Search Results - "Imamoglu, Rahmi"
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Bacterial Hsp70 resolves misfolded states and accelerates productive folding of a multi-domain protein
Published in Nature communications (17-01-2020)“…The ATP-dependent Hsp70 chaperones (DnaK in E. coli ) mediate protein folding in cooperation with J proteins and nucleotide exchange factors ( E. coli DnaJ and…”
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The extracellular chaperone Clusterin enhances Tau aggregate seeding in a cellular model
Published in Nature communications (11-08-2021)“…Spreading of aggregate pathology across brain regions acts as a driver of disease progression in Tau-related neurodegeneration, including Alzheimer’s disease…”
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Calmodulin regulates protease versus co-chaperone activity of a metacaspase
Published in Cell reports (Cambridge) (28-11-2023)“…Metacaspases are ancestral homologs of caspases that can either promote cell death or confer cytoprotection. Furthermore, yeast (Saccharomyces cerevisiae)…”
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Efficient Catalysis of Protein Folding by GroEL/ES of the Obligate Chaperonin Substrate MetF
Published in Journal of molecular biology (27-03-2020)“…The cylindrical chaperonin GroEL and its cofactor GroES mediate ATP-dependent protein folding in Escherichia coli by transiently encapsulating non-native…”
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Hyperthermophilic flavin reductase from Sulfolobus solfataricus P2: Production and biochemical characterization
Published in Biotechnology and applied biochemistry (01-11-2019)“…Nicotinamide adenine dinucleotide phosphate (NAD(P)H)‐flavin oxidoreductases (flavin reductases) catalyze the reduction of flavin by NAD(P)H and provide the…”
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