Search Results - "Inatomi, O."

Expression of human cathelicidin peptide LL‐37 in inflammatory bowel disease by Kusaka, S., Nishida, A., Takahashi, K., Bamba, S., Yasui, H., Kawahara, M., Inatomi, O., Sugimoto, M., Andoh, A.

“…Summary Cathelicidin peptide LL‐37 plays an important role in the early host response against invading pathogens via its broad‐spectrum anti‐microbial…”
Get full text

Letter: CYP3A4/5 genotype status and outcome of vonoprazan‐containing Helicobacter pylori eradication therapy in Japan by Sugimoto, M., Ban, H., Hira, D., Kamiya, T., Otsuka, T., Inatomi, O., Bamba, S., Terada, T., Andoh, A.

“…Linked ContentThis article is linked to Sakurai et al and Mori and Okamoto papers. To view this article visit https://doi.org/10.1111/apt.13325…”
Get full text

Letter: a potassium‐competitive acid blocker vs a proton pump inhibitor for healing endoscopic submucosal dissection‐induced artificial ulcers after treatment of gastric neoplasms by Ban, H., Sugimoto, M., Otsuka, T., Murata, M., Nakata, T., Hasegawa, H., Fukuda, M., Inatomi, O., Bamba, S., Kushima, R., Andoh, A.

“…Linked ContentThis article is linked to Kagawa et al and Iwamuro and Inaba papers. To view these articles visit https://doi.org/10.1111/apt.14213 and…”
Get full text

Thiopurine Use During Pregnancy Has Deleterious Effects on Offspring in Nudt15R138C Knock-In Mice by Imai, T., Kawahara, M., Tatsumi, G., Yamashita, N., Nishishita-Asai, A., Inatomi, O., Masamune, A., Kakuta, Y., Andoh, A.

Get full text

Interleukin-22, a Member of the IL-10 Subfamily, Induces Inflammatory Responses in Colonic Subepithelial Myofibroblasts by Andoh, Akira, Zhang, Zhuobin, Inatomi, Osamu, Fujino, Sanae, Deguchi, Yasuyuki, Araki, Yoshio, Tsujikawa, Tomoyuki, Kitoh, Katsuyuki, Kim–Mitsuyama, Shokei, Takayanagi, Atsushi, Shimizu, Nobuyoshi, Fujiyama, Yoshihide

“…Background & Aims: Interleukin (IL)-22, a member of the IL-10 subfamily, is a recently identified T-cell-derived cytokine. We investigated IL-22 expression in…”
Get full text

Letter: CYP 3A4/5 genotype status and outcome of vonoprazan‐containing Helicobacter pylori eradication therapy in Japan by Sugimoto, M., Ban, H., Hira, D., Kamiya, T., Otsuka, T., Inatomi, O., Bamba, S., Terada, T., Andoh, A.

“…Linked Content This article is linked to Sakurai et al and Mori and Okamoto papers. To view this article visit https://doi.org/10.1111/apt.13325 …”
Get full text

Thiopurine Use During Pregnancy Has Deleterious Effects on Offspring in Nudt15 R138C Knock-In Mice by Imai, T, Kawahara, M, Tatsumi, G, Yamashita, N, Nishishita-Asai, A, Inatomi, O, Masamune, A, Kakuta, Y, Andoh, A

Get full text

PF458 THIOPURINE‐MEDIATED IMPAIRMENT OF HEMATOPOIEIC STEM AND PROGENITOR CELLS IN NUDT15R138C KNOCK‐IN MICE AND POTENTIALITY OF NUDT15 GENOTYPE‐BASED PRECISION MEDICINE FOR ACUTE LEUKEMIA by Tatsumi, G., Kawahara, M., Imai, T., Nishishita‐Asai, A., Nishida, A., Inatomi, O., Yokoyama, A., Kakuta, Y., Kito, K., Andoh, A.

“…Background: Thiopurines are largely used as effective antileukemic agents, but the use of thiopurines is frequently limited by severe adverse effects including…”
Get full text

Expression of interleukin 1-like cytokine interleukin 33 and its receptor complex (ST2L and IL1RAcP) in human pancreatic myofibroblasts by Nishida, Atsushi, Andoh, Akira, Imaeda, Hirotsugu, Inatomi, Osamu, Shiomi, Hisanori, Fujiyama, Yoshihide

“…Interleukin 33 (IL33) is a cytokine belonging to the IL1 family and it binds to a complex of the ST2L/IL1 receptor accessory protein (IL1RAcP). To define the…”
Get more information

Serum selenoprotein-P levels in patients with inflammatory bowel disease by Andoh, Akira, Hirashima, Masaki, Maeda, Hiroaki, Hata, Kazunori, Inatomi, Osamu, Tsujikawa, Tomoyuki, Sasaki, Masaya, Takahashi, Kazuhiko, Fujiyama, Yoshihide

“…Selenoprotein-P is a selenium-rich serum protein that carries more than 50% of serum selenium. We evaluated changes in serum selenoprotein-P levels in patients…”
Get full text

Immunohistochemical study of chymase-positive mast cells in inflammatory bowel disease by ANDOH, Akira, DEGUCHI, Yasuyuki, INATOMI, Osamu, YAGI, Yuki, BAMBA, Shigeki, TSUJIKAWA, Tomoyuki, FUJIYAMA, Yoshihide

“…Mast cell-derived chymase promotes inflammatory responses and tissue fibrosis. Although previous studies have reported changes in the number of mucosal mast…”
Get full text

Interleukin-17 and lipopolysaccharides synergistically induce cyclooxygenase-2 expression in human intestinal myofibroblasts by ZHANG, ZHUOBIN, ANDOH, AKIRA, INATOMI, OSAMU, BAMBA, SHIGEKI, TAKAYANAGI, ATSUSHI, SHIMIZU, NOBUYOSHI, FUJIYAMA, YOSHIHIDE

“…Background:  Colonic subepithelial myofibroblasts (SEMF) play a role in the modulation of mucosal inflammatory responses via the secretion of various…”
Get full text

Prognostic factors for colectomy in refractory ulcerative colitis treated with calcineurin inhibitors by BAMBA, SHIGEKI, ANDOH, AKIRA, IMAEDA, HIROTSUGU, BAN, HIROMITSU, KOBORI, AYAKO, MOCHIZUKI, YOUSUKE, SHIOYA, MAKOTO, NISHIMURA, TAKASHI, INATOMI, OSAMU, SASAKI, MASAYA, SAITOH, YASUHARU, TSUJIKAWA, TOMOYUKI, FUJIYAMA, YOSHIHIDE

“…Calcineurin inhibitors (CNIs) such as cyclosporin A (CSA) and tacrolimus (FK506) are efficacious in patients with steroid-refractory or steroid-dependent…”
Get full text

Interleukin-17 augments tumor necrosis factor-alpha-induced granulocyte and granulocyte/macrophage colony-stimulating factor release from human colonic myofibroblasts by Andoh, Akira, Yasui, Hirofumi, Inatomi, Osamu, Zhang, Zhuobin, Deguchi, Yasuyuki, Hata, Kazunori, Araki, Yoshio, Tsujikawa, Tomoyuki, Kitoh, Katsuyuki, Kim-Mitsuyama, Shokei, Takayanagi, Atsushi, Shimizu, Nobuyoshi, Fujiyama, Yoshihide

“…Interleukin (IL)-17 is a newly identified T-cell-specific cytokine. In this study, we investigated the effects of IL-17 on colony-stimulating factor (CSF)…”
Get full text

Butyrate blocks interferon-gamma-inducible protein-10 release in human intestinal subepithelial myofibroblasts by Inatomi, Osamu, Andoh, Akira, Kitamura, Ken-Ichi, Yasui, Hirofumi, Zhang, Zhuobin, Fujiyama, Yoshihide

“…Interferon (IFN)-gamma-inducible protein (IP)-10 is a chemoattractant for CXCR 3-expressing T lymphocytes and monocytes. IP-10 has been reported to mediate…”
Get full text

Development of dextran sulfate sodium-induced colitis is aggravated in mice genetically deficient for complement C5 by Deguchi, Yasuyuki, Andoh, Akira, Inatomi, Osamu, Araki, Yoshio, Hata, Kazunori, Tsujikawa, Tomoyuki, Kitoh, Katsuyuki, Fujiyama, Yoshihide

“…The complement system is a potent effector of innate immunity. To elucidate the pathophysiological role of the complement system in inflammatory bowel disease…”
Get more information

Role of fibroblast growth factor-2 in the expression of matrix metalloproteinases and tissue inhibitors of metalloproteinases in human intestinal myofibroblasts by Yasui, Hirofumi, Andoh, Akira, Bamba, Shigeki, Inatomi, Osamu, Ishida, Hideaki, Fujiyama, Yoshihide

“…The coordinated expression of matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs) plays a crucial role in tissue remodeling…”
Get more information

Leukocytapheresis Therapy Modulates Circulating T cell Subsets in Patients With Ulcerative Colitis by Andoh, Akira, Tsujikawa, Tomoyuki, Inatomi, Osamu, Deguchi, Yasuyuki, Sasaki, Masaya, Obata, Hirozumi, Mitsuyama, Keiichi, Fujiyama, Yoshihide

“…:  The aim of this study was to elucidate the molecular mechanisms responsible for the therapeutic effects of leukocytapheresis (LCAP). We investigated the…”
Get full text

Suppression of Inflammatory Cytokine Secretion by Granulocyte/Monocyte Adsorptive Apheresis in Active Ulcerative Colitis by Andoh, Akira, Tsujikawa, Tomoyuki, Inatomi, Osamu, Deguchi, Yasuyuki, Hata, Kazunori, Kitoh, Katsuyuki, Sasaki, Masaya, Mitsuyama, Keiichi, Fujiyama, Yoshihide

“…:  To elucidate the molecular mechanisms involved in the therapeutic effects of granulocyte/monocyte adsorption apheresis, changes were investigated in the…”
Get full text

Fibroblast growth factor-2 stimulates interleukin-6 secretion in human pancreatic periacinar myofibroblasts by Andoh, Akira, Bamba, Shigeki, Fujino, Sanae, Inatomi, Osamu, Zhang, Zhuobin, Kim, Shokei, Takayanagi, Atsushi, Shimizu, Nobuyoshi, Fujiyama, Yoshihide

“…Fibroblast growth factor-2 (FGF-2) plays an important role in the pathophysiology of acute and chronic pancreatitis. In the present study, to evaluate the…”
Get full text