Search Results - "Inácio, Ana R."
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1
Posteromedial thalamic nucleus activity significantly contributes to perceptual discrimination
Published in PLoS biology (28-11-2022)“…Higher-order sensory thalamic nuclei are densely connected with multiple cortical and subcortical areas, yet the role of these nuclei remains elusive. The…”
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2
GABAA receptor dephosphorylation followed by internalization is coupled to neuronal death in in vitro ischemia
Published in Neurobiology of disease (01-05-2014)“…Abstract Cerebral ischemia is characterized by an early disruption of GABAergic neurotransmission contributing to an imbalance of the excitatory/inhibitory…”
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3
Effects of the sigma-1 receptor agonist 1-(3,4-dimethoxyphenethyl)-4-(3-phenylpropyl)-piperazine dihydro-chloride on inflammation after stroke
Published in PloS one (18-09-2012)“…Activation of the sigma-1 receptor (Sig-1R) improves functional recovery in models of experimental stroke and is known to modulate microglia function. The…”
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4
Endogenous IFN-β signaling exerts anti-inflammatory actions in experimentally induced focal cerebral ischemia
Published in Journal of neuroinflammation (18-11-2015)“…Interferon (IFN)-β exerts anti-inflammatory effects, coupled to remarkable neurological improvements in multiple sclerosis, a neuroinflammatory condition of…”
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5
Excitotoxicity downregulates TrkB.FL signaling and upregulates the neuroprotective truncated TrkB receptors in cultured hippocampal and striatal neurons
Published in The Journal of neuroscience (28-03-2012)“…Brain-derived neurotrophic factor (BDNF) plays an important role in neuronal survival through activation of TrkB receptors. The trkB gene encodes a full-length…”
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6
Cleavage of the vesicular GABA transporter under excitotoxic conditions is followed by accumulation of the truncated transporter in nonsynaptic sites
Published in The Journal of neuroscience (23-03-2011)“…GABA is the major inhibitory neurotransmitter in the CNS and changes in GABAergic neurotransmission affect the overall activity of neuronal networks. The…”
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7
Cleavage of the vesicular glutamate transporters under excitotoxic conditions
Published in Neurobiology of disease (01-12-2011)“…Abstract Glutamate is loaded into synaptic vesicles by vesicular glutamate transporters (VGLUTs), and alterations in the transporters expression directly…”
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8
Sensory feedback synchronizes motor and sensory neuronal networks in the neonatal rat spinal cord
Published in Nature communications (07-10-2016)“…Early stages of sensorimotor system development in mammals are characterized by the occurrence of spontaneous movements. Whether and how these movements…”
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9
Macrophage migration inhibitory factor promotes cell death and aggravates neurologic deficits after experimental stroke
Published in Journal of cerebral blood flow and metabolism (01-04-2011)“…Multiple mechanisms contribute to tissue demise and functional recovery after stroke. We studied the involvement of macrophage migration inhibitory factor…”
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10
Enriched environment downregulates macrophage migration inhibitory factor and increases parvalbumin in the brain following experimental stroke
Published in Neurobiology of disease (01-02-2011)“…Abstract Housing rodents in an enriched environment (EE) following experimental stroke enhances neurological recovery. Understanding the underlying neural cues…”
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11
Lack of macrophage migration inhibitory factor in mice does not affect hallmarks of the inflammatory/immune response during the first week after stroke
Published in Journal of neuroinflammation (29-06-2011)“…Macrophage migration inhibitory factor (MIF) has been proposed to play a detrimental role in stroke. We recently showed that MIF promotes neuronal death and…”
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12
Effects of chronic Clozapine administration on apolipoprotein D levels and on functional recovery following experimental stroke
Published in Brain research (19-03-2010)“…Abstract Elevated brain levels of apolipoprotein D (ApoD) correlate with improved neurological recovery after experimental stroke. Hence, a pharmacological…”
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13
Isoflurane suppresses early cortical activity
Published in Annals of clinical and translational neurology (01-01-2014)“…Objective Isoflurane and other volatile anesthetics are widely used in children to induce deep and reversible coma, but they may also exert neurotoxic actions…”
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14
Effects of the Sigma-1 Receptor Agonist 1
Published in PloS one (18-09-2012)“…Activation of the sigma-1 receptor (Sig-1R) improves functional recovery in models of experimental stroke and is known to modulate microglia function. The…”
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15
Effects of the Sigma-1 Receptor Agonist 1--Piperazine Dihydro-Chloride on Inflammation after Stroke
Published in PloS one (18-09-2012)“…Activation of the sigma-1 receptor (Sig-1R) improves functional recovery in models of experimental stroke and is known to modulate microglia function. The…”
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Journal Article -
16
Endogenous IFN-[beta] signaling exerts anti-inflammatory actions in experimentally induced focal cerebral ischemia
Published in Journal of neuroinflammation (18-11-2015)“…Background Interferon (IFN)-[beta] exerts anti-inflammatory effects, coupled to remarkable neurological improvements in multiple sclerosis, a neuroinflammatory…”
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Journal Article -
17
GABA(A) receptor dephosphorylation followed by internalization is coupled to neuronal death in in vitro ischemia
Published in Neurobiology of disease (01-05-2014)“…Cerebral ischemia is characterized by an early disruption of GABAergic neurotransmission contributing to an imbalance of the excitatory/inhibitory equilibrium…”
Get full text
Journal Article -
18
GABA sub(A) receptor dephosphorylation followed by internalization is coupled to neuronal death in in vitro ischemia
Published in Neurobiology of disease (01-05-2014)“…Cerebral ischemia is characterized by an early disruption of GABAergic neurotransmission contributing to an imbalance of the excitatory/inhibitory equilibrium…”
Get full text
Journal Article