incardona, John P.

“…With major oil spills in Korea, the United States, and China in the past decade, there has been a dramatic increase in the number of studies characterizing the…”
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The influence of heart developmental anatomy on cardiotoxicity-based adverse outcome pathways in fish by Incardona, John P., Scholz, Nathaniel L.

“…The developing fish heart is vulnerable to a diverse array of toxic chemical contaminants in freshwater, estuarine, and marine habitats. Globally occurring…”
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Crude Oil Impairs Cardiac Excitation-Contraction Coupling in Fish by Brette, Fabien, Machado, Ben, Cros, Caroline, Incardona, John P., Scholz, Nathaniel L., Block, Barbara A.

“…Crude oil is known to disrupt cardiac function in fish embryos. Large oil spills, such as the Deepwater Horizon (DWH) disaster that occurred in 2010 in the…”
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Oil droplet fouling and differential toxicokinetics of polycyclic aromatic hydrocarbons in embryos of Atlantic haddock and cod by Sørensen, Lisbet, Sørhus, Elin, Nordtug, Trond, Incardona, John P, Linbo, Tiffany L, Giovanetti, Laura, Karlsen, Ørjan, Meier, Sonnich

“…The impact of crude oil pollution on early life stages (ELS) of fish, including larvae and embryos, has received considerable attention in recent years. Of the…”
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Cardiac toxicity of 5-ring polycyclic aromatic hydrocarbons is differentially dependent on the aryl hydrocarbon receptor 2 isoform during zebrafish development by Incardona, John P., Linbo, Tiffany L., Scholz, Nathaniel L.

“…Petroleum-derived compounds, including polycyclic aromatic hydrocarbons (PAHs), commonly occur as complex mixtures in the environment. Recent studies using the…”
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Deepwater Horizon crude oil impacts the developing hearts of large predatory pelagic fish by Incardona, John P, Gardner, Luke D, Linbo, Tiffany L, Brown, Tanya L, Esbaugh, Andrew J, Mager, Edward M, Stieglitz, John D, French, Barbara L, Labenia, Jana S, Laetz, Cathy A, Tagal, Mark, Sloan, Catherine A, Elizur, Abigail, Benetti, Daniel D, Grosell, Martin, Block, Barbara A, Scholz, Nathaniel L

“…The Deepwater Horizon disaster released more than 636 million L of crude oil into the northern Gulf of Mexico. The spill oiled upper surface water spawning…”
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A Novel Cardiotoxic Mechanism for a Pervasive Global Pollutant by Brette, Fabien, Shiels, Holly A., Galli, Gina L. J., Cros, Caroline, Incardona, John P., Scholz, Nathaniel L., Block, Barbara A.

“…The Deepwater Horizon disaster drew global attention to the toxicity of crude oil and the potential for adverse health effects amongst marine life and spill…”
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Bioretention filtration prevents acute mortality and reduces chronic toxicity for early life stage coho salmon (Oncorhynchus kisutch) episodically exposed to urban stormwater runoff by McIntyre, Jenifer K., Spromberg, Julann, Cameron, James, Incardona, John P., Davis, Jay W., Scholz, Nathaniel L.

“…As the human population of western North America continues to expand, widespread patterns of urban growth pose increasingly existential threats to certain wild…”
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Structure-activity relationships for alkyl-phenanthrenes support two independent but interacting synergistic models for PAC mixture potency by Incardona, John P., Linbo, Tiffany L., Cameron, James R., Scholz, Nathaniel L.

“…Multiple lines of evidence at whole animal, cellular and molecular levels implicate polycyclic aromatic compounds (PACs) with three rings as drivers of crude…”
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Acute Embryonic or Juvenile Exposure to Deepwater Horizon Crude Oil Impairs the Swimming Performance of Mahi-Mahi (Coryphaena hippurus) by Mager, Edward M, Esbaugh, Andrew J, Stieglitz, John D, Hoenig, Ronald, Bodinier, Charlotte, Incardona, John P, Scholz, Nathaniel L, Benetti, Daniel D, Grosell, Martin

“…The Deepwater Horizon incident likely resulted in exposure of commercially and ecologically important fish species to crude oil during the sensitive early life…”
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Sublethal exposure to crude oil during embryonic development alters cardiac morphology and reduces aerobic capacity in adult fish by Hicken, Corinne E, Linbo, Tiffany L, Baldwin, David H, Willis, Maryjean L, Myers, Mark S, Holland, Larry, Larsen, Marie, Stekoll, Michael S, Rice, Stanley D, Collier, Tracy K, Scholz, Nathaniel L, Incardona, John P

“…Exposure to high concentrations of crude oil produces a lethal syndrome of heart failure in fish embryos. Mortality is caused by cardiotoxic polycyclic…”
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Interspecies variation in the susceptibility of adult Pacific salmon to toxic urban stormwater runoff by McIntyre, Jenifer K., Lundin, Jessica I., Cameron, James R., Chow, Michelle I., Davis, Jay W., Incardona, John P., Scholz, Nathaniel L.

“…Adult coho salmon (Oncorhynchus kisutch) prematurely die when they return from the ocean to spawn in urban watersheds throughout northwestern North America…”
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The effects of weathering and chemical dispersion on Deepwater Horizon crude oil toxicity to mahi-mahi (Coryphaena hippurus) early life stages by Esbaugh, Andrew J., Mager, Edward M., Stieglitz, John D., Hoenig, Ronald, Brown, Tanya L., French, Barbara L., Linbo, Tiffany L., Lay, Claire, Forth, Heather, Scholz, Nathaniel L., Incardona, John P., Morris, Jeffrey M., Benetti, Daniel D., Grosell, Martin

“…To better understand the impact of the Deepwater Horizon (DWH) incident on commercially and ecologically important pelagic fish species, a mahi-mahi spawning…”
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Novel adverse outcome pathways revealed by chemical genetics in a developing marine fish by Sørhus, Elin, Incardona, John P, Furmanek, Tomasz, Goetz, Giles W, Scholz, Nathaniel L, Meier, Sonnich, Edvardsen, Rolf B, Jentoft, Sissel

“…Crude oil spills are a worldwide ocean conservation threat. Fish are particularly vulnerable to the oiling of spawning habitats, and crude oil causes severe…”
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Very low embryonic crude oil exposures cause lasting cardiac defects in salmon and herring by Incardona, John P., Carls, Mark G., Holland, Larry, Linbo, Tiffany L., Baldwin, David H., Myers, Mark S., Peck, Karen A., Tagal, Mark, Rice, Stanley D., Scholz, Nathaniel L.

“…The 1989 Exxon Valdez disaster exposed embryos of pink salmon and Pacific herring to crude oil in shoreline spawning habitats throughout Prince William Sound,…”
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Exxon Valdez to Deepwater Horizon: Comparable toxicity of both crude oils to fish early life stages by Incardona, John P., Swarts, Tanya L., Edmunds, Richard C., Linbo, Tiffany L., Aquilina-Beck, Allisan, Sloan, Catherine A., Gardner, Luke D., Block, Barbara A., Scholz, Nathaniel L.

“…•MC252 and Alaskan crude oils produced highly similar developmental toxicity in zebrafish embryos.•Both types of crude oil produced canonical petrogenic PAH…”
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Crude oil exposures reveal roles for intracellular calcium cycling in haddock craniofacial and cardiac development by Sørhus, Elin, Incardona, John P., Karlsen, Ørjan, Linbo, Tiffany, Sørensen, Lisbet, Nordtug, Trond, van der Meeren, Terje, Thorsen, Anders, Thorbjørnsen, Maja, Jentoft, Sissel, Edvardsen, Rolf B., Meier, Sonnich

“…Recent studies have shown that crude oil exposure affects cardiac development in fish by disrupting excitation-contraction (EC) coupling. We previously found…”
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Geologically distinct crude oils cause a common cardiotoxicity syndrome in developing zebrafish by Jung, Jee-Hyun, Hicken, Corinne E., Boyd, Daryle, Anulacion, Bernadita F., Carls, Mark G., Shim, Won Joon, Incardona, John P.

“…► Crude oils from distinct geological sources produce an overlapping cardiotoxicity syndrome in developing zebrafish embryos. ► The patterns of AHR activation…”
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Biological Responses of Pacific Herring Embryos to Crude Oil Are Quantifiable at Exposure Levels Below Conventional Limits of Quantitation for PAHs in Water and Tissues by Incardona, John P, Linbo, Tiffany L, Cameron, James R, French, Barbara L, Bolton, Jennie L, Gregg, Jacob L, Donald, Carey E, Hershberger, Paul K, Scholz, Nathaniel L

“…Pacific herring ( ), a cornerstone of marine food webs, generally spawn on marine macroalgae in shallow nearshore areas that are disproportionately at risk…”
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Differential Toxicokinetics Determines the Sensitivity of Two Marine Embryonic Fish Exposed to Iranian Heavy Crude Oil by Jung, Jee-Hyun, Kim, Moonkoo, Yim, Un Hyuk, Ha, Sung Yong, Shim, Won Joon, Chae, Young Sun, Kim, Hana, Incardona, John P, Linbo, Tiffany L, Kwon, Jung-Hwan

“…Interspecific difference in the developmental toxicity of crude oil to embryonic fish allows the prediction of injury extent to a number of resident fish…”
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