Search Results - "Imai, Jun‑Ichi"

The first Japanese biobank of patient‐derived pediatric acute lymphoblastic leukemia xenograft models by Tanaka, Kuniaki, Kato, Itaru, Dobashi, Yuu, Imai, Jun‐ichi, Mikami, Takashi, Kubota, Hirohito, Ueno, Hiroo, Ito, Mamoru, Ogawa, Seishi, Nakahata, Tatsutoshi, Takita, Junko, Toyoda, Hidemi, Ogawa, Chitose, Adachi, Souichi, Watanabe, Shinya, Goto, Hiroaki

“…A lack of practical resources in Japan has limited preclinical discovery and testing of therapies for pediatric relapsed and refractory acute lymphoblastic…”
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Tumor mutation burden and immunological, genomic, and clinicopathological factors as biomarkers for checkpoint inhibitor treatment of patients with non-small-cell lung cancer by Ozaki, Yuki, Muto, Satoshi, Takagi, Hironori, Watanabe, Masayuki, Inoue, Takuya, Fukuhara, Mitsuro, Yamaura, Takumi, Okabe, Naoyuki, Matsumura, Yuki, Hasegawa, Takeo, Ohsugi, Jun, Hoshino, Mika, Shio, Yutaka, Tanaka, Daisuke, Nanamiya, Hideaki, Imai, Jun-ichi, Isogai, Takao, Watanabe, Shinya, Suzuki, Hiroyuki

“…Cancer treatment using immune checkpoint inhibitors is widely used, although biomarkers predictive of response are not well established. However, both the…”
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Constitutive activation of nuclear factor‐κB is preferentially involved in the proliferation of basal‐like subtype breast cancer cell lines by Yamaguchi, Noritaka, Ito, Taku, Azuma, Sakura, Ito, Emi, Honma, Reiko, Yanagisawa, Yuka, Nishikawa, Akira, Kawamura, Mika, Imai, Jun‐ichi, Watanabe, Shinya, Semba, Kentaro, Inoue, Jun‐ichiro

“…Constitutive nuclear factor (NF)‐κB activation is thought to be involved in survival, invasion, and metastasis in various types of cancers. However, neither…”
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Evaluation of anticancer agents using patient-derived tumor organoids characteristically similar to source tissues by Tamura, Hirosumi, Higa, Arisa, Hoshi, Hirotaka, Hiyama, Gen, Takahashi, Nobuhiko, Ryufuku, Masae, Morisawa, Gaku, Yanagisawa, Yuka, Ito, Emi, Imai, Jun-Ichi, Dobashi, Yuu, Katahira, Kiyoaki, Soeda, Shu, Watanabe, Takafumi, Fujimori, Keiya, Watanabe, Shinya, Takagi, Motoki

“…Patient-derived tumor xenograft models represent a promising preclinical cancer model that better replicates disease, compared with traditional cell culture;…”
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Clinical implication of oncogenic somatic mutations in early-stage cervical cancer with radical hysterectomy by Watanabe, Takafumi, Nanamiya, Hideaki, Kojima, Manabu, Nomura, Shinji, Furukawa, Shigenori, Soeda, Shu, Tanaka, Daisuke, Isogai, Takao, Imai, Jun-ichi, Watanabe, Shinya, Fujimori, Keiya

“…It is well known that tumour initiation and progression are primarily an accumulation of genetic mutations. The mutation status of a tumour may predict…”
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Clinical relevance of oncogenic driver mutations identified in endometrial carcinoma by Watanabe, Takafumi, Nanamiya, Hideaki, Kojima, Manabu, Nomura, Shinji, Furukawa, Shigenori, Soeda, Shu, Tanaka, Daisuke, Isogai, Takao, Imai, Jun-ichi, Watanabe, Shinya, Fujimori, Keiya

“…•Comprehensive somatic mutations profiling in endometrial carcinoma.•Relationships between somatic mutations and clinicopathological…”
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NOTCH3 Signaling Pathway Plays Crucial Roles in the Proliferation of ErbB2-Negative Human Breast Cancer Cells by YAMAGUCHI, Noritaka, OYAMA, Tetsunari, KAWAMURA, Mika, IMAI, Jun-Ichi, OHWADA, Susumu, TATSUTA, Kuniaki, INOUE, Jun-Ichiro, SEMBA, Kentaro, WATANABE, Shinya, ITO, Emi, SATOH, Hitoshi, AZUMA, Sakura, HAYASHI, Mitsuhiro, SHIMIZU, Ken, HONMA, Reiko, YANAGISAWA, Yuka, NISHIKAWA, Akira

“…ErbB2-negative breast tumors represent a significant therapeutic hurdle because of a lack of effective molecular targets. Although NOTCH proteins are known to…”
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Identification and clinical significance of somatic oncogenic mutations in epithelial ovarian cancer by Watanabe, Takafumi, Nanamiya, Hideaki, Endo, Yuta, Kojima, Manabu, Nomura, Shinji, Furukawa, Shigenori, Soeda, Shu, Tamura, Hirosumi, Ryufuku, Masae, Tanaka, Daisuke, Isogai, Takao, Imai, Jun-Ichi, Watanabe, Shinya, Fujimori, Keiya

“…Epithelial ovarian cancer (EOC) is a heterogeneous disease with diverse clinicopathological features and behaviors, and its heterogeneity may be concerned with…”
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Differentiation of ovarian serous carcinoma from ovarian clear cell carcinoma using a 10-gene signature selected by comprehensive gene expression analysis by Nomura, Shinji, Watanabe, Takafumi, Honma, Reiko, Matsukura, Susumu, Ito, Emi, Imai, Jun-ichi, Kiko, Yuichiro, Suzuki, Osamu, Hashimoto, Yuko, Kojima, Manabu, Furukawa, Shigenori, Soeda, Shu, Watanabe, Shinya, Fujimori, Keiya

“…Aim:Ovarian serous carcinoma (OSC) and ovarian clear cell carcinoma (OCCC) are two major histological types of epithelial ovarian carcinoma (EOC), each with…”
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Evaluation system for arrhythmogenic potential of drugs using human-induced pluripotent stem cell-derived cardiomyocytes and gene expression analysis by Higa, Arisa, Hoshi, Hirotaka, Yanagisawa, Yuka, Ito, Emi, Morisawa, Gaku, Imai, Jun-ichi, Watanabe, Shinya, Takagi, Motoki

“…In recent years, human-induced pluripotent stem cell-derived cardiomyocytes (hiPS-CMs) have been widely used to develop evaluation systems for drug…”
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Diffusion of Carbon in Niobium and Molybdenum by Imai, Jun-ichi, Taguchi, Osamu, Tiwari, Gyanendra Prasad, Iijima, Yoshiaki

“…Diffusion coefficients of carbon in niobium and molybdenum have been determined by the residual activity method with radioactive tracer 14C in the temperature…”
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Expression screening of 17q12–21 amplicon reveals GRB7 as an ERBB2-dependent oncogene by Saito, Makoto, Kato, Yukiko, Ito, Emi, Fujimoto, Jiro, Ishikawa, Kosuke, Doi, Ayano, Kumazawa, Kentaro, Matsui, Atsuka, Takebe, Shiori, Ishida, Takaomi, Azuma, Sakura, Mochizuki, Hiromi, Kawamura, Yoshifumi, Yanagisawa, Yuka, Honma, Reiko, Imai, Jun-ichi, Ohbayashi, Hirokazu, Goshima, Naoki, Semba, Kentaro, Watanabe, Shinya

“…► We established an integrated analysis system of amplicons. ► Applying this system to 17q12–21 amplicon, we identified GRB7 as an ERBB2-dependent oncogene. ►…”
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TBX19 is overexpressed in colorectal cancer and associated with lymph node metastasis by Ando, Jin, Saito, Motonobu, Imai, Jun-ichi, Ito, Emi, Yanagisawa, Yuka, Honma, Reiko, Saito, Katsuharu, Tachibana, Kazunoshin, Momma, Tomoyuki, Ohki, Shinji, Ohtake, Tohru, Watanabe, Shinya, Waguri, Satoshi, Kono, Koji, Takenoshita, Seiichi

“…The T-box 19 (TBX19) gene encodes a transcription factor characterized by a highly conserved DNA-binding motif (T-box). Recent studies have revealed that TBX19…”
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Influence of inhalation anesthesia assessed by comprehensive gene expression profiling by Sakamoto, Atsuhiro, Imai, Jun-ichi, Nishikawa, Akira, Honma, Reiko, Ito, Emi, Yanagisawa, Yuka, Kawamura, Mika, Ogawa, Ryo, Watanabe, Shinya

“…Although general anesthesia is routinely used as an essential surgical procedure and its harmlessness has been evaluated and endorsed by clinical outcomes,…”
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Alternative splicing of genes during neuronal differentiation of NT2 pluripotential human embryonal carcinoma cells by Wakamatsu, Ai, Imai, Jun-ichi, Watanabe, Shinya, Isogai, Takao

“…We analyzed the mRNA diversity of genes after inducing neuronal differentiation in human NT2 teratocarcinoma cells using all-trans retinoic acid (RA). DNA…”
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Interactive differential evolution using time information required for user's selection: In a case of optimizing fragrance composition by Fukumoto, Makoto, Koga, Shimpei, Inoue, Makoto, Imai, Jun-ichi

“…Interactive Evolutionary Computation (IEC) spreads its area of applications. As an example of the applications, we have already proposed an IEC that optimizes…”
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Application of DNA microarray technology to influenza A/Vietnam/1194/2004 (H5N1) vaccine safety evaluation by Mizukami, Takuo, Imai, Jun-ichi, Hamaguchi, Isao, Kawamura, Mika, Momose, Haruka, Naito, Seishiro, Maeyama, Jun-ichi, Masumi, Atsuko, Kuramitsu, Madoka, Takizawa, Kazuya, Nomura, Nobuo, Watanabe, Shinya, Yamaguchi, Kazunari

“…Summary We propose that DNA microarray analysis can be used in the quality control of pandemic and endemic influenza vaccine. Based on the expression profiles…”
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Facial-component-based bag of words and PHOG descriptor for facial expression recognition by Zisheng Li, Jun-ichi Imai, Kaneko, M.

“…A novel framework of facial appearance and shape information extraction for facial expression recognition is proposed. For appearance extraction, a…”
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Autocrine and Paracrine Interactions between Multiple Myeloma Cells and Bone Marrow Stromal Cells by Growth Arrest-specific Gene 6 Cross-talk with Interleukin-6 by Furukawa, Miki, Ohkawara, Hiroshi, Ogawa, Kazuei, Ikeda, Kazuhiko, Ueda, Koki, Shichishima-Nakamura, Akiko, Ito, Emi, Imai, Jun-ichi, Yanagisawa, Yuka, Honma, Reiko, Watanabe, Shinya, Waguri, Satoshi, Ikezoe, Takayuki, Takeishi, Yasuchika

“…The pathogenesis of multiple myeloma (MM) has not yet been fully elucidated. Our microarray analysis and immunohistochemistry revealed significant…”
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An Extended Interactive Evolutionary Computation Using Heart Rate Variability as Fitness Value for Composing Music Chord Progression by Fukumoto, Makoto, Nakashima, Shuta, Ogawa, Shintaro, Imai, Jun-ichi

“…Interactive Evolutionary Computation (IEC) is known as an efficient method to create media content suited to the individual user. To reduce user’s fatigue,…”
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