Search Results - "Immunobiology (1979)"

The impact of interferon-regulatory factors to macrophage differentiation and polarization into M1 and M2 by Chistiakov, Dimitry A., Myasoedova, Veronika A., Revin, Victor V., Orekhov, Alexander N., Bobryshev, Yuri V.

“…Exposure of monocytes to inflammatory or anti-inflammatory conditions also induces predominant differentiation to proinflammatory (M1) or anti-inflammatory…”
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Reactive oxygen species (ROS) in macrophage activation and function in diabetes by Rendra, Erika, Riabov, Vladimir, Mossel, Dieuwertje M., Sevastyanova, Tatyana, Harmsen, Martin C., Kzhyshkowska, Julia

“…In a diabetic milieu high levels of reactive oxygen species (ROS) are induced. This contributes to the vascular complications of diabetes. Recent studies have…”
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Macrophages: Their role, activation and polarization in pulmonary diseases by Arora, Shweta, Dev, Kapil, Agarwal, Beamon, Das, Pragnya, Syed, Mansoor Ali

“…Macrophages, circulating in the blood or concatenated into different organs and tissues constitute the first barrier against any disease. They are foremost…”
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Macrophages in skin injury and repair by Delavary, Babak Mahdavian, van der Veer, Willem M, van Egmond, Marjolein, Niessen, Frank B, Beelen, Robert H.J

“…Abstract After recruitment to the wound bed, monocytes differentiate into macrophages. Macrophages play a central role in all stages of wound healing and…”
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Macrophages: Supportive cells for tissue repair and regeneration by Chazaud, Bénédicte

“…Abstract Macrophages, and more broadly inflammation, have been considered for a long time as bad markers of tissue homeostasis. However, if it is indisputable…”
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Endothelial injury and thrombotic microangiopathy in COVID-19: Treatment with the lectin-pathway inhibitor narsoplimab by Rambaldi, Alessandro, Gritti, Giuseppe, Micò, Maria Caterina, Frigeni, Marco, Borleri, Gianmaria, Salvi, Anna, Landi, Francesco, Pavoni, Chiara, Sonzogni, Aurelio, Gianatti, Andrea, Binda, Francesca, Fagiuoli, Stefano, Di Marco, Fabiano, Lorini, Luca, Remuzzi, Giuseppe, Whitaker, Steve, Demopulos, Gregory

“…•Narsoplimab down-modulates SARS-CoV-2-induced activation of the lectin pathway and endothelial cell damage.•Narsoplimab can reduce the thrombotic risk of…”
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Host-pathogen interaction in COVID-19: Pathogenesis, potential therapeutics and vaccination strategies by Varghese, Praveen Mathews, Tsolaki, Anthony G., Yasmin, Hadida, Shastri, Abhishek, Ferluga, Janez, Vatish, Manu, Madan, Taruna, Kishore, Uday

“…[Display omitted] The current coronavirus pandemic, COVID-19, is the third outbreak of disease caused by the coronavirus family, after Severe Acute Respiratory…”
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Research progresses of molecular mechanism of pyroptosis and its related diseases by Gong, Weihua, Shi, Ying, Ren, Jingjing

“…Pyroptosis is a newly discovered untypical form of programmed cell death by inflammatory response, which is dependent on the classic pathway of Caspase-1 and…”
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The role of dectin-1 in health and disease by Kalia, Namarta, Singh, Jatinder, Kaur, Manpreet

“…Dendritic cell-associated C-type lectin-1 (Dectin-1), also known as β-glucan receptor is an emerging pattern recognition receptor (PRR) which belongs to the…”
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Quercetin disrupts tyrosine-phosphorylated phosphatidylinositol 3-kinase and myeloid differentiation factor-88 association, and inhibits MAPK/AP-1 and IKK/NF-κB-induced inflammatory mediators production in RAW 264.7 cells by Endale, Mehari, Park, Seung-Chun, Kim, Suk, Kim, Seung-Hyung, Yang, Yanyan, Cho, Jae Youl, Rhee, Man Hee

“…Abstract Quercetin is a major bioflavonoid widely present in fruits and vegetables. It exhibits anti-inflammatory, anti-tumor, antioxidant properties and…”
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The CCR6-CCL20 axis in humoral immunity and T-B cell immunobiology by Lee, Adrian Y.S., Körner, Heinrich

“…Traditionally, chemokine immunobiology has focused on chemotaxis and the positioning of cells at sites of inflammation and within lymphoid organs. More…”
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Tumor associated macrophages and neutrophils in cancer by Galdiero, Maria Rosaria, Bonavita, Eduardo, Barajon, Isabella, Garlanda, Cecilia, Mantovani, Alberto, Jaillon, Sébastien

“…Abstract The tumor microenvironment is a complex framework, in which myeloid cells play important roles in sculpting cancer development from tumor initiation…”
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Role of myeloid cells in the immunosuppressive microenvironment in gliomas by Locarno, Chiara V., Simonelli, Matteo, Carenza, Claudia, Capucetti, Arianna, Stanzani, Elisabetta, Lorenzi, Elena, Persico, Pasquale, Della Bella, Silvia, Passoni, Lorena, Mavilio, Domenico, Bonecchi, Raffaella, Locati, Massimo, Savino, Benedetta

“…Glioma is the most common primary brain cancer, and half of patients present a diagnosis of glioblastoma (GBM), its most aggressive and lethal form…”
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Anti-inflammatory activity of IL-37 in asthmatic children: Correlation with inflammatory cytokines TNF-α, IL-β, IL-6 and IL-17A by Charrad, Rihab, Berraïes, Anissa, Hamdi, Besma, Ammar, Jamel, Hamzaoui, Kamel, Hamzaoui, Agnes

“…Abstract Background The aim of this study was to assess interleukin (IL)-37 production in asthmatic children in serum and induced sputum and to look to the…”
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Human macrophage polarization in vitro : Maturation and activation methods compared by Vogel, Daphne Y.S, Glim, Judith E, Stavenuiter, Andrea W.D, Breur, Marjolein, Heijnen, Priscilla, Amor, Sandra, Dijkstra, Christine D, Beelen, Robert H.J

“…Abstract Macrophages form a heterogeneous cell population displaying multiple functions, and can be polarized into pro- (M1) or anti-inflammatory (M2)…”
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Nanoparticle-induced immune response: Health risk versus treatment opportunity? by Pondman, Kirsten, Le Gac, Séverine, Kishore, Uday

“…Nanoparticles (NPs) are not only employed in many biomedical applications in an engineered form, but also occur in our environment, in a more hazardous form…”
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Lactate and short chain fatty acids produced by microbial fermentation downregulate proinflammatory responses in intestinal epithelial cells and myeloid cells by Iraporda, Carolina, Errea, Agustina, Romanin, David E, Cayet, Delphine, Pereyra, Elba, Pignataro, Omar, Sirard, Jean Claude, Garrote, Graciela L, Abraham, Analía G, Rumbo, Martín

“…Highlights • Lactate & SCFAs regulate proinflammatory activation of epithelial and myeloid cells. • Butyrate/propionate are effective at lower concentrations…”
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Depletion of tumor-associated macrophages enhances the anti-tumor effect of docetaxel in a murine epithelial ovarian cancer by Lu, Xiaofen, Meng, Tengteng

“…Docetaxel (DTXL), a new member of the taxoid family, has been used for cancer treatment. However, increasing cases of DTXL resistance have been reported…”
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The complement system in cancer: Ambivalence between tumour destruction and promotion by Mamidi, Srinivas, Höne, Simon, Kirschfink, Michael

“…Abstract Constituting a part of the innate immune system, the complement system consists of over 50 proteins either acting as part of a 3-branch activation…”
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Toll-like receptor stimulation in cancer: A pro- and anti-tumor double-edged sword by Dajon, Marion, Iribarren, Kristina, Cremer, Isabelle

“…Abstract Toll-like receptors (TLRs) are a family of transmembrane receptors that recognize various pathogen- and damage-associated molecular pattern molecules…”
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