Search Results - "Immunomedicine"

Engineered immunologic niche monitors checkpoint blockade response and probes mechanisms of resistance by Raghani, Ravi M., Urie, Russell R., Ma, Jeffrey A., Escalona, Guillermo, Schrack, Ian A., DiLillo, Katarina M., Kandagatla, Pridvi, Decker, Joseph T., Morris, Aaron H., Arnold, Kelly B., Jeruss, Jacqueline S., Shea, Lonnie D.

“…Antibodies to programmed cell death protein 1 (anti‐PD‐1) have become a promising immunotherapy for triple negative breast cancer (TNBC), blocking PD‐L1…”
Get full text

The use of transcriptomic data in developing biomarkers in breast cancer by Albitar, Maher, Goy, Andre, Pecora, Andrew, Graham, Deena, McNamara, Donna, Charifa, Ahmad, IP, Andrew, Ma, Wanlong, Waintraub, Stanley

“…HER2 and hormone receptors are biomarkers for selecting breast cancer therapy and predicting outcomes. In the era of antibody‐drug conjugates (ADC), a…”
Get full text

Purinergic signaling and purine base metabolism at the crossroads between immunity, metabolism, and cancer: A review by Geitgey, Delaney K., Melendez, Anja J., Caldeira‐Botelho, Raquel, Kemp, Melissa L., Henry, Curtis J.

“…In addition to its universally known role in transferring genetic material, DNA nucleotides and nucleosides are regarded as the most ancient form of…”
Get full text

Programmed death‐ligand 1 expression in Epstein‐Barr virus positive nasopharyngeal cancer by Alfagih, Abdulhameed, Rahman, Muhammad Amin Ur, Al‐Dandan, Sadeq, Alrehaili, Salem, Wani, Tariq, Malki, Abdulrahim Al, Zahrani, Ali Al, Bakhribah, Hatoon

“…Nasopharyngeal cancer (NPC) is common in Saudi Arabia; Most cases are related to the Epstein‐Barr virus (EBV), which is associated with treatment failure and a…”
Get full text

Metabolic inhibitor screening identifies dihydrofolate reductase as an inducer of the tumor immune escape mediator CD24 by Boese, Austin C., Hwang, Jung Seok, Young, Isabelle, Malin, Courteney M., Avalos, Vanessa, Kang, JiHoon, Kang, Sumin

“…Immune checkpoint inhibitors (ICIs) have improved the clinical management of some cancer cases, yet patients still fail to respond to immunotherapy…”
Get full text

Comparing VIP and PD‐L1 expression as cancer biomarkers by Liu, Jojo Y., Zhang, Hanwen, Ravindranathan, Sruthi, Owonikoko, Taofeek K., El‐Rayes, Bassel F., Liu, Yuan, Waller, Edmund K.

“…Immune checkpoint molecules are critical targets of cancer therapies due to their ability to modulate immune responses to cancer. Vasoactive intestinal peptide…”
Get full text

Infections in hematologic malignancy patients treated by CD19 chimeric antigen receptor T‐cell therapy by Zhou, Linghui, Tan Su Yin, Elaine, Zhao, Houli, Ding, Shuyi, Hu, Yongxian, Huang, He

“…Increasing use of chimeric antigen receptor‐T (CAR‐T) cell therapy has significantly improved the survival of hematologic malignancy patients, but CAR‐T cell…”
Get full text

Chimeric antigen receptor‐engineered adoptive cell therapy for AML: Current status and future perspectives by Huang, Yue, Shao, Mi, Wang, Yiyun, Huang, He

“…Acute myeloid leukemia (AML) is one of the lethal hematological malignancies with high relapse rates and poor prognosis. Since chimeric antigen receptor…”
Get full text

The breakthrough and the future: CD20 chimeric antigen receptor T‐cell therapy for hematologic malignancies by Tan Su Yin, Elaine, Hu, Yong Xian, Huang, He

“…Chimeric antigen receptors (CAR) T‐cell therapy is one of the most effective treatments in curing hematologic malignancies. Besides the four CD19 CAR T‐cells…”
Get full text

Special issue: CAR‐T cell therapy for hematological malignancies by Hu, Yongxian, Huang, He

Get full text

HLA‐matched allogeneic anti‐CD19 CAR‐T therapy in treating a relapsed/refractory acute lymphoblastic leukemia patient with high tumor burden by Huang, Yue, Yu, Qin, Yin, Elaine Tan Su, Wei, Guoqing, Wu, Wenjun, Chang, Alex H., Huang, He, Hu, Yongxian

“…The genetically engineered chimeric antigen receptor T cell (CAR‐T) therapy has shown remarkable clinical efficacy in the treatment of hematological…”
Get full text

CAR T cell therapy in advanced B‐ALL with heavy disease burden by Tang, Kaiting, Ling, Zhuojun, Pan, Jing, Huang, He

“…In recent years, CD19‐directed chimeric antigen receptor (CAR) T cell therapy has exhibited significant potency for treating pediatric relapsed or refractory…”
Get full text

The effects of tumor‐derived exosomes on T‐cell function and efficacy of cancer immunotherapy by Hao, Yuanyuan, Chen, Panpan, Zhang, Xuzhao, Shao, Yanping, Xu, Yang, Qian, Wenbin

“…Tumor‐derived exosomes (TEXs) are a class of extracellular vesicles which play an important role in the tumor microenvironment. These vesicles have multiple…”
Get full text

Non‐BCMA targeted CAR‐T cell therapies for multiple myeloma by Wang, Xiangmin, Pan, Bin, Huang, He, Xu, Kailin

“…Despite the emergence of new strategies in recent years, multiple myeloma (MM) is still an incurable disease with poor outcome. As a new treatment, chimeric…”
Get full text

Comprehensive approach for identification of functional FCGR2C alleles resulting in protein expression as a determinant for predicting predisposition to autoimmunity by Lehmann, Dorit, Unterthurner, Sabine, Berg, Verena, Hock, Karin, Ponnuswamy, Padmapriya, Malisauskas, Mantas, Crowe, Brian A., Erguener, Bekir, Bock, Christoph, Hather, Greg, Reipert, Birgit M., Bilic, Ivan

“…The balance of activating and inhibitory signals from the low affinity Fc gamma receptors modulates immune responses triggered by IgG antibody‐immune…”
Get full text

Understanding immunotherapy terminology: An analysis of provider‐patient conversations by Blee, Shannon, Rosenberg, Bari, Switchenko, Jeffrey M., Hianik, Rachel, Thomson, Mary Catherine, Dixon, Margie, Bilen, Mehmet Asim, Pentz, Rebecca D.

“…Background Immunotherapy terminology is complex and can be difficult for patients to understand, threatening informed consent. The aims of this exploratory…”
Get full text

Whole tumor cell vaccines engineered to secrete GM‐CSF (GVAX) by Soiffer, Robert J., Kooshesh, Kameron A., Ho, Vincent

“…Generation of immunity against cancer through vaccination has long been an elusive goal for tumor immunologists. Putative candidates for vaccination targets…”
Get full text

My new normal: A patient's perspective on polymyalgia rheumatica by Paalman, Mark H.

Get full text

Simply Science: The Eighth Annual Bone Marrow Transplant and Cell Therapy Workshop (Orlando, Florida, USA) by Waller, Edmund K.

“…On December 6, 2019, the Eighth Annual Bone Marrow Transplant (BMT) and Cell Therapy Workshop was convened in Orlando, Florida. The workshop was a satellite…”
Get full text

The cross‐disciplinary intellectual stream of ImmunoMedicine by Waller, Edmund K.

Get full text