Search Results - "Inaba, Mutsumi"

REV-ERB agonist suppresses IL-17 production in γδT cells and improves psoriatic dermatitis in a mouse model by Wang, Shangyi, Kozai, Mina, Mita, Hironobu, Cai, Zimeng, Masum, Md. Abdul, Ichii, Osamu, Takada, Kensuke, Inaba, Mutsumi

“…Psoriasis is a chronic inflammatory skin disease characterized by epidermal hyperplasia and cellular infiltration. Studies have shown that disease development…”
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Roles of tumor necrosis factor-like ligand 1A in γδT-cell activation and psoriasis pathogenesis by Wang, Shangyi, Kozai, Mina, Hiraishi, Masaya, Rubel, Md Zahir Uddin, Ichii, Osamu, Inaba, Mutsumi, Matsuo, Kazuhiro, Takada, Kensuke

“…Interleukin (IL)-17-producing γδT (γδT17) cells mediate inflammatory responses in barrier tissues. Dysregulated γδT17 cell activation can lead to the…”
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Modulatory roles of NHERF1 and NHERF2 in cell surface expression of the glutamate transporter GLAST by Sato, Kota, Otsu, Wataru, Otsuka, Yayoi, Inaba, Mutsumi

“…► NHERF1 and NHERF2 differentially interact with the glutamate transporter, GLAST. ► NHERF1 interacts with GLAST in the ER to facilitate the ER exit of GLAST…”
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The covalent modification of spectrin in red cell membranes by the lipid peroxidation product 4-hydroxy-2-nonenal by Arashiki, Nobuto, Otsuka, Yayoi, Ito, Daisuke, Yang, Mira, Komatsu, Tomohiko, Sato, Kota, Inaba, Mutsumi

“…Spectrin strengthens the red cell membrane through its direct association with membrane lipids and through protein–protein interactions. Spectrin loss reduces…”
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Clathrin-mediated Endocytosis of Mammalian Erythroid AE1 Anion Exchanger Facilitated by a YXXΦ or a Noncanonical YXXXΦ Motif in the N-Terminal Stretch by WANG, Chen-Chi, SATO, Kota, OTSUKA, Yayoi, OTSU, Wataru, INABA, Mutsumi

“…To explore the roles of the conserved YXXΦ-type motif in the erythroid-specific N-terminal stretch of anion exchanger 1 (AE1), cell surface expression and…”
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A simple method for enrichment of polychromatic erythroblasts from rat bone marrow, and their proliferation and maturation in vitro by Asano, Hiroyuki, Deguchi, Yoshihito, Kawamura, Satoshi, Inaba, Mutsumi

“…To evaluate the effects of a variety of chemical, biological and physiological stimuli on erythropoiesis, in vitro assays using erythroid progenitor cells from…”
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Bcl-xL and Mcl-1 are involved in prevention of in vitro apoptosis in rat late-stage erythroblasts derived from bone marrow by Asano, Hiroyuki, Fukunaga, Satoki, Deguchi, Yoshihito, Kawamura, Satoshi, Inaba, Mutsumi

“…Apoptosis controls erythroid homeostasis by balancing survival and death of erythroid cells. The mitochondrial pathway of apoptosis involves regulation of…”
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Parallel Reductions in Stomatin and Na,K-ATPase through the Exosomal Pathway during Reticulocyte Maturation in Dogs: Stomatin as a Genotypic and Phenotypic Marker of High K+ and Low K+ Red Cells by KOMATSU, Tomohiko, SATO, Kota, OTSUKA, Yayoi, ARASHIKI, Nobuto, TANAKA, Kohei, TAMAHARA, Satoshi, ONO, Ken-ichiro, INABA, Mutsumi

“…Dogs can be divided into two genetic groups (a minor HK phenotype and a major LK phenotype) based on erythrocyte monovalent cation concentrations, which are…”
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Clathrin-mediated Endocytosis of Mammalian Erythroid AE1 Anion Exchanger Facilitated by a YXX.PHI. or a Noncanonical YXXX.PHI. Motif in the N-Terminal Stretch by WANG, Chen-Chi, SATO, Kota, OTSUKA, Yayoi, OTSU, Wataru, INABA, Mutsumi

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Autoimmunity against a Tissue Kallikrein in IQI/Jic Mice by Takada, Kensuke, Takiguchi, Mitsuyoshi, Konno, Akihiro, Inaba, Mutsumi

“…We have recently characterized IQI/Jic mice as a model for Sjögren's syndrome (SS), a chronic autoimmune disease in humans. In SS, local lymphocytic…”
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Cell surface expression and internalization of the murine erythroid AE1 anion exchanger tagged with an extracellular FLAG epitope by Wang, Chen-Chi, Sato, Kota, Otsuka, Yayoi, Inaba, Mutsumi

“…Anion exchanger 1 (AE1) is the most abundant integral membrane protein in red cells and is essential for maintaining red cell mechanical stability. However,…”
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Structural implications of the EL(K/Q)(L/C)LD(A/G)DD sequence in the C-terminal cytoplasmic tail for proper targeting of anion exchanger 1 to the plasma membrane by Adachi, H., Hokkaido Univ., Sapporo (Japan), Ito, D, Kurooka, T, Otsuka, Y, Arashiki, N, Sato, K, Inaba, M

“…While the C-terminal cytoplasmic tail of anion exchanger 1 (AE1, band 3) has been reported to possess important physiological roles, including one for proper…”
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Diagnostic ultrasound of polypoid cystitis in dogs by Takiguchi, M. (Rakuno Gakuen Univ., Ebetsu, Hokkaido (Japan)), Inaba, M

“…Polypoid cystitis is a rare disease of the urinary bladder in dogs characterized by chronic inflammation, epithelial proliferation, and development of a…”
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Extrusion of Na, K-ATPase and transferrin receptor with lipid raft-associated proteins in different populations of exosomes during reticulocyte maturation in dogs by Komatsu, T., Hokkaido Univ., Sapporo (Japan), Arashiki, N, Otsuka, Y, Sato, K, Inaba, M

“…The present study characterizes canine reticulocyte exosomes. Exosomes are small membrane vesicles involved in membrane remodeling that are released from…”
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Different Effects on the Inflammatory Lesions in the Lacrimal and Salivary Glands after Neonatal Thymectomy in IQI/Jic Mice, a Model for Sjögren's Syndrome by TAKADA, Kensuke, TAKIGUCHI, Mitsuyoshi, INABA, Mutsumi

“…Thymectomy on day 3 after birth (D3Tx) is understood to eliminate CD4+CD25+ regulatory T cells (Treg) from the peripheral T cell repertoire in rodents, leading…”
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ROR agonist hampers the proliferation and survival of postactivated CD8+ T cells through the downregulation of cholesterol synthesis‐related genes by Cai, Zimeng, Ishibashi, Taishin, Kozai, Mina, Mita, Hironobu, Wang, Shangyi, Takada, Kensuke, Inaba, Mutsumi

“…Cholesterol is a major component of the lipid bilayers of cellular membranes. The synthesis of cholesterol is acutely elevated during T‐cell activation to…”
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Lumenal localization in the endoplasmic reticulum of the C-terminal tail of an AE1 mutant responsible for hereditary spherocytosis in cattle by Ito, D.(Hokkaido Univ., Sapporo (Japan)), Otsuka, Y, Koshino, I, Inaba, M

“…An R664X nonsense mutant AE1 is responsible for dominant hereditary spherocytosis in cattle and is degraded by the proteasomal endoplasmic reticulum-associated…”
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Identification of genes for two major sialoglycoproteins, glycophorin A and glycophorin C in canine red cell membranes by Sato, K.(Hokkaido Univ., Sapporo (Japan)), Otsuka, Y, Arashiki, N, Komatsu, T, Wang, C.C, Tamahara, S, Inaba, M

“…Glycophorins are the major sialoglycoproteins in red blood cell membranes, possessing various physiological and pathological roles. We examined membrane…”
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Genetic Diagnosis of Claudin-16 Deficiency and Sex Determination in Bovine Preimplantation Embryos by HIRAYAMA, Hiroki, KAGEYAMA, Soichi, MORIYASU, Satoru, HIRANO, Takashi, SUGIMOTO, Yoshikazu, KOBAYASHI, Naohiko, INABA, Mutsumi, SAWAI, Ken, ONOE, Sadao, MINAMIHASHI, Akira

“…The reaction conditions consisted of initial denaturing at 95 C for 15 min followed by 45 cycles of 97 C for 30 sec, 56 C for 90 sec and 72 C for 30 sec…”
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Membrane skeleton hyperstability due to a novel alternatively spliced 4.1R can account for ellipsoidal camelid red cells with decreased deformability by Chen, Yuqi, Miyazono, Kosuke, Otsuka, Yayoi, Kanamori, Mariko, Yamashita, Aozora, Arashiki, Nobuto, Matsumoto, Takehisa, Takada, Kensuke, Sato, Kota, Mohandas, Narla, Inaba, Mutsumi

“…The red blood cells (RBCs) of vertebrates have evolved into two basic shapes, with nucleated nonmammalian RBCs having a biconvex ellipsoidal shape and anuclear…”
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