Search Results - "Imaculada Frazão Barbosa, Marília"
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Synthesis, characterization and in vitro cytotoxicity of ruthenium(II) metronidazole complexes: Cell cycle arrest at G1/S transition and apoptosis induction in MCF-7 cells
Published in Journal of inorganic biochemistry (01-12-2022)“…Ruthenium compounds are known to be potential drug candidates since they offer the potential for reduced toxicity. Furthermore, the various oxidation states,…”
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The nicotinamide ruthenium(II) complex induces the production of reactive oxygen species (ROS), cell cycle arrest, and apoptosis in melanoma cells
Published in Polyhedron (01-02-2023)“…New complexes with the general formula [RuCl(NIC)(dppb)(X-bipy)]PF6 were prepared by exchanging the Cl-trans ligand to the phosphorus atom by Nicotinamide…”
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Crystal structures and DFT analysis of Palladium(II) complexes with Schiff bases derived from N,N-dialkyl-p-phenylenediamines
Published in Journal of molecular structure (15-03-2020)“…Herein, new palladium(II) complexes with Schiff bases derived from salicylaldehyde and N,N-dialkyl-p-phenylenediamines were obtained. The ligands…”
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Synthesis, crystal structure and leishmanicidal activity of new trimethoprim Ru(III), Cu(II) and Pt(II) metal complexes
Published in Journal of inorganic biochemistry (01-04-2020)“…Leishmaniasis is a parasitic disease caused by protozoa of the genus Leishmania, which has very limited treatment options and affects poor and underdeveloped…”
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Phosphine/diimine ruthenium complexes with Cl−, CO, NO+, NO2−, NO3− and pyridine ligands: Pro-apoptotic activity on triple-negative breast cancer cells and DNA/HSA interactions
Published in Polyhedron (01-04-2018)“…Four phosphine/diimine ruthenium complexes with general formula [RuCl(L)(dppb)(4,4′-Mebipy)](PF6)n (L = CO, NO+, NO2− or pyridine) and one with formula…”
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Pro-apoptotic activity of ruthenium 1-methylimidazole complex on non-small cell lung cancer
Published in Journal of inorganic biochemistry (01-10-2018)“…Herein, novel ruthenium(II) complexes containing 1-methylimidazole as a ligand were obtained with the following formulas: [RuCl(1Meim)(dppb)(bpy)]Cl (1),…”
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Novel ruthenium(II) complexes with cimetidine: DFT calculations and in vitro cytotoxic activities against glioblastoma cell lines
Published in Inorganica Chimica Acta (01-06-2020)“…Four ruthenium cimetidine complexes were synthesized and characterized by usual spectroscopic methods, mass spectrometry and cyclic voltammetry. Density…”
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