Search Results - "Imakaev, Maxim V."

High-Resolution Mapping of the Spatial Organization of a Bacterial Chromosome by Le, Tung B. K., Imakaev, Maxim V., Mirny, Leonid A., Laub, Michael T.

“…Chromosomes must be highly compacted and organized within cells, but how this is achieved in vivo remains poorly understood. We report the use of chromosome…”
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Compaction and segregation of sister chromatids via active loop extrusion by Goloborodko, Anton, Imakaev, Maxim V, Marko, John F, Mirny, Leonid

“…The mechanism by which chromatids and chromosomes are segregated during mitosis and meiosis is a major puzzle of biology and biophysics. Using polymer…”
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Modeling chromosomes: Beyond pretty pictures by Imakaev, Maxim V., Fudenberg, Geoffrey, Mirny, Leonid A.

“…Recently, Chromosome Conformation Capture (3C) based experiments have highlighted the importance of computational models for the study of chromosome…”
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Activation of the alpha-globin gene expression correlates with dramatic upregulation of nearby non-globin genes and changes in local and large-scale chromatin spatial structure by Ulianov, Sergey V, Galitsyna, Aleksandra A, Flyamer, Ilya M, Golov, Arkadiy K, Khrameeva, Ekaterina E, Imakaev, Maxim V, Abdennur, Nezar A, Gelfand, Mikhail S, Gavrilov, Alexey A, Razin, Sergey V

“…In homeotherms, the alpha-globin gene clusters are located within permanently open genome regions enriched in housekeeping genes. Terminal erythroid…”
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Active chromatin and transcription play a key role in chromosome partitioning into topologically associating domains by Ulianov, Sergey V, Khrameeva, Ekaterina E, Gavrilov, Alexey A, Flyamer, Ilya M, Kos, Pavel, Mikhaleva, Elena A, Penin, Aleksey A, Logacheva, Maria D, Imakaev, Maxim V, Chertovich, Alexander, Gelfand, Mikhail S, Shevelyov, Yuri Y, Razin, Sergey V

“…Recent advances enabled by the Hi-C technique have unraveled many principles of chromosomal folding that were subsequently linked to disease and gene…”
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