Search Results - "In, M"
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1
The ginger component 6-shogaol prevents TNF-α-induced barrier loss via inhibition of PI3K/Akt and NF-κB signaling
Published in Molecular nutrition & food research (01-12-2016)“…Scope Anti‐inflammatory properties of the ginger‐derived pungent component 6‐shogaol (6‐SG) have been studied intensively in recent years. Purpose of this…”
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2
Tight junction strand formation by claudin‐10 isoforms and claudin‐10a/‐10b chimeras
Published in Annals of the New York Academy of Sciences (01-10-2017)“…Claudins are integral components of tight junctions (TJs) in epithelia and endothelia. When expressed in cell lines devoid of TJs, claudins are able to form…”
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3
Reversible opening of the blood-brain barrier by claudin-5-binding variants of Clostridium perfringens enterotoxin's claudin-binding domain
Published in Biomaterials (01-04-2018)“…The blood-brain barrier (BBB) prevents entry of neurotoxic substances but also that of drugs into the brain. Here, the paracellular barrier is formed by tight…”
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4
Improved cell line IPEC-J2, characterized as a model for porcine jejunal epithelium
Published in PloS one (15-11-2013)“…Cell lines matching the source epithelium are indispensable for investigating porcine intestinal transport and barrier properties on a subcellular or molecular…”
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5
Charge-selective claudin channels
Published in Annals of the New York Academy of Sciences (01-06-2012)“…Claudins are the main determinants of barrier properties of the tight junction. Many claudins have been shown to act by tightening the paracellular pathway,…”
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6
Tissue engineering with gellan gum
Published in Biomaterials science (16-08-2016)“…Engineering complex tissues for research and clinical applications relies on high-performance biomaterials that are amenable to biofabrication, maintain…”
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7
Differential effects and success stories of distance education in Covid-19 lockdowns on the development of reading comprehension in primary schools
Published in Reading & writing (01-02-2023)“…In the current study, the development in reading comprehension performance of students in lower-SES versus higher-SES schools during and after school closures…”
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8
Predicting vasovagal reactions to needles with anticipatory facial temperature profiles
Published in Scientific reports (14-06-2023)“…Around one-third of adults are scared of needles, which can result in adverse emotional and physical responses such as dizziness and fainting (e.g. vasovagal…”
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9
Experimental study of the potential hazards of surgical smoke from powered instruments
Published in British journal of surgery (01-11-2015)“…Background Many surgical instruments have been replaced with powered devices in open gastrointestinal and laparoscopic surgery. The production of smoke as a…”
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10
Update of the Pompe variant database for the prediction of clinical phenotypes: Novel disease‐associated variants, common sequence variants, and results from newborn screening
Published in Human mutation (01-02-2021)“…Pompe disease is an inherited disorder caused by disease‐associated variants in the acid α‐glucosidase gene (GAA). The Pompe disease GAA variant database…”
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11
Goal Management Training in Adults With ADHD: An Intervention Study
Published in Journal of attention disorders (01-11-2017)“…Objective: This article describes a controlled, neuropsychological intervention study in adult ADHD. We examined whether adults with ADHD would benefit from a…”
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12
Impaired Intestinal Permeability of Tricellular Tight Junctions in Patients with Irritable Bowel Syndrome with Mixed Bowel Habits (IBS-M)
Published in Cells (Basel, Switzerland) (05-01-2023)“…The underlying pathophysiology of irritable bowel syndrome (IBS) is still unclear. Our aim was to investigate the pathophysiological mechanisms of diarrhea,…”
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13
α-Haemolysin of Escherichia coli in IBD: a potentiator of inflammatory activity in the colon
Published in Gut (01-12-2014)“…α-Haemolysin (HlyA) influences host cell ionic homeostasis and causes concentration-dependent cell lysis. As a consequence, HlyA-producing Escherichia coli is…”
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14
Body adiposity predictors of Vitamin D status in nondialyzed patients with chronic kidney disease: A cross-sectional analysis in a tropical climate city
Published in Nutrition (Burbank, Los Angeles County, Calif.) (01-01-2017)“…Abstract The association of Vitamin D status with high body adiposity is poorly investigated in chronic kidney disease (CKD) population. The aim of the present…”
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15
Reconnaissance of Allostery via the Restoration of Native p53 DNA-Binding Domain Dynamics in Y220C Mutant p53 Tumor Suppressor Protein
Published in ACS omega (07-05-2024)“…Allosteric regulation of protein dynamics infers a long-range deliberate propagation of information via micro- and macroscale interactions. The Y220C…”
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16
Epithelial Barrier Dysfunction in Diarrhea-Predominant Irritable Bowel Syndrome (IBS-D) via Downregulation of Claudin-1
Published in Cells (Basel, Switzerland) (01-12-2023)“…In patients with diarrhea-predominant irritable bowel syndrome (IBS-D), the diarrheal mechanisms are largely unknown, and they were examined in this study on…”
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17
Higher prevalence of dupilumab‐induced ocular adverse events in atopic dermatitis compared to asthma: A daily practice analysis
Published in Clinical and translational allergy (01-08-2024)“…Background Dupilumab has been shown to be an effective treatment in moderate‐to‐severe atopic dermatitis (AD) and severe asthma (SA). However, comparative…”
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Insights into Rational Design of a New Class of Allosteric Effectors with Molecular Dynamics Markov State Models and Network Theory
Published in ACS omega (25-01-2022)“…The development of drugs to restore protein function has been a major advance facilitated by molecular medicine. Allosteric regulation, a phenomenon widely…”
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Case-control study of patient characteristics, knowledge of the COVID-19 disease, risk behaviour and mental state in patients visiting an emergency room with COVID-19 symptoms in the Netherlands
Published in PloS one (28-04-2021)“…Coronavirus disease 2019 is a serious respiratory virus pandemic. Patient characteristics, knowledge of the COVID-19 disease, risk behaviour and mental state…”
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The effect of Mindfulness-Based Stress Reduction on wound healing: a preliminary study
Published in Journal of behavioral medicine (01-06-2018)“…Psychological factors have been shown to influence the process of wound healing. This study examined the effect of Mindfulness-Based Stress Reduction (MBSR) on…”
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