Search Results - "Imaimatsu, Kenya"
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Gonadal Sex Differentiation and Ovarian Organogenesis along the Cortical–Medullary Axis in Mammals
Published in International journal of molecular sciences (02-11-2022)“…In most mammals, the sex of the gonads is based on the fate of the supporting cell lineages, which arises from the proliferation of coelomic epithelium (CE)…”
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SOX17-positive rete testis epithelium is required for Sertoli valve formation and normal spermiogenesis in the male mouse
Published in Nature communications (21-12-2022)“…Seminiferous tubules (STs) in the mammalian testes are connected to the rete testis (RT) via a Sertoli valve (SV). Spermatozoa produced in the STs are released…”
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Embryonic cholecystitis and defective gallbladder contraction in the Sox17 -haploinsufficient mouse model of biliary atresia
Published in Development (Cambridge) (15-05-2017)“…The gallbladder excretes cytotoxic bile acids into the duodenum through the cystic duct and common bile duct system. haploinsufficiency causes biliary…”
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CRISPR/Cas9-mediated knock-in of the murine Y chromosomal Sry gene
Published in Journal of Reproduction and Development (2018)“…Mammalian zygote-mediated genome editing via the clustered regularly interspaced short palindromic repeats/CRISPR-associated endonuclease 9 (CRISPR/Cas9)…”
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Molecular and genetic characterization of partial masculinization in embryonic ovaries grafted into male nude mice
Published in PloS one (06-03-2019)“…In most of mammalian embryos, gonadal sex differentiation occurs inside the maternal uterus before birth. In several fetal ovarian grafting experiments using…”
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Partial male-to-female reprogramming of mouse fetal testis by Sertoli cell ablation
Published in Development (Cambridge) (15-07-2023)“…Temporal transcription profiles of fetal testes with Sertoli cell ablation were examined in 4-day culture using a diphtheria toxin (DT)-dependent cell knockout…”
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