Search Results - "Imoto, Kyoko"

Ocular Manifestations of Xeroderma Pigmentosum by Brooks, Brian P., MD, PhD, Thompson, Amy H., PhD, Bishop, Rachel J., MD, Clayton, Janine A., MD, Chan, Chi-Chao, MD, Tsilou, Ekaterini T., MD, Zein, Wadih M., MD, Tamura, Deborah, RN, MS, Khan, Sikandar G., PhD, Ueda, Takahiro, PhD, Boyle, Jennifer, PhD, Oh, Kyu-Seon, PhD, Imoto, Kyoko, PhD, Inui, Hiroki, PhD, Moriwaki, Shin-Ichi, PhD, Emmert, Steffen, MD, Iliff, Nicholas T., MD, Bradford, Porcia, MD, DiGiovanna, John J., MD, Kraemer, Kenneth H., MD

“…Objective Xeroderma pigmentosum (XP) is a rare autosomal recessive disease caused by mutations in DNA repair genes. Clinical manifestations of XP include mild…”
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Epidermal growth factor receptor inhibitors selectively inhibit the expressions of human β-defensins induced by Staphylococcus epidermidis by Park, Kio, Ommori, Rie, Imoto, Kyoko, Asada, Hideo

“…Highlights • EGFRIs did not suppress the expressions of hBD1 and 3 induced by S. aureus. • In contrast, EGFRIs suppressed the expressions of hBD2 and 3 induced…”
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VZV skin-test reaction, but not antibody, is an important predictive factor for postherpetic neuralgia by Imoto, Kyoko, Okazaki, Aiko, Onishi, Fumitake, Miyazaki, Yoshiyuki, Okeda, Masayuki, Yano, Shuichiro, Takao, Yukiko, Gomi, Yasuyuki, Ishikawa, Toyokazu, Okuno, Yoshinobu, Mori, Yasuko, Iso, Hiroyasu, Yamanishi, Koichi, Asada, Hideo

“…Highlights • A large-scale prospective cohort study on the postherpetic neuralgia was conducted. • A weak VZV skin-test reaction was an important predictive…”
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Ancient origin of a Japanese xeroderma pigmentosum founder mutation by Imoto, Kyoko, Nadem, Carine, Moriwaki, Shin-Ichi, Nishigori, Chikako, Oh, Kyu-Seon, Khan, Sikandar G, Goldstein, Alisa M, Kraemer, Kenneth H

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DNA single-strand break repair is impaired in aprataxin-related ataxia by Hirano, Makito, Yamamoto, Aya, Mori, Toshio, Lan, Li, Iwamoto, Taka-Aki, Aoki, Masashi, Shimada, Keiji, Furiya, Yoshiko, Kariya, Shingo, Asai, Hirohide, Yasui, Akira, Nishiwaki, Tomohisa, Imoto, Kyoko, Kobayashi, Nobuhiko, Kiriyama, Takao, Nagata, Tetsuya, Konishi, Noboru, Itoyama, Yasuto, Ueno, Satoshi

“…Objective Early‐onset ataxia with ocular motor apraxia and hypoalbuminemia (EAOH)/ataxia with oculomotor apraxia type 1 (AOA1) is an autosomal recessive form…”
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Structural and Molecular Hair Abnormalities in Trichothiodystrophy by Liang, Christine, Morris, Andrea, Schlücker, Sebastian, Imoto, Kyoko, Price, Vera H., Menefee, Emory, Wincovitch, Stephen M., Levin, Ira W., Tamura, Deborah, Strehle, Katrin R., Kraemer, Kenneth H., DiGiovanna, John J.

“…We examined hair from 15 patients with trichothiodystrophy (TTD), a rare inherited disorder with brittle, cystine-deficient hair. They had a wide variety of…”
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In Situ Visualization of Ultraviolet-Light-Induced DNA Damage Repair in Locally Irradiated Human Fibroblasts by Katsumi, Sachiko, Kobayashi, Nobuhiko, Imoto, Kyoko, Nakagawa, Akemi, Yamashina, Yukio, Muramatsu, Tsutomu, Shirai, Toshihiko, Miyagawa, Sachiko, Sugiura, Shigeki, Hanaoka, Fumio, Matsunaga, Tsukasa, Nikaido, Osamu, Mori, Toshio

“…We have developed a novel method that uses a microfilter mask to produce ultraviolet-induced DNA lesions in localized areas of the cell nucleus. This technique…”
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Influence of XPB helicase on recruitment and redistribution of nucleotide excision repair proteins at sites of UV-induced DNA damage by Oh, Kyu-Seon, Imoto, Kyoko, Boyle, Jennifer, Khan, Sikandar G., Kraemer, Kenneth H.

“…The XPB DNA helicase, a subunit of the basal transcription factor TFIIH, is also involved in nucleotide excision repair (NER). We examined recruitment of NER…”
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Trichothiodystrophy Fibroblasts Are Deficient in the Repair of Ultraviolet-Induced Cyclobutane Pyrimidine Dimers and (6–4)Photoproducts by Nishiwaki, Yoko, Kobayashi, Nobuhiko, Imoto, Kyoko, Iwamoto, Taka-aki, Yamamoto, Aya, Katsumi, Sachiko, Shirai, Toshihiko, Sugiura, Shigeki, Nakamura, Yu, Sarasin, Alain, Miyagawa, Sachiko, Mori, Toshio

“…A photosensitive form of trichothiodystrophy (TTD) results from mutations in the same XPD gene as the DNA-repair-deficient genetic disorder xeroderma…”
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A Novel Complex Insertion/Deletion Mutation in the XPC DNA Repair Gene Leads to Skin Cancer in an Iraqi Family by Emmert, Steffen, Wetzig, Tino, Imoto, Kyoko, Khan, Sikandar G., Oh, Kyu-Seon, Laspe, Petra, Zachmann, Karolin, Simon, Jan C., Kraemer, Kenneth H.

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In situ detection of acetylaminofluorene–DNA adducts in human cells using monoclonal antibodies by Iwamoto, Taka-aki, Kobayashi, Nobuhiko, Imoto, Kyoko, Yamamoto, Aya, Nakamura, Yu, Yamauchi, Yukika, Okumura, Hiromi, Tanaka, Akiko, Hanaoka, Fumio, Shibutani, Shinya, Miyagawa, Sachiko, Mori, Toshio

“…The present study was performed to generate monoclonal antibodies capable of detecting N-acetoxy-2-acetylaminofluorene (NA-AAF)-derived DNA adducts in human…”
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Cancer and neurologic degeneration in xeroderma pigmentosum: long term follow-up characterises the role of DNA repair by Bradford, Porcia T, Goldstein, Alisa M, Tamura, Deborah, Khan, Sikandar G, Ueda, Takahiro, Boyle, Jennifer, Oh, Kyu-Seon, Imoto, Kyoko, Inui, Hiroki, Moriwaki, Shin-Ichi, Emmert, Steffen, Pike, Kristen M, Raziuddin, Arati, Plona, Teri M, DiGiovanna, John J, Tucker, Margaret A, Kraemer, Kenneth H

“…The frequency of cancer, neurologic degeneration and mortality in xeroderma pigmentosum (XP) patients with defective DNA repair was determined in a four decade…”
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Epidermal growth factor receptor inhibitors selectively inhibit the expression of human β-defensins induced by Staphylococci by Ommori, Rie, Park, Kio, Imoto, Kyoko, Asada, Hideo

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The Total Amount of DNA Damage Determines Ultraviolet-radiation-induced Cytotoxicity After Uniformor Localized Irradiation of Human Cells by Imoto, Kyoko, Kobayashi, Nobuhiko, Katsumi, Sachiko, Nishiwaki, Yoko, Iwamoto, Taka-aki, Yamamoto, Aya, Yamashina, Yukio, Shirai, Toshihiko, Miyagawa, Sachiko, Dohi, Yoshiko, Sugiura, Shigeki, Mori, Toshio

“…We have recently developed a micropore ultraviolet irradiation technique. An isopore membrane filter with 3 μm diameter pores shields ultraviolet C radiation…”
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Ocular manifestations of xeroderma pigmentosum: long-term follow-up highlights the role of DNA repair in protection from sun damage by Brooks, Brian P, Thompson, Amy H, Bishop, Rachel J, Clayton, Janine A, Chan, Chi-Chao, Tsilou, Ekaterini T, Zein, Wadih M, Tamura, Deborah, Khan, Sikandar G, Ueda, Takahiro, Boyle, Jennifer, Oh, Kyu-Seon, Imoto, Kyoko, Inui, Hiroki, Moriwaki, Shin-Ichi, Emmert, Steffen, Iliff, Nicholas T, Bradford, Porcia, Digiovanna, John J, Kraemer, Kenneth H

“…Xeroderma pigmentosum (XP) is a rare autosomal recessive disease caused by mutations in DNA repair genes. Clinical manifestations of XP include mild to extreme…”
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Differential expression profile of Th1/Th2-associated chemokines characterizes Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) and drug-induced hypersensitivity syndrome/drug reaction with eosinophilia and systemic symptoms (DIHS/DRESS) as distinct entities by Miyagawa, Fumi, Hasegawa, Ayako, Imoto, Kyoko, Ogawa, Kohei, Kobayashi, Nobuhiko, Ito, Kayoko, Fujita, Hiroyuki, Aihara, Michiko, Watanabe, Hideaki, Sueki, Hirohiko, Tohyama, Mikiko, Asada, Hideo

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VZV skin-test reaction, but not antibody, is an important predictive factor for postherpetic neuralgia by Imoto, Kyoko, Okazaki, Aiko, Onishi, Fumitake, Miyazaki, Yoshiyuki, Okeda, Masayuki, Yano, Shuichiro, Takao, Yukiko, Gomi, Yasuyuki, Ishikawa, Toyokazu, Okuno, Yoshinobu, Mori, Yasuko, Iso, Hiroyasu, Yamanishi, Koichi, Asada, Hideo

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Persistence of repair proteins at unrepaired DNA damage distinguishes diseases with ERCC2 (XPD) mutations: cancer‐prone xeroderma pigmentosum vs. non‐cancer‐prone trichothiodystrophy by Boyle, Jennifer, Ueda, Takahiro, Oh, Kyu‐Seon, Imoto, Kyoko, Tamura, Deborah, Jagdeo, Jared, Khan, Sikandar G., Nadem, Carine, DiGiovanna, John J., Kraemer, Kenneth H.

“…Patients with xeroderma pigmentosum (XP) have a 1,000‐fold increase in ultraviolet (UV)‐induced skin cancers while trichothiodystrophy (TTD) patients, despite…”
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Nucleotide Excision Repair Proteins Rapidly Accumulate but Fail to Persist in Human XPaE (DDB2 Mutant) Cells by Oh, KyuaSeon, Imoto, Kyoko, Emmert, Steffen, Tamura, Deborah, DiGiovanna, John J, Kraemer, Kenneth H

“…The xeroderma pigmentosum (XP-E) DNA damage binding protein (DDB2) is involved in early recognition of global genome DNA damage during DNA nucleotide excision…”
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Nucleotide Excision Repair Proteins Rapidly Accumulate but Fail to Persist in Human XP-E (DDB2 Mutant) Cells by Oh, Kyu-Seon, Imoto, Kyoko, Emmert, Steffen, Tamura, Deborah, DiGiovanna, John J., Kraemer, Kenneth H.

“…The xeroderma pigmentosum (XP‐E) DNA damage binding protein (DDB2) is involved in early recognition of global genome DNA damage during DNA nucleotide excision…”
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