Search Results - "Inagaki, Naoyuki"

Actin Waves: Origin of Cell Polarization and Migration? by Inagaki, Naoyuki, Katsuno, Hiroko

“…Actin filaments and associated proteins undergo wave-like movement in various cell types. Recent studies with cutting-edge analyses, including live-cell…”
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Mechanical regulation of synapse formation and plasticity by Minegishi, Takunori, Kastian, Ria Fajarwati, Inagaki, Naoyuki

“…Dendritic spines are small protrusions arising from dendrites and constitute the major compartment of excitatory post-synapses. They change in number, shape,…”
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Rab33a and Rab33ba mediate the outgrowth of forebrain commissural axons in the zebrafish brain by Huang, Liguo, Urasaki, Akihiro, Inagaki, Naoyuki

“…Rab small GTPases play key roles in intracellular membrane trafficking. Rab33a promotes axon outgrowth of cultured rat hippocampal neurons by mediating the…”
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Forces to Drive Neuronal Migration Steps by Minegishi, Takunori, Inagaki, Naoyuki

“…To establish and maintain proper brain architecture and elaborate neural networks, neurons undergo massive migration. As a unique feature of their migration,…”
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Mechanosensitive axon outgrowth mediated by L1-laminin clutch interface by Abe, Kouki, Baba, Kentarou, Huang, Liguo, Wei, Koay Teng, Okano, Kazunori, Hosokawa, Yoichiroh, Inagaki, Naoyuki

“…Mechanical properties of the extracellular environment modulate axon outgrowth. Growth cones at the tip of extending axons generate traction force for axon…”
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Shootin1b Mediates a Mechanical Clutch to Produce Force for Neuronal Migration by Minegishi, Takunori, Uesugi, Yasuyuki, Kaneko, Naoko, Yoshida, Wataru, Sawamoto, Kazunobu, Inagaki, Naoyuki

“…As an essential step for brain morphogenesis, neurons migrate via mechanical interactions with components of their environment such as neighboring cells and…”
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Actin Migration Driven by Directional Assembly and Disassembly of Membrane-Anchored Actin Filaments by Katsuno, Hiroko, Toriyama, Michinori, Hosokawa, Yoichiroh, Mizuno, Kensaku, Ikeda, Kazushi, Sakumura, Yuichi, Inagaki, Naoyuki

“…Actin and actin-associated proteins migrate within various cell types. To uncover the mechanism of their migration, we analyzed actin waves, which translocate…”
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Dephosphorylation of neural wiring protein shootin1 by PP1 phosphatase regulates netrin-1-induced axon guidance by Kastian, Ria Fajarwati, Baba, Kentarou, Kaewkascholkul, Napol, Sasaki, Hisashi, Watanabe, Rikiya, Toriyama, Michinori, Inagaki, Naoyuki

“…Axon pathfinding is an essential step in neuronal network formation. Shootin1a is a clutch-linker molecule that is mechanically involved in axon outgrowth and…”
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Adhesion-clutch between DCC and netrin-1 mediates netrin-1-induced axonal haptotaxis by Qiu, Zhen, Minegishi, Takunori, Aoki, Daichi, Abe, Kouki, Baba, Kentarou, Inagaki, Naoyuki

“…The growth cone, a motile structure located at the tip of growing axons, senses extracellular guidance cues and translates them into directional forces that…”
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An Artificial Amphiphilic Peptide Promotes Endocytic Uptake by Inducing Membrane Curvature by Masuda, Toshihiro, Hirose, Hisaaki, Baba, Kentarou, Walrant, Astrid, Sagan, Sandrine, Inagaki, Naoyuki, Fujimoto, Toyoshi, Futaki, Shiroh

“…Membrane curvature plays a pivotal role in cellular life, including cellular uptake and membrane trafficking. The modulation of membrane curvature provides a…”
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Shootin1a-mediated actin-adhesion coupling generates force to trigger structural plasticity of dendritic spines by Kastian, Ria Fajarwati, Minegishi, Takunori, Baba, Kentarou, Saneyoshi, Takeo, Katsuno-Kambe, Hiroko, Saranpal, Singh, Hayashi, Yasunori, Inagaki, Naoyuki

“…Dendritic spines constitute the major compartments of excitatory post-synapses. They undergo activity-dependent enlargement, which is thought to increase the…”
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Structural basis of cargo recognition by the myosin-X MyTH4-FERM domain by Hirano, Yoshinori, Hatano, Taiki, Takahashi, Aya, Toriyama, Michinori, Inagaki, Naoyuki, Hakoshima, Toshio

“…Myosin‐X is an important unconventional myosin that is critical for cargo transportation to filopodia tips and is also utilized in spindle assembly by…”
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Rab33a mediates anterograde vesicular transport for membrane exocytosis and axon outgrowth by Nakazawa, Hitomi, Sada, Tadayuki, Toriyama, Michinori, Tago, Kenji, Sugiura, Tadao, Fukuda, Mitsunori, Inagaki, Naoyuki

“…Axon outgrowth requires plasma membrane expansion, which results from post-Golgi vesicular transport and fusion. However, the molecular mechanisms regulating…”
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Simultaneous analyses of clutch coupling and actin polymerization in dendritic spines of rodent hippocampal neurons during chemical LTP by Kastian, Ria Fajarwati, Minegishi, Takunori, Inagaki, Naoyuki

“…Dendritic spine enlargement by synaptic activation is thought to increase synaptic efficacy underlying learning and memory. This process requires forces…”
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A diffusion-based neurite length-sensing mechanism involved in neuronal symmetry breaking by Toriyama, Michinori, Inagaki, Naoyuki, Sakumura, Yuichi, Ishii, Shin, Shimada, Tadayuki

“…Although there has been significant progress in understanding the molecular signals that change cell morphology, mechanisms that cells use to monitor their…”
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Identification of a shootin1 isoform expressed in peripheral tissues by Higashiguchi, Yasuna, Katsuta, Kazuhiro, Minegishi, Takunori, Yonemura, Shigenobu, Urasaki, Akihiro, Inagaki, Naoyuki

“…Shootin1 is a brain-specific cytoplasmic protein involved in neuronal polarity formation and axon outgrowth. It accumulates at the leading edge of axonal…”
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Gradient-reading and mechano-effector machinery for netrin-1-induced axon guidance by Baba, Kentarou, Yoshida, Wataru, Toriyama, Michinori, Shimada, Tadayuki, Manning, Colleen F, Saito, Michiko, Kohno, Kenji, Trimmer, James S, Watanabe, Rikiya, Inagaki, Naoyuki

“…Growth cones navigate axonal projection in response to guidance cues. However, it is unclear how they can decide the migratory direction by transducing the…”
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Shootins mediate collective cell migration and organogenesis of the zebrafish posterior lateral line system by Urasaki, Akihiro, Morishita, Seiya, Naka, Kosuke, Uozumi, Minato, Abe, Kouki, Huang, Liguo, Watase, Emiko, Nakagawa, Osamu, Kawakami, Koichi, Matsui, Takaaki, Bessho, Yasumasa, Inagaki, Naoyuki

“…The zebrafish sensory posterior lateral line is an excellent model system to study collective cell migration and organogenesis. Shootin1 is a cytoplasmic…”
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Shootin1: a protein involved in the organization of an asymmetric signal for neuronal polarization by Toriyama, Michinori, Shimada, Tadayuki, Kim, Ki Bum, Mitsuba, Mari, Nomura, Eiko, Katsuta, Kazuhiro, Sakumura, Yuichi, Roepstorff, Peter, Inagaki, Naoyuki

“…Neurons have the remarkable ability to polarize even in symmetrical in vitro environments. Although recent studies have shown that asymmetric intracellular…”
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Singar1, a Novel RUN Domain-containing Protein, Suppresses Formation of Surplus Axons for Neuronal Polarity by Mori, Tatsuya, Wada, Tomoe, Suzuki, Takahiro, Kubota, Yoshitsugu, Inagaki, Naoyuki

“…Although neuronal functions depend on their robust polarity, the mechanisms that ensure generation and maintenance of only a single axon remain poorly…”
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