Search Results - "Inayat, Samsoon"

Neurons in the most superficial lamina of the mouse superior colliculus are highly selective for stimulus direction by Inayat, Samsoon, Barchini, Jad, Chen, Hui, Feng, Liang, Liu, Xiaorong, Cang, Jianhua

“…The superior colliculus (SC) is a layered midbrain structure important for multimodal integration and sensorimotor transformation. Its superficial layers are…”
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A Matlab-based toolbox for characterizing behavior of rodents engaged in string-pulling by Inayat, Samsoon, Singh, Surjeet, Ghasroddashti, Arashk, Qandeel, Egodage, Pramuka, Whishaw, Ian Q, Mohajerani, Majid H

“…String-pulling by rodents is a behavior in which animals make rhythmical body, head, and bilateral forearm as well as skilled hand movements to spontaneously…”
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Hippocampal conjunctive and complementary CA1 populations relate sensory events to movement by Inayat, Samsoon, McAllister, Brendan B., Whishaw, Ian Q., Mohajerani, Majid H.

“…Hippocampal CA1 neurons respond to sensory stimuli during enforced immobility, movement, and their transitions in a new conveyor belt task. Head-fixed mice…”
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Allelic variance between GRM6 mutants, Grm6nob3 and Grm6nob4 results in differences in retinal ganglion cell visual responses by Maddox, Dennis M., Vessey, Kirstan A., Yarbrough, Gary L., Invergo, Brandon M., Cantrell, Donald R., Inayat, Samsoon, Balannik, Victoria, Hicks, Wanda L., Hawes, Norman L., Byers, Shannon, Smith, Richard S., Hurd, Ron, Howell, Douglas, Gregg, Ronald G., Chang, Bo, Naggert, Jürgen K., Troy, John B., Pinto, Lawrence H., Nishina, Patsy M., McCall, Maureen A.

“…An electroretinogram (ERG) screen identified a mouse with a normal a-wave but lacking a b-wave, and as such it was designated no b-wave3 ( nob3 ). The nob3…”
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Optical-flow analysis toolbox for characterization of spatiotemporal dynamics in mesoscale optical imaging of brain activity by Afrashteh, Navvab, Inayat, Samsoon, Mohsenvand, Mostafa, Mohajerani, Majid H.

“…Wide-field optical imaging techniques constitute powerful tools to investigate mesoscale neuronal activity. The sampled data constitutes a sequence of image…”
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Low acetylcholine during early sleep is important for motor memory consolidation by Inayat, Samsoon, Qandeel, Nazariahangarkolaee, Mojtaba, Singh, Surjeet, McNaughton, Bruce L, Whishaw, Ian Q, Mohajerani, Majid H

“…Abstract The synaptic homeostasis theory of sleep proposes that low neurotransmitter activity in sleep optimizes memory consolidation. We tested this theory by…”
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Restoring neuronal chloride extrusion reverses cognitive decline linked to Alzheimer's disease mutations by Keramidis, Iason, McAllister, Brendan B, Bourbonnais, Julien, Wang, Feng, Isabel, Dominique, Rezaei, Edris, Sansonetti, Romain, Degagne, Phil, Hamel, Justin P, Nazari, Mojtaba, Inayat, Samsoon, Dudley, Jordan C, Barbeau, Annie, Froux, Lionel, Paquet, Marie-Eve, Godin, Antoine G, Mohajerani, Majid H, De Koninck, Yves

“…Disinhibition during early stages of Alzheimer's disease is postulated to cause network dysfunction and hyperexcitability leading to cognitive deficits…”
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Information-theory analysis of mouse string-pulling agrees with Fitts’s Law: Increasing task difficulty engages multiple sensorimotor modalities in a dual oscillator behavior by Sandhu, Pardeepak S., Mirza Agha, Behroo, Inayat, Samsoon, Singh, Surjeet, Ryait, Hardeep S., Mohajerani, Majid H., Whishaw, Ian Q.

“…Mouse string pulling, in which a mouse reels in a string with hand-over-hand movements, can provide insights into skilled motor behavior, neurological status,…”
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Weak-hyperactive hippocampal CA1 neurons in the prodromal stage of Alzheimer's disease in hybrid AppNL-G-F/NL-G-F × Thy1-GCaMP6s+/− mice suggest disrupted plasticity by Inayat, Samsoon, McAllister, Brendan B., Chang, HaoRan, Lacoursiere, Sean G., Whishaw, Ian Q., Sutherland, Robert J., Mohajerani, Majid H.

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Spatiotemporal structure of sensory-evoked and spontaneous activity revealed by mesoscale imaging in anesthetized and awake mice by Afrashteh, Navvab, Inayat, Samsoon, Bermudez-Contreras, Edgar, Luczak, Artur, McNaughton, Bruce L., Mohajerani, Majid H.

“…Stimuli-evoked and spontaneous brain activity propagates across the cortex in diverse spatiotemporal patterns. Despite extensive studies, the relationship…”
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Differential stimulation of the retina with subretinally injected exogenous neurotransmitter: A biomimetic alternative to electrical stimulation by Rountree, Corey M., Inayat, Samsoon, Troy, John B., Saggere, Laxman

“…Subretinal stimulation of the retina with neurotransmitters, the normal means of conveying visual information, is a potentially better alternative to…”
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Weak-hyperactive hippocampal CA1 neurons in the prodromal stage of Alzheimer's disease in hybrid App NL-G-F/NL-G-F × Thy1-GCaMP6s +/- mice suggest disrupted plasticity by Inayat, Samsoon, McAllister, Brendan B, Chang, HaoRan, Lacoursiere, Sean G, Whishaw, Ian Q, Sutherland, Robert J, Mohajerani, Majid H

“…This study investigated the impact of familial Alzheimer's disease (AD)-linked amyloid precursor protein (App) mutations on hippocampal CA1 neuronal activity…”
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Chemical stimulation of rat retinal neurons: feasibility of an epiretinal neurotransmitter-based prosthesis by Inayat, Samsoon, Rountree, Corey M, Troy, John B, Saggere, Laxman

“…No cure currently exists for photoreceptor degenerative diseases, which cause partial or total blindness in millions of people worldwide. Electrical retinal…”
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Neurons in the Most Superficial Lamina of the Mouse Superior Colliculus Are Highly Selective for Stimulus Direction by Inayat, Samsoon, Barchini, Jad, Chen, Hui, Feng, Liang, Liu, Xiaorong, Cang, Jianhua

“…The superior colliculus (SC) is a layered midbrain structure important for multimodal integration and sensorimotor transformation. Its superficial layers are…”
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Incorporation of the electrode-electrolyte interface into finite-element models of metal microelectrodes by Cantrell, Donald R, Inayat, Samsoon, Taflove, Allen, Ruoff, Rodney S, Troy, John B

“…An accurate description of the electrode-electrolyte interfacial impedance is critical to the development of computational models of neural recording and…”
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Lowering Series Resistance in Whole-Cell Patch Clamp Experiments using the Pushpen Patch Clamp Electrode by Inayat, Samsoon, Pinto, Lawrence H., Troy, John B.

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Minimizing Cytosol Dilution in Whole-Cell Patch-Clamp Experiments by Inayat, Samsoon, Pinto, Lawrence H., Troy, John B.

“…During a conventional whole-cell patch clamp experiment, diffusible cytosolic ions or molecules absent in the pipette solution can become diluted by a factor…”
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Solid-supported membrane technology for the investigation of the influenza A virus M2 channel activity by Balannik, Victoria, Obrdlik, Petr, Inayat, Samsoon, Steensen, Catrin, Wang, Jun, Rausch, Joshua M., DeGrado, William F., Kelety, Bela, Pinto, Lawrence H.

“…Influenza A virus encodes an integral membrane protein, A/M2, that forms a pH-gated proton channel that is essential for viral replication. The A/M2 channel is…”
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A Novel Electrode to Improve Whole-Cell Patch-Clamp Recording by Inayat, Samsoon

“…The whole-cell patch-clamp technique is the gold standard for studying electrophysiological properties of membrane-embedded proteins and their role in cellular…”
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A Novel Way to Go Whole Cell in Patch-Clamp Experiments by Inayat, Samsoon, Zhao, Yan, Cantrell, Donald R., Dikin, Dmitriy A., Pinto, Lawrence H., Troy, John B.

“…With a conventional patch-clamp electrode, an Ag/AgCl wire sits stationary inside the pipette. To move from the gigaseal cell-attached configuration to…”
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