Search Results - "Im, Hyeonyeong"
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Development of CIDEA reporter mouse model and its application for screening thermogenic drugs
Published in Scientific reports (16-09-2021)“…Cell death-inducing DNA fragmentation factor-like effector A (CIDEA) is a lipid droplet-associated protein and is a known marker of the thermogenic capacity of…”
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Anti-obesity effects of heat-transformed green tea extract through the activation of adipose tissue thermogenesis
Published in Nutrition & metabolism (03-03-2022)“…Adipose tissue thermogenesis is a potential therapeutic target to increase energy expenditure and thereby combat obesity. The aim of the present study was to…”
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Adipocyte lysoplasmalogenase TMEM86A regulates plasmalogen homeostasis and protein kinase A-dependent energy metabolism
Published in Nature communications (14-07-2022)“…Dysregulation of adipose tissue plasmalogen metabolism is associated with obesity-related metabolic diseases. We report that feeding mice a high-fat diet…”
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Regulatory roles of G-protein coupled receptors in adipose tissue metabolism and their therapeutic potential
Published in Archives of pharmacal research (01-02-2021)“…The high incidence of obesity has increased the need to discover new therapeutic targets to combat obesity and obesity-related metabolic diseases. Obesity is…”
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Anti-obesity effects of the dual-active adenosine A2A/A3 receptor-ligand LJ-4378
Published in International Journal of Obesity (01-12-2022)“…Background and objectives A 2A adenosine receptor (A 2A AR)-mediated signaling in adipose tissues has been investigated as a potential target for…”
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TM4SF5 Knockout Protects Mice From Diet-Induced Obesity Partly by Regulating Autophagy in Adipose Tissue
Published in Diabetes (New York, N.Y.) (01-09-2021)“…Transmembrane 4 L six family member 5 (TM4SF5) functions as a sensor for lysosomal arginine levels and activates the mammalian target of rapamycin complex 1…”
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REEP6 knockout leads to defective β-adrenergic signaling in adipocytes and promotes obesity-related metabolic dysfunction
Published in Metabolism, clinical and experimental (01-05-2022)“…The mobilization and catabolism of lipid energy is a central function of adipocytes that is under the control of the β-adrenergic signaling pathway, and…”
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STK3/STK4 signalling in adipocytes regulates mitophagy and energy expenditure
Published in Nature metabolism (01-03-2021)“…Obesity reduces adipocyte mitochondrial function, and expanding adipocyte oxidative capacity is an emerging strategy to improve systemic metabolism. Here, we…”
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