Search Results - "Ilyas, Sumera"
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Emerging Molecular Therapeutic Targets for Cholangiocarcinoma
Published in Journal of hepatology (01-09-2017)“…Abstract Cholangiocarcinomas (CCAs) are diverse epithelial tumors arising from the liver or large bile ducts with features of cholangiocyte differentiation,…”
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Cholangiocarcinoma — evolving concepts and therapeutic strategies
Published in Nature reviews. Clinical oncology (01-02-2018)“…Key Points Each anatomical subtype of cholangiocarcinoma, intrahepatic (iCCA), perihilar (pCCA) and distal (dCCA), has a distinct epidemiology, biology, and…”
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Liver Cancer Immunity
Published in Hepatology (Baltimore, Md.) (01-01-2021)Get full text
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Cholangiocarcinoma — novel biological insights and therapeutic strategies
Published in Nature reviews. Clinical oncology (01-07-2023)“…In the past 5 years, important advances have been made in the scientific understanding and clinical management of cholangiocarcinoma (CCA). The cellular immune…”
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S2726 A Rare Ca(u)se of Metastatic Renal Cell Carcinoma in the Biliary Tree
Published in The American journal of gastroenterology (01-10-2024)Get full text
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Immunobiology of cholangiocarcinoma
Published in Journal of hepatology (01-09-2023)“…Recent literature has significantly advanced our knowledge and understanding of the tumour immune microenvironment of cholangiocarcinoma. Detailed…”
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EASL-ILCA Clinical Practice Guidelines on the management of intrahepatic cholangiocarcinoma
Published in Journal of hepatology (01-07-2023)“…Intrahepatic cholangiocarcinoma (iCCA) develops inside the liver, between bile ductules and the second-order bile ducts. It is the second most frequent primary…”
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Targeting tumor-associated macrophages and granulocytic myeloid-derived suppressor cells augments PD-1 blockade in cholangiocarcinoma
Published in The Journal of clinical investigation (01-10-2020)“…Immune checkpoint blockade (ICB) has revolutionized cancer therapeutics. Desmoplastic malignancies, such as cholangiocarcinoma (CCA), have an abundant tumor…”
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Targeting cholangiocarcinoma
Published in Biochimica et biophysica acta. Molecular basis of disease (01-04-2018)“…Cholangiocarcinoma (CCA) represents a diverse group of epithelial cancers associated with the biliary tract, and can best be stratified anatomically into…”
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Cholangiocarcinoma
Published in Nature reviews. Disease primers (09-09-2021)“…Cholangiocarcinoma (CCA) is a highly lethal adenocarcinoma of the hepatobiliary system, which can be classified as intrahepatic, perihilar and distal. Each…”
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AASLD practice guidance on primary sclerosing cholangitis and cholangiocarcinoma
Published in Hepatology (Baltimore, Md.) (01-02-2023)Get full text
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Primary Sclerosing Cholangitis as a Premalignant Biliary Tract Disease: Surveillance and Management
Published in Clinical gastroenterology and hepatology (01-11-2015)“…Primary sclerosing cholangitis (PSC) is a premalignant biliary tract disease that confers a significant risk for the development of cholangiocarcinoma (CCA)…”
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Animal models of cholangiocarcinoma
Published in Biochimica et biophysica acta. Molecular basis of disease (01-05-2019)“…Cholangiocarcinoma (CCA) is an aggressive biliary tract malignancy with a poor overall prognosis. There is a critical need to develop effective targeted…”
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Transplant oncology in locally advanced intrahepatic cholangiocarcinoma: One more step on a long road
Published in American journal of transplantation (01-03-2022)“…An analysis by McMillan et al. (page 823) of patients with locally‐advanced unresectable intrahepatic cholangiocarcinoma following liver transplantation shows…”
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Cholangiocarcinoma: molecular pathways and therapeutic opportunities
Published in Seminars in liver disease (01-11-2014)“…Cholangiocarcinoma (CCA) is an aggressive biliary tract malignancy with limited treatment options and low survival rates. Currently, there are no curative…”
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Pathogenesis, Diagnosis, and Management of Cholangiocarcinoma
Published in Gastroenterology (New York, N.Y. 1943) (01-12-2013)“…Cholangiocarcinomas (CCAs) are hepatobiliary cancers with features of cholangiocyte differentiation; they can be classified anatomically as intrahepatic CCA…”
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Hepatology Highlights
Published in Hepatology (Baltimore, Md.) (01-08-2022)Get full text
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IL‐33 facilitates oncogene‐induced cholangiocarcinoma in mice by an interleukin‐6‐sensitive mechanism
Published in Hepatology (Baltimore, Md.) (01-05-2015)“…Cholangiocarcinoma (CCA) is a lethal hepatobiliary neoplasm originating from the biliary apparatus. In humans, CCA risk factors include hepatobiliary…”
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Hepatology highlights
Published in Hepatology (Baltimore, Md.) (01-05-2022)Get full text
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Hepatology highlights
Published in Hepatology (Baltimore, Md.) (01-10-2022)Get full text
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