Search Results - "Inaba, Kayo"
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Tracking and quantification of dendritic cell migration and antigen trafficking between the skin and lymph nodes
Published in Scientific reports (12-08-2014)“…Skin-derived dendritic cells (DCs) play a crucial role in the maintenance of immune homeostasis due to their role in antigen trafficking from the skin to the…”
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HTLV-1 bZIP Factor Enhances T-Cell Proliferation by Impeding the Suppressive Signaling of Co-inhibitory Receptors
Published in PLoS pathogens (03-01-2017)“…Human T-cell leukemia virus type 1 (HTLV-1) causes adult T-cell leukemia-lymphoma (ATL) and inflammatory diseases. To enhance cell-to-cell transmission of…”
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Langerhans cells are critical in epicutaneous sensitization with protein antigen via thymic stromal lymphopoietin receptor signaling
Published in Journal of allergy and clinical immunology (01-04-2012)“…Background The clarification of cutaneous dendritic cell subset and the role of thymic stromal lymphopoietin (TSLP) signaling in epicutaneous sensitization…”
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Inducible ablation of mouse Langerhans cells diminishes but fails to abrogate contact hypersensitivity
Published in The Journal of cell biology (23-05-2005)“…Langerhans cells (LC) form a unique subset of dendritic cells (DC) in the epidermis but so far their in vivo functions in skin immunity and tolerance could not…”
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Prostaglandin E2-EP4 signaling initiates skin immune responses by promoting migration and maturation of Langerhans cells
Published in Nature medicine (01-06-2003)“…Antigen-specific immune responses in the skin are initiated by antigen uptake into Langerhans cells and the subsequent migration of these cells to draining…”
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The CD8+ dendritic cell subset selectively endocytoses dying cells in culture and in vivo
Published in The Journal of experimental medicine (20-05-2002)“…Dendritic cells (DCs) are able in tissue culture to phagocytose and present antigens derived from infected, malignant, and allogeneic cells. Here we show…”
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Efficient capture of Candida albicans and zymosan by SIGNR1 augments TLR2-dependent TNF-α production
Published in International immunology (01-02-2012)“…SIGNR1, a mouse C-type lectin, binds various pathogens, including Candida albicans. In this study, we explore the impact of SIGNR1 in the recognition of C…”
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Hyperplastic gastric tumors induced by activated macrophages in COX-2/mPGES-1 transgenic mice
Published in The EMBO journal (07-04-2004)“…Cyclooxygenase‐2 (COX‐2), the rate‐limiting enzyme for prostanoid biosynthesis, plays a key role in gastrointestinal carcinogenesis. Among various prostanoids,…”
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Immune tolerance after delivery of dying cells to dendritic cells in situ
Published in The Journal of experimental medicine (21-10-2002)“…Peripheral immune tolerance is believed to be induced by the processing and presentation of self-tissues that die during physiologic tissue turnover. To…”
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Absence of DCIR1 reduces the mortality rate of endotoxemic hepatitis in mice
Published in European journal of immunology (01-04-2017)“…Dendritic cell immunoreceptor (DCIR) is a C‐type lectin with an immunoreceptor tyrosine‐based inhibitory motif (ITIM). Mice lacking DCIR1 (Dcir1−/− mice) show…”
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Pivotal role of CXCR3 in melanoma cell metastasis to lymph nodes
Published in Cancer research (Chicago, Ill.) (01-06-2004)“…Chemokines and their receptors play key roles in leukocyte trafficking and are also implicated in cancer metastasis to specific organs. Here we show that mouse…”
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Dendritic Cell Function in Vivo during the Steady State: A Role in Peripheral Tolerance
Published in Annals of the New York Academy of Sciences (01-04-2003)“…: The avoidance of autoimmunity requires mechanisms to actively silence or tolerize self reactive T cells in the periphery. During infection, dendritic cells…”
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Particle size of latex beads dictates IL-1β production mechanism
Published in PloS one (09-07-2013)“…Macrophages (Mϕ) are well documented to produce IL-1β through various signaling pathways in response to small particles such as silica, asbestos and urea…”
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tetraspanin CD9 mediates lateral association of MHC class II molecules on the dendritic cell surface
Published in Proceedings of the National Academy of Sciences - PNAS (02-01-2007)“…We have found that MHC class II (MHC II) molecules exhibit a distinctive organization on the dendritic cell (DC) plasma membrane. Both in DC lysates and on the…”
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Human CD1c+ Myeloid Dendritic Cells Acquire a High Level of Retinoic Acid–Producing Capacity in Response to Vitamin D3
Published in The Journal of immunology (1950) (15-09-2013)“…Abstract All-trans-retinoic acid (RA) plays a critical role in maintaining immune homeostasis. Mouse intestinal CD103+ dendritic cells (DCs) produce a high…”
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Correction: HTLV-1 bZIP Factor Enhances T-cell Proliferation by Impeding the Suppressive Signaling of Co-inhibitory Receptors
Published in PLoS pathogens (01-02-2017)“…[This corrects the article DOI: 10.1371/journal.ppat.1006120.]…”
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Effective Expansion of Alloantigen-Specific Foxp3⁺ CD25⁺ CD4⁺ Regulatory T Cells by Dendritic Cells during the Mixed Leukocyte Reaction
Published in Proceedings of the National Academy of Sciences - PNAS (21-02-2006)“…Thymic-derived CD25⁺ CD4⁺ T regulatory cells (Tregs) suppress immune responses, including transplantation. Here we evaluated the ability of dendritic cells…”
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Difference in Fine Specificity to Polysaccharides of Candida albicans Mannoprotein between Mouse SIGNR1 and Human DC-SIGN
Published in Infection and Immunity (01-05-2012)“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Crucial functions of the Rap1 effector molecule RAPL in lymphocyte and dendritic cell trafficking
Published in Nature immunology (01-10-2004)“…Immunosurveillance requires the coordinated regulation of chemokines and adhesion molecules to guide immune cell migration. However, the critical molecule for…”
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Identification of a novel type 2 innate immunocyte with the ability to enhance IgE production
Published in International immunology (01-06-2013)“…Fas (CD95), a member of the tumor necrosis factor receptor superfamily, mediates apoptosis-inducing signals in its expressing cells, especially in…”
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