Search Results - "Immonen, Arto"

Detection improvement of gliomas in hyperspectral imaging of protoporphyrin IX fluorescence – in vitro comparison of visual identification and machine thresholds by Lehtonen, Samu J.R., Vrzakova, Hana, Paterno, Jussi J., Puustinen, Sami, Bednarik, Roman, Hauta-Kasari, Markku, Haneishi, Hideaki, Immonen, Arto, Jääskeläinen, Juha E., Kämäräinen, Olli-Pekka, Elomaa, Antti-Pekka

“…•5-aminolevulinic acid (5-ALA) is used in fluorescence guided surgery (FGS) of gliomas.•Glioma cells are detected with 5-ALA-induced protoporphyrin IX (PpIX)…”
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Immunohistochemical Characterization and Sensitivity to Human Adenovirus Serotypes 3, 5, and 11p of New Cell Lines Derived from Human Diffuse Grade II to IV Gliomas by Niittykoski, Minna, von Und Zu Fraunberg, Mikael, Martikainen, Miika, Rauramaa, Tuomas, Immonen, Arto, Koponen, Susanna, Leinonen, Ville, Vähä-Koskela, Markus, Zhang, Qiwei, Kühnel, Florian, Mei, Ya-Fang, Ylä-Herttuala, Seppo, Jääskeläinen, Juha E, Hinkkanen, Ari

“…Oncolytic adenoviruses show promise in targeting gliomas because they do not replicate in normal brain cells. However, clinical responses occur only in a…”
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Thymidine kinase gene therapy for human malignant glioma, using replication-deficient retroviruses or adenoviruses by Sandmair, A M, Loimas, S, Puranen, P, Immonen, A, Kossila, M, Puranen, M, Hurskainen, H, Tyynelä, K, Turunen, M, Vanninen, R, Lehtolainen, P, Paljärvi, L, Johansson, R, Vapalahti, M, Ylä-Herttuala, S

“…Herpes simplex virus thymidine kinase (HSV tk) gene therapy combined with ganciclovir (GCV) medication is a potential new method for the treatment of malignant…”
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Temporal anteroinferior encephalocele by Saavalainen, Taavi, Jutila, Leena, Mervaala, Esa, Kalviainen, Reetta, Vanninen, Ritva, Immonen, Arto

“…Objective: To report the increasing frequency with which temporal anteroinferior encephalocele is a cause of adult temporal lobe epilepsy, to illustrate the…”
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Temporal anteroinferior encephalocele: An underrecognized etiology of temporal lobe epilepsy? by Saavalainen, Taavi, Jutila, Leena, Mervaala, Esa, Kälviäinen, Reetta, Vanninen, Ritva, Immonen, Arto

“…OBJECTIVE:To report the increasing frequency with which temporal anteroinferior encephalocele is a cause of adult temporal lobe epilepsy, to illustrate the…”
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Safety profile of plasmid/liposomes and virus vectors in clinical gene therapy by Wirth, Thomas, Hedman, Marja, Mäkinen, Kimmo, Manninen, Hannu, Immonen, Arto, Vapalahti, Matti, Ylä-Herttuala, Seppo

“…Despite of more than 500 gene therapy trials worldwide very little systematic safety information is available from gene therapy. Safety information was…”
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Increased expression of caspase 2 in experimental and human temporal lobe epilepsy by Narkilahti, Susanna, Jutila, Leena, Alafuzoff, Irina, Karkola, Kari, Paljärvi, Leo, Immonen, Arto, Vapalahti, Matti, Mervaala, Esa, Kälviäinen, Reetta, Pitkänen, Asla

“…Temporal lobe epilepsy (TLE) is often caused by a neurodegenerative brain insult that triggers epileptogenesis, and eventually results in spontaneous seizures,…”
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Epilepsy after aneurysmal subarachnoid hemorrhage: A population-based, long-term follow-up study by Huttunen, Jukka, Kurki, Mitja I, von und zu Fraunberg, Mikael, Koivisto, Timo, Ronkainen, Antti, Rinne, Jaakko, Jääskeläinen, Juha E, Kälviäinen, Reetta, Immonen, Arto

“…OBJECTIVE:The aim was to elucidate the incidence and risk factors of epilepsy after subarachnoid hemorrhage (SAH) from saccular intracranial aneurysm (sIA) in…”
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Long‐term epilepsy surgery outcomes in patients with MRI‐negative temporal lobe epilepsy by Immonen, Arto, Jutila, Leena, Muraja‐Murro, Anu, Mervaala, Esa, Äikiä, Marja, Lamusuo, Salla, Kuikka, Jyrki, Vanninen, Esko, Alafuzoff, Irina, Ikonen, Aki, Vanninen, Ritva, Vapalahti, Matti, Kälviäinen, Reetta

“…Summary Purpose:  The outcome of surgery in patients with temporal lobe epilepsy (TLE) and normal high‐resolution magnetic resonance imaging (MRI) has been…”
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AdvHSV-tk Gene Therapy with Intravenous Ganciclovir Improves Survival in Human Malignant Glioma: A Randomised, Controlled Study by Immonen, Arto, Vapalahti, Matti, Tyynelä, Kristiina, Hurskainen, Heleena, Sandmair, Anu, Vanninen, Ritva, Langford, Gillian, Murray, Neil, Ylä-Herttuala, Seppo

“…Malignant glioma is a devastating brain tumor with no effective treatment. This randomised, controlled study involved 36 patients with operable primary or…”
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Facial nerve function and hearing after microsurgical removal of sporadic vestibular schwannomas in a population-based cohort by Taha, Ismail, Hyvärinen, Antti, Ranta, Antti, Kämäräinen, Olli-Pekka, Huttunen, Jukka, Mervaala, Esa, Löppönen, Heikki, Rauramaa, Tuomas, Ronkainen, Antti, Jääskeläinen, Juha E., Immonen, Arto, Danner, Nils

“…Background Vestibular schwannoma (VS) is a benign tumor originating from the vestibulocochlear nerve. The optimal treatment strategy is debated, since surgery…”
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Epilepsy-associated long-term mortality after aneurysmal subarachnoid hemorrhage by Huttunen, Jukka, Lindgren, Antti, Kurki, Mitja I, Huttunen, Terhi, Frösen, Juhana, Koivisto, Timo, von und zu Fraunberg, Mikael, Immonen, Arto, Jääskeläinen, Juha E, Kälviäinen, Reetta

“…OBJECTIVE:To elucidate the epilepsy-associated causes of death and subsequent excess long-term mortality among 12-month survivors of subarachnoid hemorrhage…”
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Locating and Outlining the Cortical Motor Representation Areas of Facial Muscles With Navigated Transcranial Magnetic Stimulation by Säisänen, Laura, Julkunen, Petro, Kemppainen, Samuli, Danner, Nils, Immonen, Arto, Mervaala, Esa, Määttä, Sara, Muraja-Murro, Anu, Könönen, Mervi

“…Abstract BACKGROUND: Navigated transcranial magnetic stimulation (nTMS) has become established as an accurate noninvasive technique for mapping the functional…”
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Antidepressant Use After Aneurysmal Subarachnoid Hemorrhage: A Population-Based Case–Control Study by Huttunen, Jukka, Lindgren, Antti, Kurki, Mitja I, Huttunen, Terhi, Frösen, Juhana, von und zu Fraunberg, Mikael, Koivisto, Timo, Kälviäinen, Reetta, Räikkönen, Katri, Viinamäki, Heimo, Jääskeläinen, Juha E, Immonen, Arto

“…BACKGROUND AND PURPOSE—To elucidate the predictors of antidepressant use after subarachnoid hemorrhage from saccular intracranial aneurysm (sIA-SAH) in a…”
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MicroRNA-Attenuated Clone of Virulent Semliki Forest Virus Overcomes Antiviral Type I Interferon in Resistant Mouse CT-2A Glioma by Martikainen, Miika, Niittykoski, Minna, von und zu Fraunberg, Mikael, Immonen, Arto, Koponen, Susanna, van Geenen, Maartje, Vähä-Koskela, Markus, Ylösmäki, Erkko, Jääskeläinen, Juha E, Saksela, Kalle, Hinkkanen, Ari

“…Glioblastoma is a terminal disease with no effective treatment currently available. Among the new therapy candidates are oncolytic viruses capable of…”
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Long-term memory performance after surgical treatment of unilateral temporal lobe epilepsy (TLE) by Jutila, Leena, Äikiä, Marja, Immonen, Arto, Mervaala, Esa, Alafuzoff, Irina, Kälviäinen, Reetta

“…Highlights • Long-term memory performance after TLE surgery was evaluated. • Verbal learning and memory declined in both left and right TLE groups. •…”
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Towards Clinical Hyperspectral Imaging (HSI) Standards: Initial Design for a Microneurosurgical HSI Database by Puustinen, Sami, Hyttinen, Joni, Hisuin, Gemal, Vrzakova, Hana, Huotarinen, Antti, Falt, Pauli, Hauta-Kasari, Markku, Immonen, Arto, Koivisto, Timo, Jaaskelainen, Juha E, Elomaa, Antti-Pekka

“…Hyperspectral imaging (HSI) can enhance the recognition of normal and pathological tissues exposed during microscopic or endoscopic surgeries. However, robust…”
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Lentivirus vector‑mediated genetic manipulation of oncogenic pathways induces tumor formation in rabbit brain by Ahmad, Farizan, Hyvärinen, Anna, Pirinen, Agnieszka, Olsson, Venla, Rummukainen, Jaana, Immonen, Arto, Närväinen, Johanna, Tuunanen, Pasi, Liimatainen, Timo, Kärkkäinen, Virve, Koistinaho, Jari, Ylä-Ηerttuala, Seppo

“…Translation of promising experimental therapies from rodent models to clinical success has been complicated as the novel therapies often fail in clinical…”
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Non-invasive preoperative localization of primary motor cortex in epilepsy surgery by navigated transcranial magnetic stimulation by Säisänen, Laura, Könönen, Mervi, Julkunen, Petro, Määttä, Sara, Vanninen, Ritva, Immonen, Arto, Jutila, Leena, Kälviäinen, Reetta, Jääskeläinen, Juha E, Mervaala, Esa

“…Summary Background Navigated transcranial magnetic stimulation (nTMS) is a non-invasive method to localize the primary motor cortex (M1). Objective/Hypothesis…”
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Cystatin C expression is associated with granule cell dispersion in epilepsy by Pirttilä, Terhi J., Manninen, Anni, Jutila, Leena, Nissinen, Jari, Kälviäinen, Reetta, Vapalahti, Matti, Immonen, Arto, Paljärvi, Leo, Karkola, Kari, Alafuzoff, Irina, Mervaala, Esa, Pitkänen, Asla

“…Human temporal lobe epilepsy (TLE) is associated with cellular alterations (eg, hilar cell death, neurogenesis, and granule cell dispersion) in the dentate…”
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