Search Results - "Imler, J.L."

Two distinct pathways can control expression of the gene encoding the Drosophila antimicrobial peptide metchnikowin by Levashina, Elena A, Ohresser, Serge, Lemaitre, Bruno, Imler, Jean-Luc

“…Metchnikowin is a recently discovered proline-rich peptide from Drosophila with antibacterial and antifungal properties. Like most other antimicrobial peptides…”
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Treatment of l(2)mbn Drosophila tumorous blood cells with the steroid hormone ecdysone amplifies the inducibility of antimicrobial peptide gene expression by Dimarcq, Jean-Luc, Imler, Jean-Luc, Lanot, Rene, Alan B. Ezekowitz, R, Hoffmann, Jules A, A. Janeway, Charles, Lagueux, Marie

“…Insects rely on both humoral and cellular mechanisms to defend themselves against microbial infections. The humoral response involves synthesis of a battery of…”
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The c-Ha-ras oncogene and a tumor promoter activate the polyoma virus enhancer by Wasylyk, C, Imler, J L, Perez-Mutul, J, Wasylyk, B

“…A c-Ha-ras oncogene, to a lesser extent the c-Ha-ras proto-oncogene, and the tumor promoter 12-O-tetradecanoylphorbol-13-acetate activate the inactive polyoma…”
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A change in gating mode leading to increased intrinsic Cl‐ channel activity compensates for defective processing in a cystic fibrosis mutant corresponding to a mild form of the disease by Champigny, G., Imler, J.L., Puchelle, E., Dalemans, W., Gribkoff, V., Hinnrasky, J., Dott, K., Barbry, P., Pavirani, A., Lazdunski, M.

“…The effects of the mild cystic fibrosis (CF) mutation P574H were analysed and compared with those of three severe ones (delta I507, delta F508 and R560T)…”
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Identification of three adjacent amino acids of interleukin‐2 receptor beta chain which control the affinity and the specificity of the interaction with interleukin‐2 by Imler, J.L., Miyajima, A., Zurawski, G.

“…The beta chain of the interleukin‐2 (IL‐2) receptor (IL‐2R beta) and the interleukin‐3 (IL‐3) binding protein AIC2A are members of the family of cytokine…”
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Receptor binding and internalization of mouse interleukin-2 derivatives that are partial agonists by IMLER, J.-L, ZURAWSKI, G

“…Mouse interleukin-2 (mIL-2) mutant proteins with subunit-specific receptor binding defects have been previously described. Some of these mutant proteins are…”
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v-jun is a transcriptional activator, but not in all cell-lines by Imler, J L, Ugarte, E, Wasylyk, C, Wasylyk, B

“…The recently isolated v-jun oncogene encodes a protein with sequence homology to the transcription factor AP1, as well as a similar DNA binding specificity. We…”
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Toll-dependent and Toll-independent immune responses in Drosophila by Imler, Jean-Luc, Ferrandon, Dominique, Royet, Julien, Reichhart, Jean-Marc, Hetru, Charles, Hoffmann, Jules A

“…The multifaceted response of the fruitfly Drosophila melanogaster to infection by a wide range of microbes is complex and remarkably efficient. Its most…”
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