Search Results - "Imrichova, Terezie"
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Interferon‐regulated suprabasin is essential for stress‐induced stem‐like cell conversion and therapy resistance of human malignancies
Published in Molecular oncology (01-07-2019)“…Radiation and chemotherapy represent standard‐of‐care cancer treatments. However, most patients eventually experience tumour recurrence, treatment failure and…”
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Dynamic PML protein nucleolar associations with persistent DNA damage lesions in response to nucleolar stress and senescence-inducing stimuli
Published in Aging (Albany, NY.) (07-09-2019)“…Diverse stress insults trigger interactions of PML with nucleolus, however, the function of these PML nucleolar associations (PNAs) remains unclear. Here we…”
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Induction, regulation and roles of neural adhesion molecule L1CAM in cellular senescence
Published in Aging (Albany, NY.) (28-03-2018)“…Aging involves tissue accumulation of senescent cells (SC) whose elimination through senolytic approaches may evoke organismal rejuvenation. SC also contribute…”
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Tumor growth accelerated by chemotherapy-induced senescent cells is suppressed by treatment with IL-12 producing cellular vaccines
Published in Oncotarget (23-08-2016)“…Standard-of-care chemo- or radio-therapy can induce, besides tumor cell death, also tumor cell senescence. While senescence is considered to be a principal…”
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