Search Results - "Inagaki, Emi"

Effect of oral administration of nicotinamide mononucleotide on clinical parameters and nicotinamide metabolite levels in healthy Japanese men by Irie, Junichiro, Inagaki, Emi, Fujita, Masataka, Nakaya, Hideaki, Mitsuishi, Masanori, Yamaguchi, Shintaro, Yamashita, Kazuya, Shigaki, Shuhei, Ono, Takashi, Yukioka, Hideo, Okano, Hideyuki, Nabeshima, Yo-ichi, Imai, Shin-ichiro, Yasui, Masato, Tsubota, Kazuo, Itoh, Hiroshi

“…Recent studies have revealed that decline in cellular nicotinamide adenine dinucleotide (NAD+) levels causes aging-related disorders and therapeutic approaches…”
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The Cornea: An Ideal Tissue for Regenerative Medicine by Shimmura, Shigeto, Inagaki, Emi, Hirayama, Masatoshi, Hatou, Shin

“…Regenerative medicine is a highly anticipated field with hopes to provide cures for previously uncurable diseases such as spinal cord injuries and retinal…”
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Corneal Endothelial Regeneration Using Mesenchymal Stem Cells Derived from Human Umbilical Cord by Yamashita, Kazuya, Inagaki, Emi, Hatou, Shin, Higa, Kazunari, Ogawa, Akiko, Miyashita, Hideyuki, Tsubota, Kazuo, Shimmura, Shigeto

“…Corneal blindness is the third leading cause of blindness in the world, and one of the main etiologies is dysfunction of the corneal endothelium. Current…”
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Accelerated neuronal aging in vitro ∼melting watch by Inagaki, Emi, Yoshimatsu, Sho, Okano, Hideyuki

“…In developed countries, the aging of the population and the associated increase in age-related diseases are causing major unresolved medical, social, and…”
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Safety and efficacy of long-term nicotinamide mononucleotide supplementation on metabolism, sleep, and nicotinamide adenine dinucleotide biosynthesis in healthy, middle-aged Japanese men by Yamaguchi, Shintaro, Irie, Junichiro, Mitsuishi, Masanori, Uchino, Yuichi, Nakaya, Hideaki, Takemura, Ryo, Inagaki, Emi, Kosugi, Shotaro, Okano, Hideyuki, Yasui, Masato, Tsubota, Kazuo, Hayashi, Kaori, Yoshino, Jun, Itoh, Hiroshi

“…Obesity and aging are major risk factors for several life-threatening diseases. Accumulating evidence from both rodents and humans suggests that the levels of…”
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Ketone body 3‐hydroxybutyrate mimics calorie restriction via the Nrf2 activator, fumarate, in the retina by Izuta, Yusuke, Imada, Toshihiro, Hisamura, Ryuji, Oonishi, Erina, Nakamura, Shigeru, Inagaki, Emi, Ito, Masataka, Soga, Tomoyoshi, Tsubota, Kazuo

“…Summary Calorie restriction (CR) being the most robust dietary intervention provides various health benefits. D‐3‐hydroxybutyrate (3HB), a major physiological…”
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Transplantation of iPSC-derived corneal endothelial substitutes in a monkey corneal edema model by Hatou, Shin, Sayano, Tomoko, Higa, Kazunari, Inagaki, Emi, Okano, Yuji, Sato, Yasunori, Okano, Hideyuki, Tsubota, Kazuo, Shimmura, Shigeto

“…[Display omitted] •Corneal endothelial-like cells (CECSi cells) from several iPS cell lines.•Cryopreserved and thawed CECSi cells, expressing N-cadherin and…”
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The Semaphorin 3A inhibitor SM-345431 preserves corneal nerve and epithelial integrity in a murine dry eye model by Yamazaki, Risa, Yamazoe, Katsuya, Yoshida, Satoru, Hatou, Shin, Inagaki, Emi, Okano, Hideyuki, Tsubota, Kazuo, Shimmura, Shigeto

“…Dry eye disease (DED) is a common disorder causing discomfort and ocular fatigue. Corneal nerves are compromised in DED, which may further cause loss of…”
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A Comprehensive Assessment of Tear-Film-Oriented Diagnosis (TFOD) in a Dacryoadenectomy Dry Eye Model by Sakakura, Saki, Inagaki, Emi, Ochiai, Yuichiro, Yamamoto, Masatoshi, Takai, Naofumi, Nagata, Taeko, Higa, Kazunari, Sato, Yasunori, Toshida, Hiroshi, Murat, Dogru, Hirayama, Masatoshi, Ogawa, Yoko, Negishi, Kazuno, Shimmura, Shigeto

“…Tear film instability is a major cause of dry eye disease. In order to treat patients with short tear film breakup time (TBUT)-type dry eye, the development of…”
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MSCs Become Collagen-Type I Producing Cells with Different Phenotype in Allogeneic and Syngeneic Bone Marrow Transplantation by Rusch, Robert Maximilian, Ogawa, Yoko, Sato, Shinri, Morikawa, Satoru, Inagaki, Emi, Shimizu, Eisuke, Tsubota, Kazuo, Shimmura, Shigeto

“…Mesenchymal stem cells (MSCs) have been widely used in therapeutic applications for many decades. However, more and more evidence suggests that factors such as…”
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Long-term homeostasis and wound healing in an in vitro epithelial stem cell niche model by Miyashita, Hideyuki, Niwano, Hiroko, Yoshida, Satoru, Hatou, Shin, Inagaki, Emi, Tsubota, Kazuo, Shimmura, Shigeto

“…Cultures of epithelial cells are limited by the proliferative capacity of primary cells and cell senescence. Herein we show that primary human epithelial cell…”
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Skin‐Derived Precursors as a Source of Progenitors for Corneal Endothelial Regeneration by Inagaki, Emi, Hatou, Shin, Higa, Kazunari, Yoshida, Satoru, Shibata, Shinsuke, Okano, Hideyuki, Tsubota, Kazuo, Shimmura, Shigeto

“…Corneal blindness is the fourth leading cause of blindness in the world. Current treatment is allogenic corneal transplantation, which is limited by shortage…”
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The Anterior Eye Chamber as a Visible Medium for In Vivo Tumorigenicity Tests by Inagaki, Emi, Arai, Eri, Hatou, Shin, Sayano, Tomoko, Taniguchi, Hiroko, Negishi, Kazuno, Kanai, Yae, Sato, Yasunori, Okano, Hideyuki, Tsubota, Kazuo, Shimmura, Shigeto

“…Pluripotent stem cell (PSC)-based cell therapies have increased steadily over the past few years, and assessing the risk of tumor formation is a high priority…”
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Development of a Transgenic Mouse with R124H Human TGFBI Mutation Associated with Granular Corneal Dystrophy Type 2 by Yamazoe, Katsuya, Yoshida, Satoru, Yasuda, Miyuki, Hatou, Shin, Inagaki, Emi, Ogawa, Yoko, Tsubota, Kazuo, Shimmura, Shigeto

“…To investigate the phenotype and predisposing factors of a granular corneal dystrophy type 2 transgenic mouse model. Human TGFBI cDNA with R124H mutation was…”
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Antitubercular Activity of Disulfiram, an Antialcoholism Drug, against Multidrug- and Extensively Drug-Resistant Mycobacterium tuberculosis Isolates by HORITA, Yasuhiro, TAKII, Takemasa, MAKINO, Toshiaki, MIZUKAMI, Hajime, HASEGAWA, Tomohiro, YAMAMOTO, Ryuji, ONOZAKI, Kikuo, YAGI, Tetsuya, OGAWA, Kenji, FUJIWARA, Nagatoshi, INAGAKI, Emi, KREMER, Laurent, SATO, Yasuo, KUROISHI, Ryuji, LEE, Yoosa

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Non-apoptotic regulated cell death in Fuchs endothelial corneal dystrophy by Sakakura, Saki, Inagaki, Emi, Sayano, Tomoko, Yamazaki, Risa, Fusaki, Noemi, Hatou, Shin, Hirayama, Masatoshi, Tsubota, Kazuo, Negishi, Kazuno, Okano, Hideyuki, Shimmura, Shigeto

“…IntroductionFuchs endothelial corneal dystrophy (FECD) is the leading cause of corneal blindness in developed countries. Corneal endothelial cells in FECD are…”
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Expression and distribution of claudin subtypes in human corneal endothelium by Inagaki, Emi, Hatou, Shin, Yoshida, Satoru, Miyashita, Hideyuki, Tsubota, Kazuo, Shimmura, Shigeto

“…To investigate the expression pattern of claudins in human corneal endothelium, and to evaluate the functional role of the claudin-10b subtype. Corneal…”
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Validation of Na,K-ATPase pump function of corneal endothelial cells for corneal regenerative medicine by Hatou, Shin, Higa, Kazunari, Inagaki, Emi, Yoshida, Satoru, Kimura, Erika, Hayashi, Ryuhei, Tsujikawa, Motokazu, Tsubota, Kazuo, Nishida, Kohji, Shimmura, Shigeto

“…Tissue-engineering approaches to cultivate corneal endothelial cells (CECs) or induce CECs from stem cells are under investigation for the treatment of…”
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The Cornea: An Ideal Tissue for Regenerative Medicine by Shimmura, Shigeto, Inagaki, Emi, Hirayama, Masatoshi, Hatou, Shin

“…Regenerative medicine is a highly anticipated field with hopes to provide cures for previously uncurable diseases such as spinal cord injuries and retinal…”
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Functional corneal endothelium derived from corneal stroma stem cells of neural crest origin by retinoic acid and Wnt/β-catenin signaling by Hatou, Shin, Yoshida, Satoru, Higa, Kazunari, Miyashita, Hideyuki, Inagaki, Emi, Okano, Hideyuki, Tsubota, Kazuo, Shimmura, Shigeto

“…Corneal endothelial dysfunction remains a major indication for corneal transplantation. Both corneal endothelial cells and stromal cells originate from the…”
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