Search Results - "Immunology letters"

Lymphopenia during the COVID-19 infection: What it shows and what can be learned by Tavakolpour, Soheil, Rakhshandehroo, Taha, Wei, Erin X., Rashidian, Mohammad

Get full text

Nanoparticles and targeted drug delivery in cancer therapy by Bahrami, Behdokht, Hojjat-Farsangi, Mohammad, Mohammadi, Hamed, Anvari, Enayat, Ghalamfarsa, Ghasem, Yousefi, Mehdi, Jadidi-Niaragh, Farhad

“…•Nanomedicine improved the current immunotherapeutic approaches.•Nanomaterials can reduce the adverse effects of current anti-cancer drugs.•Targeted drug…”
Get full text

The impact of ageing on monocytes and macrophages by De Maeyer, Roel P.H., Chambers, Emma S.

“…•Chronic low-grade inflammation – inflammageing- is observed with age.•Macrophages and monocytes are central to the development of inflammageing.•In this…”
Get full text

Ferroptosis mediated DSS-induced ulcerative colitis associated with Nrf2/HO-1 signaling pathway by Chen, Yeru, Zhang, Piao, Chen, Wenru, Chen, Gang

“…•Ferroptosis plays an important role in DSS-induced ulcerative colitis.•Ferroptosis could effectively ameliorate DSS-induced UC by blocking of Nrf2/HO-1…”
Get full text

Inflammatory cytokines IL-17 and TNF-α up-regulate PD-L1 expression in human prostate and colon cancer cells by Wang, Xun, Yang, Lingyun, Huang, Feng, Zhang, Qiuyang, Liu, Sen, Ma, Lin, You, Zongbing

“…Highlights • IL-17 induces PD-L1 protein expression in prostate and colon cancer cells. • TNF-α induces PD-L1 mRNA and protein expression in prostate and colon…”
Get full text

The oral microbiome and the immunobiology of periodontal disease and caries by Costalonga, Massimo, Herzberg, Mark C

“…Highlights • The core oral microbiome and in various ecological niches. • Microbial ecology of the tooth crown and the gingival sulcus. • Sustained high…”
Get full text

Tumor exosomes block dendritic cells maturation to decrease the T cell immune response by Ning, Yongling, Shen, Kai, Wu, Qiyong, Sun, Xiao, Bai, Yu, Xie, Yewen, Pan, Jie, Qi, Chunjian

“…•Tumor exosomes block DC differentiation and induce cell apoptosis.•Tumor exosomes inhibit chemokine receptor expression and DC migration to lymph…”
Get full text

Extracellular nucleotides and nucleosides as signalling molecules by Giuliani, Anna Lisa, Sarti, Alba Clara, Di Virgilio, Francesco

“…•Extracellular nucleotides and nucleosides have a key role in cell-to-cell communication.•Nucleotide release into the extracellular environment can occur by…”
Get full text

CD45 in human physiology and clinical medicine by Rheinländer, Andreas, Schraven, Burkhart, Bommhardt, Ursula

“…•CD45 regulates immune function.•Only few physiological ligands for human CD45 have been identified.•CD45 plays a role in infection, autoimmunity and cancer…”
Get full text

Salmonella infection: Interplay between the bacteria and host immune system by Kurtz, Jonathan R, Goggins, J. Alan, McLachlan, James B.

“…•Salmonella bacteria causes a different array of diseases and infection can be acute or chronic and can be limited to the intestine or distributed…”
Get full text

Mucosal vaccines: Strategies and challenges by Li, Miao, Wang, Yi, Sun, Yuan, Cui, Hongyu, Zhu, Shu J., Qiu, Hua-Ji

“…•This article presents the current knowledge of the strategies and challenges for the development of mucosal vaccines.•Immunization route and vaccine…”
Get full text

Adenosine signaling and the immune system: When a lot could be too much by Antonioli, Luca, Fornai, Matteo, Blandizzi, Corrado, Pacher, Pál, Haskó, György

“…•Inflammation arises from a complex interaction between immune cells and soluble factors aimed at maintaining tissue homeostasis.•Adenosine is a pivotal player…”
Get full text

Targeting the CD73-adenosine axis in immuno-oncology by Allard, David, Chrobak, Pavel, Allard, Bertrand, Messaoudi, Nouredin, Stagg, John

“…•Regulation of CD73 expression in cancer cells.•Regulation of CD73 on host cells.•Prognostic impact of CD73 in cancer.•Overview of CD73 targeting agents in…”
Get full text

CXCR4 signaling in health and disease by Pozzobon, Tommaso, Goldoni, Giacomo, Viola, Antonella, Molon, Barbara

“…Highlights • The CXCR4 ligand: the role of CXCL12. • CXCR4 structure and expression. • CXCR4 homo and hetero-oligomerization. • Physiologic role of CXCR4. •…”
Get full text

CXCL12/CXCR4 signal transduction in diseases and its molecular approaches in targeted-therapy by Mousavi, Ashraf

“…•Chemokines are anti-inflammatory factors in autoimmune diseases.•Chemokines are angiogenic factors, and/or survival/growth factors in cancer cells.•Cancer…”
Get full text

The potential and promise of IL-15 in immuno-oncogenic therapies by Robinson, Tanya O., Schluns, Kimberly S.

“…•Interleukin 15 (IL-15) is immunostimulatory factor targeting CD8 T cells and NK cells that can promote anti-tumor responses and thus can be included among the…”
Get full text

Mesenchymal stromal cells and the innate immune response by Le Blanc, Katarina, Davies, Lindsay C

“…Highlights • MSC interactions with innate immune cells. • MSCs exert both pro- and anti-inflammatory effects. • MSCs are immunomodulatory through cell–cell…”
Get full text

The phagocyte respiratory burst: Historical perspectives and recent advances by Thomas, David C.

“…•The phagocyte respiratory burst is driven by both membrane-bound and cytosolic subunits of the phagocyte NADPH oxidase.•It involves the transfer of electrons…”
Get full text

Toll-like receptors (TLRs) in aquatic animals: Signaling pathways, expressions and immune responses by Rauta, Pradipta R, Samanta, Mrinal, Dash, Hirak R, Nayak, Bismita, Das, Surajit

“…Highlights • Pattern recognition receptors (PRR) in aquatic animals play major role in innate immune response. • TLRs form early barriers against infectious…”
Get full text

Involvement of cystatin C in immunity and apoptosis by Zi, Mengting, Xu, Yuekang

“…•Cystatin C is not only a good index of kidney functions but also involved in immune regulation and apoptosis under pathological conditions.•The involvement of…”
Get full text