Search Results - "Inaba, Hiroshi"

Development of Dynamic Bionanostructures Based on Peptides: Molecular Encapsulation Inside Microtubules and Light-induced Propulsion of Microspheres by Inaba, Hiroshi

“…This highlight review summarizes our latest research on the construction of dynamic bionanostructures through peptide design. In the first topic, we developed…”
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Modulation of Microtubule Properties and Functions by Encapsulation of Nanomaterials Using a Tau-Derived Peptide by Inaba, Hiroshi, Matsuura, Kazunori

“…Microtubules (MTs) are hollow cytoskeletons with typically 15 nm inner diameter, which are crucial for various cellular activities including structural…”
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Encapsulation of Nanomaterials Inside Microtubules by Using a Tau-Derived Peptide by Inaba, Hiroshi, Matsuura, Kazunori

“…Microtubules (MTs) are tubular cytoskeletons, which are used for the various applications such as active matters and therapeutic targets. Although modification…”
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A supramolecular system mimicking the infection process of an enveloped virus through membrane fusion by Furukawa, Hiroto, Kimura, Yuuna, Inaba, Hiroshi, Matsuura, Kazunori

“…Membrane fusion is an essential step for the entry of enveloped viruses, such as human immunodeficiency virus and influenza virus, into the host cell, often…”
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Properties and Classification of Diamond-Like Carbon Films by Ohtake, Naoto, Hiratsuka, Masanori, Kanda, Kazuhiro, Akasaka, Hiroki, Tsujioka, Masanori, Hirakuri, Kenji, Hirata, Atsushi, Ohana, Tsuguyori, Inaba, Hiroshi, Kano, Makoto, Saitoh, Hidetoshi

“…Diamond-like carbon (DLC) films have been extensively applied in industries owing to their excellent characteristics such as high hardness. In particular,…”
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Alkyl anchor-modified artificial viral capsid budding outside-to-inside and inside-to-outside giant vesicles by Matsuura, Kazunori, Hirahara, Miu, Sakamoto, Kentarou, Inaba, Hiroshi

“…The budding of human immunodeficiency virus from an infected host cell is induced by the modification of structural proteins bearing long-chain fatty acids,…”
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Construction of Ribonuclease-Decorated Artificial Virus-like Capsid by Peptide Self-assembly by Matsuura, Kazunori, Ota, Junpei, Fujita, Seiya, Shiomi, Yuriko, Inaba, Hiroshi

“…Artificial virus-like capsids decorated with ribonuclease S (RNase S) on their exterior were constructed by the self-assembly of β-annulus-S-peptide and the…”
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Fluorescence Correlation Spectroscopy Analysis of Effect of Molecular Crowding on Self-Assembly of β -Annulus Peptide into Artificial Viral Capsid by Kobayashi, Risako, Inaba, Hiroshi, Matsuura, Kazunori

“…Recent progress in the design of self-assembling peptides has enabled the construction of peptide-based viral capsids. Previously, we demonstrated that 24-mer…”
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Intracellular delivery and photothermal therapeutic effects of polyhistidine peptide-modified gold nanoparticles by Hori, Kosuke, Higashida, Shinichi, Osaki, Tomohiro, Kawano, Tsuyoshi, Inaba, Hiroshi, Matsuura, Kazunori, Iwasaki, Takashi

“…Gold nanoparticles (AuNPs) are widely used as an agent in photothermal therapy (PTT) against various cancers. However, a drug delivery system (DDS) is required…”
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Construction of Artificial Viral Capsids Encapsulating Short DNAs via Disulfide Bonds and Controlled Release of DNAs by Reduction by Nakamura, Yoko, Inaba, Hiroshi, Matsuura, Kazunori

“…To construct an artificial viral capsid encapsulated short single-stranded DNA, a β-annulus peptide conjugated with ssDNA through a disulfide bond at the…”
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Magnetic Force-Induced Alignment of Microtubules by Encapsulation of CoPt Nanoparticles Using a Tau-Derived Peptide by Inaba, Hiroshi, Yamada, Mayuki, Rashid, Mst. Rubaya, Kabir, Arif Md. Rashedul, Kakugo, Akira, Sada, Kazuki, Matsuura, Kazunori

“…Construction of magnetotactic materials is a significant challenge in nanotechnology applications such as nanodevices and nanotransportation. Artificial…”
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Immunological Evaluation of Co‐Assembling a Lipidated Peptide Antigen and Lipophilic Adjuvants: Self‐Adjuvanting Anti‐Breast‐Cancer Vaccine Candidates by Aiga, Taku, Manabe, Yoshiyuki, Ito, Keita, Chang, Tsung‐Che, Kabayama, Kazuya, Ohshima, Shino, Kametani, Yoshie, Miura, Ayane, Furukawa, Hiroto, Inaba, Hiroshi, Matsuura, Kazunori, Fukase, Koichi

“…Co‐assembling vaccines composed of a lipidated HER2‐derived antigenic CH401 peptide and either a lipophilic adjuvant, Pam3CSK4, α‐GalCer, or lipid A 506, were…”
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Binding of Tau-derived peptide-fused GFP to plant microtubules in Arabidopsis thaliana by Inaba, Hiroshi, Oikawa, Kazusato, Ishikawa, Kazuya, Kodama, Yutaka, Matsuura, Kazunori, Numata, Keiji

“…Studies on how exogenous molecules modulate properties of plant microtubules, such as their stability, structure, and dynamics, are important for understanding…”
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Prolonged α-thrombin-related activation and delayed active protein C-associated degradation confer mild phenotype in a patient with severe hemophilia A with F8 p.H118R by Miyashita, Ryui, Shinozawa, Keiko, Inaba, Hiroshi, Amano, Kagehiro, Kinai, Ei

“…In hemophilia A, bleeding mostly correlates with factor VIII activity (FVIII:C), although some patients show discrepancy in bleeding severity and FVIII:C. We…”
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Mechanistic Studies for the Rational Design of Multivalent Glycodendrimers by Manabe, Yoshiyuki, Tsutsui, Masato, Hirao, Kohtaro, Kobayashi, Risako, Inaba, Hiroshi, Matsuura, Kazunori, Yoshidome, Daisuke, Kabayama, Kazuya, Fukase, Koichi

“…We have synthesized B‐antigen‐displaying dendrimers (16‐mers) with different sizes and evaluated their affinity to their IgM antibody in order to investigate…”
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Molecular Encapsulation Inside Microtubules Based on Tau‐Derived Peptides by Inaba, Hiroshi, Yamamoto, Takahisa, Kabir, Arif Md. Rashedul, Kakugo, Akira, Sada, Kazuki, Matsuura, Kazunori

“…Microtubules are cytoskeletal filaments that serve as attractive scaffolds for developing nanomaterials and nanodevices because of their unique structural…”
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Design of biomaterials for intracellular delivery of carbon monoxide by Inaba, Hiroshi, Fujita, Kenta, Ueno, Takafumi

“…Carbon monoxide (CO) is recognized as one of the most important gas signaling molecules involved in governing various therapeutic responses. Intracellular…”
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In vitro validation of chromogenic substrate assay for evaluation of surrogate FVIII-activity of emicizumab by Yamaguchi, Tomoko, Shinozawa, Keiko, Nagatoishi, Satoru, Mitsuhashi, Ayano, Bingo, Masato, Inaba, Hiroshi, Amano, Kagehiro, Tsumoto, Kohei, Kinai, Ei

“…[Introduction] Emicizumab, a bispecific antibody mimicking activated factor VIII (FVIII), is increasingly used in prophylaxis against bleeding in hemophilia A…”
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Structural Changes of Microtubules by Encapsulation of Gold Nanoparticles Using a Tau-derived Peptide by Inaba, Hiroshi, Kabir, Arif Md Rashedul, Kakugo, Akira, Sada, Kazuki, Matsuura, Kazunori

“…This study encapsulated gold nanoparticles (AuNPs) in microtubules (MTs) by conjugating a Tau-derived peptide (TP) and evaluated the effects on MTs. Among the…”
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Dramatic morphological changes in liposomes induced by peptide nanofibers reversibly polymerized and depolymerized by the photoisomerization of spiropyran by Liang, Yingbing, Ogawa, Shigesaburo, Inaba, Hiroshi, Matsuura, Kazunori

“…Cytoskeletons such as microtubules and actin filaments are natural protein assemblies, which dynamically control cellular morphology by reversible…”
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