Search Results - "Imam, Zachary I."
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Kinesin motor density and dynamics in gliding microtubule motility
Published in Scientific reports (10-05-2019)“…Kinesin motors and their associated filaments, microtubules, are essential to many biological processes. The motor and filament system can be reconstituted in…”
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Journal Article -
2
The effects of osmolytes on in vitro kinesin-microtubule motility assays
Published in RSC advances (24-11-2020)“…The gliding motility of microtubule filaments has been used to study the biophysical properties of kinesin motors, as well as being used in a variety of…”
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Journal Article -
3
Steric Pressure among Membrane-Bound Polymers Opposes Lipid Phase Separation
Published in Langmuir (19-04-2016)“…Lipid rafts are thought to be key organizers of membrane–protein complexes in cells. Many proteins that interact with rafts have bulky polymeric components…”
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4
Phase-Separated Liposomes Enhance the Efficiency of Macromolecular Delivery to the Cellular Cytoplasm
Published in Cellular and molecular bioengineering (01-10-2017)“…Introduction From viruses to organelles, fusion of biological membranes is used by diverse biological systems to deliver macromolecules across membrane…”
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Journal Article -
5
Multicomponent and Multiphase Lipid Nanotubes Formed by Gliding Microtubule-Kinesin Motility and Phase-Separated Giant Unilamellar Vesicles
Published in Langmuir (10-12-2019)“…Cytoskeletal filaments and motor proteins are critical components in the transport and reorganization of membrane-based organelles in eukaryotic cells…”
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6
Liposome-Mediated Chemotherapeutic Delivery Is Synergistically Enhanced by Ternary Lipid Compositions and Cationic Lipids
Published in Langmuir (24-09-2019)“…Most small molecule chemotherapeutics must cross one or more cellular membrane barriers to reach their biochemical targets. Owing to the relatively low…”
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Journal Article -
7
Tubulin islands containing slowly hydrolyzable GTP analogs regulate the mechanism and kinetics of microtubule depolymerization
Published in Scientific reports (12-08-2020)“…Dynamic instability of microtubules is characterized by stochastically alternating phases of growth and shrinkage and is hypothesized to be controlled by the…”
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Journal Article -
8
Fabricating Multi-Component Lipid Nanotube Networks using the Gliding Kinesin Motility Assay
Published in Journal of visualized experiments (26-07-2021)“…Lipid nanotube (LNT) networks represent an in vitro model system for studying molecular transport and lipid biophysics with relevance to the ubiquitous lipid…”
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Journal Article -
9
How non-bonding domains affect the active assembly of microtubule spools
Published in Nanoscale (20-06-2019)“…Structural defects can determine and influence various properties of materials, and many technologies rely on the manipulation of defects (e.g., semiconductor…”
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Journal Article -
10
Erratum to: Phase-Separated Liposomes Enhance the Efficiency of Macromolecular Delivery to the Cellular Cytoplasm
Published in Cellular and molecular bioengineering (01-12-2017)Get full text
Journal Article -
11
Kinesin motor density and dynamics in gliding microtubule motility
Published in Scientific reports (10-05-2019)“…Kinesin motors and their associated filaments, microtubules, are essential to many biological processes. The motor and filament system can be reconstituted in…”
Get full text
Journal Article -
12
Steric Pressure among Membrane-Bound Polymers Opposes Lipid Phase Separation
Published in Biophysical journal (16-02-2016)Get full text
Journal Article -
13
GMPCPP-Tubulin Islands Regulate the Mechanism and Kinetics of Microtubule Depolymerization
Published in Biophysical journal (01-02-2020)Get full text
Journal Article Conference Proceeding -
14
The effects of osmolytes on kinesin-microtubule motility assays
Published in RSC advances (24-11-2020)“…The gliding motility of microtubule filaments has been used to study the biophysical properties of kinesin motors, as well as being used in a variety of…”
Get full text
Journal Article