Search Results - "In Moon, Byung"
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BRCA1 / BRCA2 Pathogenic Variant Breast Cancer: Treatment and Prevention Strategies
Published in Annals of laboratory medicine (01-03-2020)“…Hereditary breast cancer is known for its strong tendency of inheritance. Most hereditary breast cancers are related to / pathogenic variants. The lifelong…”
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Selenium inhibits growth of trastuzumab-resistant human breast cancer cells via downregulation of Akt and beclin-1
Published in PloS one (15-09-2021)“…The response rate to treatment with trastuzumab (Tz), a recombinant humanized anti-HER2 monoclonal antibody, is only 12-34% despite demonstrated effectiveness…”
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Increased risk of postoperative complications after total thyroidectomy with Graves' disease
Published in Head & neck (01-02-2019)“…Background The effect of Graves' disease on the risk of postoperative complications in patients undergoing total thyroidectomy is unclear. Methods The…”
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Prognosis of papillary thyroid cancer in patients with Graves' disease: a propensity score-matched analysis
Published in World journal of surgical oncology (13-10-2020)“…Patients with Graves' disease (GD) are at a 2.5 times higher risk of developing thyroid cancer than the general population. Previous studies reported…”
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Prediction of breast cancer using blood microbiome and identification of foods for breast cancer prevention
Published in Scientific reports (29-03-2023)“…The incidence of breast cancer (BC) is increasing in South Korea, and diet is closely related to the high prevalence of BC. The microbiome directly reflects…”
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Efficacy of a clinical pathway for patients with thyroid cancer
Published in Head & neck (01-09-2018)“…Background Clinical pathways have been proposed as a way to improve organizational efficiency and maximize patient outcomes. However, little is known as to…”
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Syndecan-2 enhances E-cadherin shedding and fibroblast-like morphological changes by inducing MMP-7 expression in colon cancer cells
Published in Biochemical and biophysical research communications (12-08-2016)“…E-cadherin plays a mechanical role in mediating cell-cell interactions and maintaining epithelial tissue integrity, and the loss of E-cadherin function has…”
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Use of CA15‑3 for screening breast cancer: An antibody‑lectin sandwich assay for detecting glycosylation of CA15‑3 in sera
Published in Oncology reports (01-07-2018)“…Elevated serum CA15‑3 assessed by enzyme‑linked immunosorbent assay (ELISA) has been considered a diagnostic marker of breast cancer. However, accumulating…”
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Feasibility of Classification of Triple Negative Breast Cancer by Immunohistochemical Surrogate Markers
Published in Clinical breast cancer (01-10-2018)“…Using the 7 immunohistochemical surrogate markers, we tried to classify 200 TNBCs into 4 molecular subtypes; luminal androgen receptor, mesenchymal, basal-like…”
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Functional Modulation of Regulatory T Cells by IL-2
Published in PloS one (03-11-2015)“…The suppressive function of regulatory T cells (Tregs) is critical to the maintenance of immune homeostasis in vivo and yet, the specific identification of…”
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Reinterpretation of BRCA1 and BRCA2 variants of uncertain significance in patients with hereditary breast/ovarian cancer using the ACMG/AMP 2015 guidelines
Published in Breast cancer (Tokyo, Japan) (01-07-2019)“…Background Although BRCA1 or BRCA2 ( BRCA1 / 2 ) genetic testing plays an important role in determining treatment modalities in patients with hereditary breast…”
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Reactive oxygen species prevent imiquimod-induced psoriatic dermatitis through enhancing regulatory T cell function
Published in PloS one (07-03-2014)“…Psoriasis is a chronic inflammatory skin disease resulting from immune dysregulation. Regulatory T cells (Tregs) are important in the prevention of psoriasis…”
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Evaluation of Group Genetic Counseling Sessions via a Metaverse-based Application
Published in Annals of laboratory medicine (01-01-2024)“…BackgroundGroup genetic counseling has been implemented to meet growing demand. A metaverse platform, in which a society is built and activities are carried…”
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The effect of adjuvant chemotherapy on survival in Korean patients with node negative T1c, triple negative breast cancer
Published in PloS one (16-05-2018)“…The present study investigated the prognostic role of adjuvant systemic chemotherapy in patients with node negative, T1c triple negative breast cancer (TNBC)…”
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A prospective randomized controlled trial to determine the safety and efficacy of extracorporeal shock waves therapy for primary prevention of subclinical cardiotoxicity in breast cancer patients without a cardiovascular risk treated with doxorubicin
Published in Frontiers in cardiovascular medicine (07-02-2024)“…Doxorubicin is a highly effective anti-cancer drug that causes left ventricular (LV) dysfunction and induces late-onset cardiomyopathy. However, an effective…”
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Prognostic value of human apurinic/apyrimidinic endonuclease 1 (APE1) expression in breast cancer
Published in PloS one (10-06-2014)“…Human apurinic/apyrimidinic endonuclease 1 (APE1) is an essential protein for DNA base excision repair (BER) and redox regulation. The ability of cancer cells…”
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Expression patterns of GATA3 and the androgen receptor are strongly correlated in patients with triple-negative breast cancer
Published in Human pathology (01-09-2016)“…GATA3 is a diagnostically useful immunohistochemical marker of breast cancer. Because of its strong association with ER expression, GATA3 has markedly reduced…”
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Attenuation of experimental colitis in glutathione peroxidase 1 and catalase double knockout mice through enhancing regulatory T cell function
Published in PloS one (01-04-2014)“…Reactive oxygen species (ROS) have been implicated in the progression of inflammatory diseases including inflammatory bowel diseases (IBD). Meanwhile, several…”
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Exogenous C2 Ceramide Suppresses Matrix Metalloproteinase Gene Expression by Inhibiting ROS Production and MAPK Signaling Pathways in PMA-Stimulated Human Astroglioma Cells
Published in International journal of molecular sciences (31-03-2016)“…Matrix metalloproteinases (MMPs) are a family of zinc-dependent endopeptidases, which play a pivotal role in invasion, migration, and angiogenesis of glioma…”
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A nationwide, multicenter retrospective study on the effectiveness and safety of eribulin in Korean breast cancer patients (REMARK)
Published in Breast (Edinburgh) (01-12-2020)“…Approval of eribulin for metastatic breast cancer was based on data primarily from Western patients, and there is a paucity of data on the effectiveness and…”
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